The impact of pegylated interferon and ribavirin combination treatment on lipid metabolism and insulin resistance in chronic hepatitis C patients
Lipid profile and insulin resistance (IR) are associated with hepatitis C virus (HCV) and may predict the chronic hepatitis C (CHC) treatment response. The aim of this study was to determine the association between CHC treatment response and lipid profile and IR change during treatment. In total, 20...
Saved in:
| Published in | Clinical and molecular hepatology Vol. 20; no. 1; pp. 38 - 46 |
|---|---|
| Main Authors | , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Korea (South)
Korean Association for the Study of the Liver
01.03.2014
The Korean Association for the Study of the Liver 대한간학회 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 2287-2728 2287-285X 2287-285X |
| DOI | 10.3350/cmh.2014.20.1.38 |
Cover
| Abstract | Lipid profile and insulin resistance (IR) are associated with hepatitis C virus (HCV) and may predict the chronic hepatitis C (CHC) treatment response. The aim of this study was to determine the association between CHC treatment response and lipid profile and IR change during treatment.
In total, 203 CHC patients were reviewed retrospectively between January 2005 and December 2011 at Soon Chun Hyang University Hospital. The lipid profile, homeostasis model for assessment (HOMA) of IR (HOMA-IR), and HOMA of β cells (HOMA-β) were evaluated before interferon plus ribavirin therapy (BTx), at the end of treatment (DTx), and 24 weeks after the end of treatment (ATx).
A sustained virologic response (SVR) was achieved by 81% of all patients (49/60), 60% (n=36) of whom possessed genotype 1, with the remainder being non-genotype-1 (40%, n=24). Apart from age, which was significantly higher in the non-SVR group (SVR, 48.0 ± 11.2 years, mean ± SD; non-SVR, 56.6 ± 9.9 years; P<0.01), there were no significant differences in the baseline characteristics between the SVR and non-SVR groups. In the SVR group, low density lipoprotein-cholesterol (LDL-C) had significantly changed at DTx and ATx compared to BTx. In addition, HOMA-IR and HOMA-β were significantly changed at DTx in the SVR group. Among those with a high baseline insulin resistance (HOMA-IR >2.5), HOMA-IR was significantly changed at DTx in the SVR group.
LDL-C appears to be associated with HCV treatment in SVR patients. Furthermore, eradication of HCV may improve whole-body IR and insulin hypersecretion, as well as high baseline insulin resistance (HOMA-IR >2.5). |
|---|---|
| AbstractList | Background/AimsLipid profile and insulin resistance (IR) are associated with hepatitis C virus (HCV) and may predict the chronic hepatitis C (CHC) treatment response. The aim of this study was to determine the association between CHC treatment response and lipid profile and IR change during treatment.MethodsIn total, 203 CHC patients were reviewed retrospectively between January 2005 and December 2011 at Soon Chun Hyang University Hospital. The lipid profile, homeostasis model for assessment (HOMA) of IR (HOMA-IR), and HOMA of β cells (HOMA-β) were evaluated before interferon plus ribavirin therapy (BTx), at the end of treatment (DTx), and 24 weeks after the end of treatment (ATx).ResultsA sustained virologic response (SVR) was achieved by 81% of all patients (49/60), 60% (n=36) of whom possessed genotype 1, with the remainder being non-genotype-1 (40%, n=24). Apart from age, which was significantly higher in the non-SVR group (SVR, 48.0±11.2 years, mean±SD; non-SVR, 56.6±9.9 years; P<0.01), there were no significant differences in the baseline characteristics between the SVR and non-SVR groups. In the SVR group, low density lipoprotein-cholesterol (LDL-C) had significantly changed at DTx and ATx compared to BTx. In addition, HOMA-IR and HOMA-β were significantly changed at DTx in the SVR group. Among those with a high baseline insulin resistance (HOMA-IR >2.5), HOMA-IR was significantly changed at DTx in the SVR group.ConclusionsLDL-C appears to be associated with HCV treatment in SVR patients. Furthermore, eradication of HCV may improve whole-body IR and insulin hypersecretion, as well as high baseline insulin resistance (HOMA-IR >2.5). Lipid profile and insulin resistance (IR) are associated with hepatitis C virus (HCV) and may predict the chronic hepatitis C (CHC) treatment response. The aim of this study was to determine the association between CHC treatment