Marine Hydroquinone Zonarol Prevents Inflammation and Apoptosis in Dextran Sulfate Sodium-Induced Mice Ulcerative Colitis - Yamada, Sohsuke; Koyama, Tomoyuki; Noguchi, Hirotsugu; Ueda, Yuki; Kitsuyama, Ryo; Shimizu, Hiroya; Tanimoto, Akihide; Wang, Ke-Yong; Nawata, Aya; Nakayama, Toshiyuki; Sasaguri, Yasuyuki; Satoh, Takumi (PloS one, 2014)
Keywords: Administration, Oral; Algae; Animals; Anti-Inflammatory Agents - chemistry; Anti-Inflammatory Agents - pharmacology; Anti-Inflammatory Agents - therapeutic use; Apoptosis; Apoptosis - drug effects; Biology and Life Sciences; Cell activation; Cell Line; Colitis, Ulcerative - chemically induced; Colitis, Ulcerative - drug therapy; Colitis, Ulcerative - pathology; Colon; Colon - pathology; Dextran; Dextran sulfate; Dextran Sulfate - toxicity; Diarrhea; Dictyopteris undulata; Disease Models, Animal; Drinking water; Epithelial cells; Hydroquinone; Hydroquinones - chemistry; Hydroquinones - pharmacology; Hydroquinones - therapeutic use; Immune system; Infiltration; Inflammation - prevention & control; Inflammatory bowel diseases; Interleukin-6 - analysis; Interleukin-6 - genetics; Intestine; Lipopolysaccharides; Lipopolysaccharides - toxicity; Macrophages; Male; Medical treatment; Medicine and Health Sciences; Mesalamine - therapeutic use; Mice; Mice, Inbred ICR; Mucosa; Nitric Oxide Synthase Type II - genetics; Nitric Oxide Synthase Type II - metabolism; Oral administration; Phaeophyceae - chemistry; Phaeophyceae - metabolism; Pharmacology; Polyphenols; Rodents; Sesquiterpenes - chemistry; Sesquiterpenes - isolation & purification; Sesquiterpenes - pharmacology; Sesquiterpenes - therapeutic use; Side effects; Signaling; Sodium; Sulfasalazine; Sulfate; Sulfates; Tumor Necrosis Factor-alpha - analysis; Tumor Necrosis Factor-alpha - genetics; Ulcerative colitis; Japan