Efficient Ex Vivo Engineering and Expansion of Highly Purified Human Hematopoietic Stem and Progenitor Cell Populations for Gene Therapy - Zonari, Erika; Desantis, Giacomo; Petrillo, Carolina; Boccalatte, Francesco E.; Lidonnici, Maria Rosa; Kajaste-Rudnitski, Anna; Aiuti, Alessandro; Ferrari, Giuliana; Naldini, Luigi; Gentner, Bernhard (Stem cell reports, 2017)
Keywords: ADP-ribosyl Cyclase 1 - analysis; Animals; Antigens, CD34 - analysis; Cell Culture Techniques; Cell Engineering - methods; Cell Proliferation; Genetic Therapy - methods; Genetic Vectors - genetics; Hematopoietic Stem Cell Transplantation - methods; Hematopoietic Stem Cells - cytology; Hematopoietic Stem Cells - metabolism; HSC expansion; HSC gene therapy; Humans; lentiviral vector transduction; Lentivirus - genetics; Mice, Inbred NOD; prostaglandin E2; purified HSCs; Transduction, Genetic - methods; UM171; lentiviral vector transduction; UM171; HSC gene therapy; HSC expansion; purified HSCs; prostaglandin E2