response and lipid profile and IR change during treatment.BACKGROUND/AIMSLipid profile and insulin resistance (IR) are associated with hepatitis C virus (HCV) and may predict the chronic hepatitis C (CHC) treatment response. The aim of this study was to determine the association between CHC treatment response and lipid profile and IR change during treatment.In total, 203 CHC patients were reviewed retrospectively between January 2005 and December 2011 at Soon Chun Hyang University Hospital. The lipid profile, homeostasis model for assessment (HOMA) of IR (HOMA-IR), and HOMA of β cells (HOMA-β) were evaluated before interferon plus ribavirin therapy (BTx), at the end of treatment (DTx), and 24 weeks after the end of treatment (ATx).METHODSIn total, 203 CHC patients were reviewed retrospectively between January 2005 and December 2011 at Soon Chun Hyang University Hospital. The lipid profile, homeostasis model for assessment (HOMA) of IR (HOMA-IR), and HOMA of β cells (HOMA-β) were evaluated before interferon plus ribavirin therapy (BTx), at the end of treatment (DTx), and 24 weeks after the end of treatment (ATx).A sustained virologic response (SVR) was achieved by 81% of all patients (49/60), 60% (n=36) of whom possessed genotype 1, with the remainder being non-genotype-1 (40%, n=24). Apart from age, which was significantly higher in the non-SVR group (SVR, 48.0 ± 11.2 years, mean ± SD; non-SVR, 56.6 ± 9.9 years; P<0.01), there were no significant differences in the baseline characteristics between the SVR and non-SVR groups. In the SVR group, low density lipoprotein-cholesterol (LDL-C) had significantly changed at DTx and ATx compared to BTx. In addition, HOMA-IR and HOMA-β were significantly changed at DTx in the SVR group. Among those with a high baseline insulin resistance (HOMA-IR >2.5), HOMA-IR was significantly changed at DTx in the SVR group.RESULTSA sustained virologic response (SVR) was achieved by 81% of all patients (49/60), 60% (n=36) of whom possessed genotype 1, with the remainder being non-genotype-1 (40%, n=24). Apart from age, which was significantly higher in the non-SVR group (SVR, 48.0 ± 11.2 years, mean ± SD; non-SVR, 56.6 ± 9.9 years; P<0.01), there were no significant differences in the baseline characteristics between the SVR and non-SVR groups. In the SVR group, low density lipoprotein-cholesterol (LDL-C) had significantly changed at DTx and ATx compared to BTx. In addition, HOMA-IR and HOMA-β were significantly changed at DTx in the SVR group. Among those with a high baseline insulin resistance (HOMA-IR >2.5), HOMA-IR was significantly changed at DTx in the SVR group.LDL-C appears to be associated with HCV treatment in SVR patients. Furthermore, eradication of HCV may improve whole-body IR and insulin hypersecretion, as well as high baseline insulin resistance (HOMA-IR >2.5).CONCLUSIONSLDL-C appears to be associated with HCV treatment in SVR patients. Furthermore, eradication of HCV may improve whole-body IR and insulin hypersecretion, as well as high baseline insulin resistance (HOMA-IR >2.5). Lipid profile and insulin resistance (IR) are associated with hepatitis C virus (HCV) and may predict the chronic hepatitis C (CHC) treatment response. The aim of this study was to determine the association between CHC treatment response and lipid profile and IR change during treatment. In total, 203 CHC patients were reviewed retrospectively between January 2005 and December 2011 at Soon Chun Hyang University Hospital. The lipid profile, homeostasis model for assessment (HOMA) of IR (HOMA-IR), and HOMA of β cells (HOMA-β) were evaluated before interferon plus ribavirin therapy (BTx), at the end of treatment (DTx), and 24 weeks after the end of treatment (ATx). A sustained virologic response (SVR) was achieved by 81% of all patients (49/60), 60% (n=36) of whom possessed genotype 1, with the remainder being non-genotype-1 (40%, n=24). Apart from age, which was significantly higher in the non-SVR group (SVR, 48.0 ± 11.2 years, mean ± SD; non-SVR, 56.6 ± 9.9 years; P<0.01), there were no significant differences in the baseline characteristics between the SVR and non-SVR groups. In the SVR group, low density lipoprotein-cholesterol (LDL-C) had significantly changed at DTx and ATx compared to BTx. In addition, HOMA-IR and HOMA-β were significantly changed at DTx in the SVR group. Among those with a high baseline insulin resistance (HOMA-IR >2.5), HOMA-IR was