Genomic-transcriptomic analysis identifies the Syrian hamster as a superior animal model for human diseases - Wang, Chuchu; Cheng, Zhenguo; Miao, Jinxin; Xue, Xia; Dong, Yunshu; Zhao, Li; Guo, Haoran; Wang, Jianyao; Wang, Zhizhong; Lu, Shuangshuang; Fang, Guangming; Peng, Ying; et al. (BMC genomics, 2025)
Keywords: ACE2; Algorithms; Alternative splicing; Angiotensin-converting enzyme 2; Angiotensin-Converting Enzyme 2 - genetics; Animal diseases; Animal Genetics and Genomics; Animal models; Animal models in research; Animals; Biomedical and Life Sciences; Cancer; Cardiovascular disease; Cardiovascular diseases; China; Chromosomes; COVID-19; COVID-19 - genetics; COVID-19 - virology; Cricetinae; Cricetulus - genetics; Disease Models, Animal; Diseases; Gene Expression Profiling; Genes; Genetic aspects; Genetic engineering; Genome; Genomes; Genomic analysis; Genomics; Golden hamster; Heart failure; Homology; Humans; Identification and classification; Infections; Infectious diseases; Laboratory animals; Life Sciences; Medical research; Medicine, Experimental; Mesocricetus - genetics; Methods; Mice; Microarrays; Microbial Genetics and Genomics; Model animal; Omics; Pathogens; Phylogeny; Physiological aspects; Plant Genetics and Genomics; Proteins; Proteomics; Quality control; RNA sequencing; Rodents; SARS-COV-2; SARS-CoV-2 - genetics; Severe acute respiratory syndrome coronavirus 2; Syrian hamster; Transcriptome; Transcriptomes; Transcriptomics; Viral diseases; China; Beijing China; Syrian hamster; Cardiovascular disease; SARS-COV-2; Omics; Model animal; Cancer