significantly changed at DTx in the SVR group. LDL-C appears to be associated with HCV treatment in SVR patients. Furthermore, eradication of HCV may improve whole-body IR and insulin hypersecretion, as well as high baseline insulin resistance (HOMA-IR >2.5). Background/Aims: Lipid profile and insulin resistance (IR) are associated with hepatitis C virus (HCV) and may predictthe chronic hepatitis C (CHC) treatment response. The aim of this study was to determine the association betweenCHC treatment response and lipid profile and IR change during treatment. Methods: In total, 203 CHC patients were reviewed retrospectively between January 2005 and December 2011 atSoon Chun Hyang University Hospital. The lipid profile, homeostasis model for assessment (HOMA) of IR (HOMA-IR),and HOMA of β cells (HOMA-β) were evaluated before interferon plus ribavirin therapy (BTx), at the end of treatment(DTx), and 24 weeks after the end of treatment (ATx). Results: A sustained virologic response (SVR) was achieved by 81% of all patients (49/60), 60% (n=36) of whompossessed genotype 1, with the remainder being non-genotype-1 (40%, n=24). Apart from age, which wassignificantly higher in the non-SVR group (SVR, 48.0±11.2 years, mean±SD; non-SVR, 56.6±9.9 years; P<0.01), therewere no significant differences in the baseline characteristics between the SVR and non-SVR groups. In the SVR group,low density lipoprotein-cholesterol (LDL-C) had significantly changed at DTx and ATx compared to BTx. In addition,HOMA-IR and HOMA-β were significantly changed at DTx in the SVR group. Among those with a high baseline insulinresistance (HOMA-IR >2.5), HOMA-IR was significantly changed at DTx in the SVR group. Conclusions: LDL-C appears to be associated with HCV treatment in SVR patients. Furthermore, eradication of HCVmay improve whole-body IR and insulin hypersecretion, as well as high baseline insulin resistance (HOMA-IR >2.5). KCI Citation Count: 1 |
| Author | Kim, Sang Gyune Jeong, Soung Won Kim, Hong Soo Lee, Sae Hwan Kim, Young Seok Jang, Jae Young Jung, Hee Jae Lee, Yun Nah Kim, Boo Sung |
| AuthorAffiliation | 1 Digestive Disease Center and Research Institute, Department of Internal Medicine, Soonchunhyang University Hospital Bucheon, Soonchunhyang University College of Medicine, Bucheon, Korea 2 Institute for Digestive Research, Department of Internal Medicine, Soonchunhyang University Hospital Seoul, Soonchunhyang University College of Medicine, Seoul, Korea 3 Department of Internal Medicine, Soonchunhyang University Hospital Cheonan, Soonchunhyang University College of Medicine, Cheonan, Korea |
| AuthorAffiliation_xml | – name: 1 Digestive Disease Center and Research Institute, Department of Internal Medicine, Soonchunhyang University Hospital Bucheon, Soonchunhyang University College of Medicine, Bucheon, Korea – name: 3 Department of Internal Medicine, Soonchunhyang University Hospital Cheonan, Soonchunhyang University College of Medicine, Cheonan, Korea – name: 2 Institute for Digestive Research, Department of Internal Medicine, Soonchunhyang University Hospital Seoul, Soonchunhyang University College of Medicine, Seoul, Korea |
| Author_xml | – sequence: 1 givenname: Hee Jae surname: Jung fullname: Jung, Hee Jae organization: Digestive Disease Center and Research Institute, Department of Internal Medicine, Soonchunhyang University Hospital Bucheon, Soonchunhyang University College of Medicine, Bucheon, Korea – sequence: 2 givenname: Young Seok surname: Kim fullname: Kim, Young Seok organization: Digestive Disease Center and Research Institute, Department of Internal Medicine, Soonchunhyang University Hospital Bucheon, Soonchunhyang University College of Medicine, Bucheon, Korea – sequence: 3 givenname: Sang Gyune surname: Kim fullname: Kim, Sang Gyune organization: Digestive Disease Center and Research Institute, Department of Internal Medicine, Soonchunhyang University Hospital Bucheon, Soonchunhyang University College of Medicine, Bucheon, Korea – sequence: 4 givenname: Yun Nah surname: Lee fullname: Lee, Yun Nah organization: Digestive Disease Center and Research Institute, Department of Internal Medicine, Soonchunhyang University Hospital Bucheon, Soonchunhyang University College of Medicine, Bucheon, Korea – sequence: 5 givenname: Soung Won surname: Jeong fullname: Jeong, Soung Won organization: Institute for Digestive Research, Department of Internal Medicine, Soonchunhyang University Hospital Seoul, Soonchunhyang University College of Medicine, Seoul, Korea – sequence: 6 givenname: Jae Young surname: Jang fullname: Jang, Jae Young organization: Institute for Digestive Research, Department of Internal Medicine, Soonchunhyang University Hospital Seoul, Soonchunhyang University College of Medicine, Seoul, Korea – sequence: 7 givenname: Sae Hwan surname: Lee fullname: Lee, Sae Hwan organization: Department of Internal Medicine, Soonchunhyang University Hospital Cheonan, Soonchunhyang University College of Medicine, Cheonan, Korea – sequence: 8 givenname: Hong Soo surname: Kim fullname: Kim, Hong Soo organization: Department of Internal Medicine, Soonchunhyang University Hospital Cheonan, Soonchunhyang University College of Medicine, Cheonan, Korea – sequence: 9 givenname: Boo Sung surname: Kim fullname: Kim, Boo Sung organization: Digestive Disease Center and Research Institute, Department of Internal Medicine, Soonchunhyang University Hospital Bucheon, Soonchunhyang University College of Medicine, Bucheon, Korea |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/24757657$$D View this record in MEDLINE/PubMed https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART001859130$$DAccess content in National Research Foundation of Korea (NRF) |
| BookMark | eNqNUk1vEzEQXaEiWkrvnJAlLlwS1uu113tBqiI-IlVCQkXiZnm9s4lTr73YTlF-Bv-YSUILrYSED_587808zzwvTnzwUBQvaTlnjJdvzbieVyWtcZrTOZNPirOqks2skvzbyd2-qeRpcZHSpsTRlBVv2bPitKob3gjenBU_r9dA7Dhpk0kYyASrndMZemJ9hjhADJ5o35NoO31ro_XEhLGzXmeLLzmCziN45Hri7GR7MkLWXXA2jQee9WnrkBUh2ZS1NxgNNdaoaw1Zw4RC2SayIPsdKqUXxdNBuwQXv9fz4uuH99eLT7Orzx-Xi8urmeGyzbMOBONQUlN3eK65bhqgHR8Y5aI1bVmxBh0LYENDmai1FFBK0QrBgXMtOTsv3hx1fRzUjbEqaHtYV0HdRHX55Xqp6hZlJEKXR2gf9EZN0Y467g74w0WIK6VjtsaBkq2uzTBgxKGvtaj0IGpoa1mblkIvBGrRo9bWT3r3Qzt3L0hLtS-swsKqfWFxUlSxffx3R8607UboDX5T1O5BIg9fvF2jjVvFWjRQyT9epxi-byFlNdpkwDntIWyTopxKSXkr9tDXj6CbsI0eK6EYrThvGsFqRL36O6P7VO4aCwHlEWBiSCnC8D8uxSOKsfnQZ-jJun8TfwEOPvTV |
| CitedBy_id | crossref_primary_10_1097_MEG_0000000000001903 crossref_primary_10_1016_j_clinbiochem_2018_07_007 crossref_primary_10_3748_wjg_v23_i9_1697 crossref_primary_10_5144_0256_4947_2015_293 crossref_primary_10_1016_j_aidm_2014_12_003 crossref_primary_10_1186_s12879_015_1268_2 crossref_primary_10_12688_f1000research_109397_1 crossref_primary_10_1007_s12664_019_00935_w crossref_primary_10_1515_prilozi_2017_0003 crossref_primary_10_1111_hepr_12938 crossref_primary_10_1002_aid2_13211 crossref_primary_10_1080_14787210_2019_1653184 crossref_primary_10_1093_cid_ciw362 crossref_primary_10_5009_gnl17179 crossref_primary_10_3390_cells8030252 crossref_primary_10_1016_j_clinre_2016_09_008 crossref_primary_10_1371_journal_pone_0208858 crossref_primary_10_3748_wjg_v22_i46_10226 crossref_primary_10_4254_wjh_v7_i10_1337 crossref_primary_10_3892_etm_2019_7995 crossref_primary_10_1093_ofid_ofz318 crossref_primary_10_1002_lt_25060 crossref_primary_10_1097_MEG_0000000000001215 crossref_primary_10_3390_biomedicines9101491 crossref_primary_10_1186_s12944_015_0119_x crossref_primary_10_18632_oncotarget_25092 crossref_primary_10_1016_j_dld_2015_09_015 crossref_primary_10_1371_journal_pone_0209615 crossref_primary_10_1002_aid2_12054 crossref_primary_10_1586_17474086_2016_1136209 crossref_primary_10_1080_07315724_2015_1072756 |
| Cites_doi | 10.1002/hep.510290632 10.1016/j.jhep.2009.07.008 10.1016/j.jhep.2008.08.006 10.1038/ajg.2010.110 10.1002/hep.21261 10.1111/j.1572-0241.2001.04055.x 10.1128/JVI.68.8.5045-5055.1994 10.1016/j.jhep.2007.07.026 10.1016/0021-9150(87)90287-5 10.1016/j.jhep.2008.12.017 10.1016/S0168-8278(12)60007-5 10.1111/j.1572-0241.2006.01038.x 10.3350/kjhep.2012.18.1.41 10.1007/s005350300063 10.7326/0003-4819-132-9-200005020-00023 10.3748/wjg.v12.i44.7075 10.3350/kjhep.2012.18.1.22 10.5009/gnl.2009.3.2.108 10.1016/S0166-3542(01)00181-4 10.1002/hep.510250632 10.1053/j.gastro.2004.12.049 10.1136/gut.2009.185074 10.1016/S0929-6646(11)60054-5 10.1111/j.1478-3231.2010.02343.x 10.1016/j.cgh.2010.01.022 10.1111/j.1572-0241.2007.01181.x 10.1111/j.1478-3231.2011.02545.x 10.2337/diab.41.2.S97 10.1002/hep.23206 10.1111/j.1872-034X.2008.00439.x |
| ContentType | Journal Article |
| Copyright | 2014. This work is published under http://creativecommons.org/licenses/by-nc/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. Copyright © 2014 by The Korean Association for the Study of the Liver 2014 |
| Copyright_xml | – notice: 2014. This work is published under http://creativecommons.org/licenses/by-nc/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. – notice: Copyright © 2014 by The Korean Association for the Study of the Liver 2014 |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 3V. 7X7 7XB 8FI 8FJ 8FK ABUWG AFKRA AZQEC BENPR CCPQU DWQXO FYUFA GHDGH K9. M0S PHGZM PHGZT PIMPY PJZUB PKEHL PPXIY PQEST PQQKQ PQUKI PRINS 7X8 5PM ADTOC UNPAY DOA ACYCR |
| DOI | 10.3350/cmh.2014.20.1.38 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Health & Medical Collection ProQuest Central (purchase pre-March 2016) Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials ProQuest Central (subscription) ProQuest One ProQuest Central Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Health & Medical Complete (Alumni) Health & Medical Collection (Alumni Edition) ProQuest Central Premium ProQuest One Academic Publicly Available Content Database ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China MEDLINE - Academic PubMed Central (Full Participant titles) Unpaywall for CDI: Periodical Content Unpaywall DOAJ Directory of Open Access Journals Korean Citation Index |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Publicly Available Content Database ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest One Academic Eastern Edition ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest One Health & Nursing ProQuest Central China ProQuest Hospital Collection (Alumni) ProQuest Central ProQuest Health & Medical Complete ProQuest Health & Medical Research Collection Health Research Premium Collection ProQuest One Academic UKI Edition Health and Medicine Complete (Alumni Edition) ProQuest Central Korea ProQuest Central (New) ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE Publicly Available Content Database |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 4 dbid: UNPAY name: Unpaywall url: https://proxy.k.utb.cz/login?url=https://unpaywall.org/ sourceTypes: Open Access Repository – sequence: 5 dbid: BENPR name: ProQuest Central url: http://www.proquest.com/pqcentral?accountid=15518 sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 2287-285X |
| EndPage | 46 |
| ExternalDocumentID | oai_kci_go_kr_ARTI_492378 oai_doaj_org_article_89a4cff364fd4a62af64e9484c91ed66 10.3350/cmh.2014.20.1.38 PMC3992328 24757657 10_3350_cmh_2014_20_1_38 |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GrantInformation_xml | – fundername: the Soonchunhyang University Research Fund |
| GroupedDBID | 5-W 7X7 8FI 8FJ 8JR 8XY 9ZL AAYXX ABUWG ACYCR ADBBV ADRAZ AFKRA ALMA_UNASSIGNED_HOLDINGS AOIJS BAWUL BCNDV BENPR CCPQU CITATION DIK EBD EF. EMOBN FYUFA GROUPED_DOAJ HMCUK HYE IPNFZ KQ8 M48 PGMZT PHGZM PHGZT PIMPY PUEGO RIG RNS RPM SV3 UKHRP CGR CUY CVF ECM EIF NPM 3V. 7XB 8FK AZQEC DWQXO K9. PJZUB PKEHL PPXIY PQEST PQQKQ PQUKI PRINS 7X8 5PM ADTOC AFFHD UNPAY |
| ID | FETCH-LOGICAL-c589t-be635e01c4b58945a77e1b5f31569c902370006e3f71364a86e0869665e55a853 |
| IEDL.DBID | M48 |
| ISSN | 2287-2728 2287-285X |
| IngestDate | Sun Mar 09 07:55:52 EDT 2025 Tue Oct 14 19:08:22 EDT 2025 Wed Oct 29 12:16:42 EDT 2025 Tue Sep 30 16:27:03 EDT 2025 Fri Sep 05 08:12:24 EDT 2025 Tue Oct 07 07:21:11 EDT 2025 Thu Apr 03 07:07:41 EDT 2025 Wed Oct 01 05:05:51 EDT 2025 Thu Apr 24 23:07:45 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 1 |
| Keywords | Insulin resistance Chronic hepatitis C Lipid metabolism |
| Language | English |
| License | http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. cc-by-nc |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c589t-be635e01c4b58945a77e1b5f31569c902370006e3f71364a86e0869665e55a853 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 http://www.e-cmh.org/ G704-001530.2014.20.1.002 |
| OpenAccessLink | https://proxy.k.utb.cz/login?url=https://www.e-cmh.org/upload/pdf/cmh-20-38.pdf |
| PMID | 24757657 |
| PQID | 3125577634 |
| PQPubID | 7084873 |
| PageCount | 9 |
| ParticipantIDs | nrf_kci_oai_kci_go_kr_ARTI_492378 doaj_primary_oai_doaj_org_article_89a4cff364fd4a62af64e9484c91ed66 unpaywall_primary_10_3350_cmh_2014_20_1_38 pubmedcentral_primary_oai_pubmedcentral_nih_gov_3992328 proquest_miscellaneous_1518815968 proquest_journals_3125577634 pubmed_primary_24757657 crossref_primary_10_3350_cmh_2014_20_1_38 crossref_citationtrail_10_3350_cmh_2014_20_1_38 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2014-03-01 |
| PublicationDateYYYYMMDD | 2014-03-01 |
| PublicationDate_xml | – month: 03 year: 2014 text: 2014-03-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | Korea (South) |
| PublicationPlace_xml | – name: Korea (South) – name: Seoul |
| PublicationTitle | Clinical and molecular hepatology |
| PublicationTitleAlternate | Clin Mol Hepatol |
| PublicationYear | 2014 |
| Publisher | Korean Association for the Study of the Liver The Korean Association for the Study of the Liver 대한간학회 |
| Publisher_xml | – name: Korean Association for the Study of the Liver – name: The Korean Association for the Study of the Liver – name: 대한간학회 |
| References | Minuk (10.3350/cmh.2014.20.1.38_ref6) 2000; 132 Rosenzweig (10.3350/cmh.2014.20.1.38_ref17) 1987; 67 Kim (10.3350/cmh.2014.20.1.38_ref33) 2009; 3 Jun (10.3350/cmh.2014.20.1.38_ref1) 2012; 18 Naeem (10.3350/cmh.2014.20.1.38_ref10) 2001; 96 Grasso (10.3350/cmh.2014.20.1.38_ref25) 2009; 51 Dai (10.3350/cmh.2014.20.1.38_ref13) 2009; 50 Bugianesi (10.3350/cmh.2014.20.1.38_ref20) 2012; 56 Poustchi (10.3350/cmh.2014.20.1.38_ref27) 2008; 48 Huang (10.3350/cmh.2014.20.1.38_ref3) 2007; 102 Bugianesi (10.3350/cmh.2014.20.1.38_ref14) 2012; 56 Kim (10.3350/cmh.2014.20.1.38_ref4) 2012; 18 Kawaguchi (10.3350/cmh.2014.20.1.38_ref31) 2007; 102 Quadri (10.3350/cmh.2014.20.1.38_ref12) 2001; 52 Tada (10.3350/cmh.2014.20.1.38_ref15) 2009; 39 Bartenschlager (10.3350/cmh.2014.20.1.38_ref23) 1994; 68 Kuo (10.3350/cmh.2014.20.1.38_ref16) 2011; 110 Shinohara (10.3350/cmh.2014.20.1.38_ref18) 1997; 25 Huang (10.3350/cmh.2014.20.1.38_ref2) 2011; 31 Fattovich (10.3350/cmh.2014.20.1.38_ref29) 2011; 31 Svegliati-Baroni (10.3350/cmh.2014.20.1.38_ref21) 1999; 29 Romero-Gomez (10.3350/cmh.2014.20.1.38_ref30) 2009; 50 Feingold (10.3350/cmh.2014.20.1.38_ref11) 1992; 41 Khattab (10.3350/cmh.2014.20.1.38_ref24) 2010; 105 Delgado-Borrego (10.3350/cmh.2014.20.1.38_ref32) 2010; 8 Moucari (10.3350/cmh.2014.20.1.38_ref26) 2009; 58 Gopal (10.3350/cmh.2014.20.1.38_ref5) 2006; 44 Dai (10.3350/cmh.2014.20.1.38_ref19) 2009; 50 Romero-Gómez (10.3350/cmh.2014.20.1.38_ref22) 2006; 12 Arao (10.3350/cmh.2014.20.1.38_ref7) 2003; 38 Romero-Gómez (10.3350/cmh.2014.20.1.38_ref28) 2005; 128 Saxena (10.3350/cmh.2014.20.1.38_ref9) 2003; 133 White (10.3350/cmh.2014.20.1.38_ref8) 2008; 49 20840397 - Liver Int. 2011 Jan;31(1):66-74 19695729 - J Hepatol. 2009 Dec;51(6):984-90 20431732 - Gut Liver. 2009 Jun;3(2):108-15 12743775 - J Gastroenterol. 2003;38(4):355-60 19845037 - Hepatology. 2009 Dec;50(6):1702-8 11672826 - Antiviral Res. 2001 Nov;52(2):161-71 19231011 - J Hepatol. 2009 Apr;50(4):712-8 11513192 - Am J Gastroenterol. 2001 Aug;96(8):2468-72 15765399 - Gastroenterology. 2005 Mar;128(3):636-41 10787379 - Ann Intern Med. 2000 May 2;132(9):761-2 10347117 - Hepatology. 1999 Jun;29(6):1743-51 21745292 - Liver Int. 2011 Sep;31(8):1155-62 21741004 - J Formos Med Assoc. 2011 Jun;110(6):363-71 16871569 - Hepatology. 2006 Aug;44(2):335-40 14745667 - Swiss Med Wkly. 2003 Dec 13;133(45-46):611-8 19671541 - Gut. 2009 Dec;58(12):1662-9 20156586 - Clin Gastroenterol Hepatol. 2010 May;8(5):458-62 22300466 - J Hepatol. 2012;56 Suppl 1:S56-65 1526345 - Diabetes. 1992 Oct;41 Suppl 2:97-101 17131467 - World J Gastroenterol. 2006 Nov 28;12(44):7075-80 22511899 - Korean J Hepatol. 2012 Mar;18(1):22-8 20234345 - Am J Gastroenterol. 2010 Sep;105(9):1970-7 17977612 - J Hepatol. 2008 Jan;48(1):28-34 8035505 - J Virol. 1994 Aug;68(8):5045-55 18814931 - J Hepatol. 2008 Nov;49(5):831-44 3079540 - Atherosclerosis. 1987 Oct;67(2-3):261-7 22511902 - Korean J Hepatol. 2012 Mar;18(1):41-7 9185775 - Hepatology. 1997 Jun;25(6):1502-6 17222321 - Am J Gastroenterol. 2007 Mar;102(3):570-6 19054155 - Hepatol Res. 2009 Feb;39(2):195-9 17531012 - Am J Gastroenterol. 2007 Jun;102(6):1237-43 |
| References_xml | – volume: 29 start-page: 1743 year: 1999 ident: 10.3350/cmh.2014.20.1.38_ref21 publication-title: Hepatology doi: 10.1002/hep.510290632 – volume: 51 start-page: 984 year: 2009 ident: 10.3350/cmh.2014.20.1.38_ref25 publication-title: J Hepatol doi: 10.1016/j.jhep.2009.07.008 – volume: 49 start-page: 831 year: 2008 ident: 10.3350/cmh.2014.20.1.38_ref8 publication-title: J Hepatol doi: 10.1016/j.jhep.2008.08.006 – volume: 105 start-page: 1970 year: 2010 ident: 10.3350/cmh.2014.20.1.38_ref24 publication-title: Am J Gastroenterol doi: 10.1038/ajg.2010.110 – volume: 44 start-page: 335 year: 2006 ident: 10.3350/cmh.2014.20.1.38_ref5 publication-title: Hepatology doi: 10.1002/hep.21261 – volume: 96 start-page: 2468 year: 2001 ident: 10.3350/cmh.2014.20.1.38_ref10 publication-title: Am J Gastroenterol doi: 10.1111/j.1572-0241.2001.04055.x – volume: 68 start-page: 5045 year: 1994 ident: 10.3350/cmh.2014.20.1.38_ref23 publication-title: J Virol doi: 10.1128/JVI.68.8.5045-5055.1994 – volume: 48 start-page: 28 year: 2008 ident: 10.3350/cmh.2014.20.1.38_ref27 publication-title: J Hepatol doi: 10.1016/j.jhep.2007.07.026 – volume: 67 start-page: 261 year: 1987 ident: 10.3350/cmh.2014.20.1.38_ref17 publication-title: Atherosclerosis doi: 10.1016/0021-9150(87)90287-5 – volume: 50 start-page: 712 year: 2009 ident: 10.3350/cmh.2014.20.1.38_ref19 publication-title: J Hepatol doi: 10.1016/j.jhep.2008.12.017 – volume: 50 start-page: 712 year: 2009 ident: 10.3350/cmh.2014.20.1.38_ref13 publication-title: J Hepatol doi: 10.1016/j.jhep.2008.12.017 – volume: 56 start-page: S56 issue: Suppl 1 year: 2012 ident: 10.3350/cmh.2014.20.1.38_ref14 publication-title: J Hepatol doi: 10.1016/S0168-8278(12)60007-5 – volume: 56 start-page: S56 issue: Suppl 1 year: 2012 ident: 10.3350/cmh.2014.20.1.38_ref20 publication-title: J Hepatol doi: 10.1016/S0168-8278(12)60007-5 – volume: 102 start-page: 570 year: 2007 ident: 10.3350/cmh.2014.20.1.38_ref31 publication-title: Am J Gastroenterol doi: 10.1111/j.1572-0241.2006.01038.x – volume: 18 start-page: 41 year: 2012 ident: 10.3350/cmh.2014.20.1.38_ref4 publication-title: Korean J Hepatol doi: 10.3350/kjhep.2012.18.1.41 – volume: 38 start-page: 355 year: 2003 ident: 10.3350/cmh.2014.20.1.38_ref7 publication-title: J Gastroenterol doi: 10.1007/s005350300063 – volume: 132 start-page: 761 year: 2000 ident: 10.3350/cmh.2014.20.1.38_ref6 publication-title: Ann Intern Med doi: 10.7326/0003-4819-132-9-200005020-00023 – volume: 12 start-page: 7075 year: 2006 ident: 10.3350/cmh.2014.20.1.38_ref22 publication-title: World J Gastroenterol doi: 10.3748/wjg.v12.i44.7075 – volume: 18 start-page: 22 year: 2012 ident: 10.3350/cmh.2014.20.1.38_ref1 publication-title: Korean J Hepatol doi: 10.3350/kjhep.2012.18.1.22 – volume: 3 start-page: 108 year: 2009 ident: 10.3350/cmh.2014.20.1.38_ref33 publication-title: Gut Liver doi: 10.5009/gnl.2009.3.2.108 – volume: 52 start-page: 161 year: 2001 ident: 10.3350/cmh.2014.20.1.38_ref12 publication-title: Antiviral Res doi: 10.1016/S0166-3542(01)00181-4 – volume: 25 start-page: 1502 year: 1997 ident: 10.3350/cmh.2014.20.1.38_ref18 publication-title: Hepatology doi: 10.1002/hep.510250632 – volume: 128 start-page: 636 year: 2005 ident: 10.3350/cmh.2014.20.1.38_ref28 publication-title: Gastroenterology doi: 10.1053/j.gastro.2004.12.049 – volume: 58 start-page: 1662 year: 2009 ident: 10.3350/cmh.2014.20.1.38_ref26 publication-title: Gut doi: 10.1136/gut.2009.185074 – volume: 110 start-page: 363 year: 2011 ident: 10.3350/cmh.2014.20.1.38_ref16 publication-title: J Formos Med Assoc doi: 10.1016/S0929-6646(11)60054-5 – volume: 31 start-page: 66 year: 2011 ident: 10.3350/cmh.2014.20.1.38_ref29 publication-title: Liver Int doi: 10.1111/j.1478-3231.2010.02343.x – volume: 8 start-page: 458 year: 2010 ident: 10.3350/cmh.2014.20.1.38_ref32 publication-title: Clin Gastroenterol Hepatol doi: 10.1016/j.cgh.2010.01.022 – volume: 102 start-page: 1237 year: 2007 ident: 10.3350/cmh.2014.20.1.38_ref3 publication-title: Am J Gastroenterol doi: 10.1111/j.1572-0241.2007.01181.x – volume: 31 start-page: 1155 year: 2011 ident: 10.3350/cmh.2014.20.1.38_ref2 publication-title: Liver Int doi: 10.1111/j.1478-3231.2011.02545.x – volume: 41 start-page: 97 issue: Suppl 2 year: 1992 ident: 10.3350/cmh.2014.20.1.38_ref11 publication-title: Diabetes doi: 10.2337/diab.41.2.S97 – volume: 50 start-page: 1702 year: 2009 ident: 10.3350/cmh.2014.20.1.38_ref30 publication-title: Hepatology doi: 10.1002/hep.23206 – volume: 39 start-page: 195 year: 2009 ident: 10.3350/cmh.2014.20.1.38_ref15 publication-title: Hepatol Res doi: 10.1111/j.1872-034X.2008.00439.x – volume: 133 start-page: 611 year: 2003 ident: 10.3350/cmh.2014.20.1.38_ref9 publication-title: Swiss Med Wkly – reference: 3079540 - Atherosclerosis. 1987 Oct;67(2-3):261-7 – reference: 17131467 - World J Gastroenterol. 2006 Nov 28;12(44):7075-80 – reference: 20156586 - Clin Gastroenterol Hepatol. 2010 May;8(5):458-62 – reference: 17222321 - Am J Gastroenterol. 2007 Mar;102(3):570-6 – reference: 21745292 - Liver Int. 2011 Sep;31(8):1155-62 – reference: 11513192 - Am J Gastroenterol. 2001 Aug;96(8):2468-72 – reference: 21741004 - J Formos Med Assoc. 2011 Jun;110(6):363-71 – reference: 16871569 - Hepatology. 2006 Aug;44(2):335-40 – reference: 19695729 - J Hepatol. 2009 Dec;51(6):984-90 – reference: 20840397 - Liver Int. 2011 Jan;31(1):66-74 – reference: 10787379 - Ann Intern Med. 2000 May 2;132(9):761-2 – reference: 20234345 - Am J Gastroenterol. 2010 Sep;105(9):1970-7 – reference: 17977612 - J Hepatol. 2008 Jan;48(1):28-34 – reference: 12743775 - J Gastroenterol. 2003;38(4):355-60 – reference: 19231011 - J Hepatol. 2009 Apr;50(4):712-8 – reference: 8035505 - J Virol. 1994 Aug;68(8):5045-55 – reference: 17531012 - Am J Gastroenterol. 2007 Jun;102(6):1237-43 – reference: 22511899 - Korean J Hepatol. 2012 Mar;18(1):22-8 – reference: 19671541 - Gut. 2009 Dec;58(12):1662-9 – reference: 19845037 - Hepatology. 2009 Dec;50(6):1702-8 – reference: 22511902 - Korean J Hepatol. 2012 Mar;18(1):41-7 – reference: 15765399 - Gastroenterology. 2005 Mar;128(3):636-41 – reference: 18814931 - J Hepatol. 2008 Nov;49(5):831-44 – reference: 10347117 - Hepatology. 1999 Jun;29(6):1743-51 – reference: 22300466 - J Hepatol. 2012;56 Suppl 1:S56-65 – reference: 1526345 - Diabetes. 1992 Oct;41 Suppl 2:97-101 – reference: 14745667 - Swiss Med Wkly. 2003 Dec 13;133(45-46):611-8 – reference: 11672826 - Antiviral Res. 2001 Nov;52(2):161-71 – reference: 19054155 - Hepatol Res. 2009 Feb;39(2):195-9 – reference: 20431732 - Gut Liver. 2009 Jun;3(2):108-15 – reference: 9185775 - Hepatology. 1997 Jun;25(6):1502-6 |
| SSID | ssj0000702593 |
| Score | 2.1167924 |
| Snippet | Lipid profile and insulin resistance (IR) are associated with hepatitis C virus (HCV) and may predict the chronic hepatitis C (CHC) treatment response. The aim... Background/AimsLipid profile and insulin resistance (IR) are associated with hepatitis C virus (HCV) and may predict the chronic hepatitis C (CHC) treatment... Background/Aims: Lipid profile and insulin resistance (IR) are associated with hepatitis C virus (HCV) and may predictthe chronic hepatitis C (CHC) treatment... |
| SourceID | nrf doaj unpaywall pubmedcentral proquest pubmed crossref |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database Enrichment Source |
| StartPage | 38 |
| SubjectTerms | Adult Aged Antiviral Agents - pharmacology Antiviral Agents - therapeutic use Antiviral drugs Body mass index Cholesterol - blood Chronic hepatitis C Drug Therapy, Combination Female Genotype Hepacivirus - genetics Hepatitis C Hepatitis C, Chronic - drug therapy High density lipoprotein Humans Insulin Resistance Interferon-alpha - pharmacology Interferon-alpha - therapeutic use Lipid metabolism Lipid Metabolism - drug effects Male Middle Aged Original Polyethylene Glycols - pharmacology Polyethylene Glycols - therapeutic use Recombinant Proteins - pharmacology Recombinant Proteins - therapeutic use Ribavirin - therapeutic use Treatment Outcome Triglycerides - blood 내과학 |
| SummonAdditionalLinks | – databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Nb9NAEF2hHoAL4pvQghaJC0huYu_3ESqqglROVOpttbbXrVVnHTkOqD-j_5iZtWslAtELl0SOvZN453lnXnb2LSHvDSQZpXQ8WRSpTrjXMnEmqxINLE6LnFUsxQXOp9_lyRn_di7Ot7b6wpqwQR546Li5No4XVcUkr0ruZOYqyb3hmhcm9aWMYtsLbbbIVByDFcTyqLibASVIMpXpYY6SMbGYF0uchkjxL5XD9BCXpmzFpCjdD5EmdNXfss4_iycfbMLKXf9yTbMVmY4fk0djSkk_DbfyhNzz4Sm5fzpOmj8jNwAFOqyGpG1FV_7iuoEMs6QoFdFVvmsDdaGkXZ27n3VXBwooBMIcfUanSnQKB029qku69D1Ap6nXy9huLGenQNwxGQUUUbQxqO7SS4812329pkd0FHFdPydnx19-HJ0k404MSSG06ZPcQ17iF2nBczjmwinl01yAI4U0hYG4rzDueVYB55XcaemBKgGTEl4IBxnBC7IX2uBfEcoLxiHn1Eoxw0vhjQYsZ8xJ54Xjzs3I_NYXthhlynG3jMYCXUHvWfCeRe_Bi00t0zPyYWqxGiQ6_nHtZ3TvdB2Ka8cPAHJ2hJy9C3Iz8g7AYa-KOrbH94vWXnUWKMhXi4p3Cr7o4BY6dhwV1pZBNikUjOgcTEyn4XnGSRoXfLtZ2xQV8iDHlGDi5YC06ddmXAE9FGpG1A4Gd25n90yoL6NmOOoPswxsfpzQemdnvf4fnbVPHqLNoWzvgOz13ca_gTyuz9_GR_Y3bglFGg priority: 102 providerName: Directory of Open Access Journals – databaseName: ProQuest Central (subscription) dbid: BENPR link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwhV1db9MwFLVGJwEviG8KAxmJF5CyNvFnHhBi06aBtAohJu3Nchyni5YmIW1B-xn8Y-5N0rAKNF5apbGdOvfYPte-PibkTQwkI5WWB1MX6oB7LQMbR1mgwYvTImEZC3GD8-lMnpzxz-fifIfMNnthMKxy0ye2HXVaOZwjnzAYiYWC1sA_1N8DPDUKV1c3R2jY_miF9H0rMXaL7EaojDUiuwdHsy9fh1kXAHjUKfFG4CoEkYp0t3bJmJhO3AKXJ0KcatkP93HLyrWxqpX0hxGobLJ_sdG_gyrvrMvaXv20RXFtxDq-T-71VJN-7LDxgOz48iG5fdovpj8ivwAitNslSauM1n5-VQDzTClKSDSZb6qS2jKlTZ7YH3mTlxTeFDjSrS3pEKFO4aLI6zylC78CSBX5ctHm68PcKTj0SFIBXRTL6NR46YXHWO5VvqSHtBd3XT4mZ8dH3w5Pgv6EhsAJHa-CxANf8dPQ8QSuubBK-TARYGAhYxcDH1A4HnqWgS8sudXSgwsFHpbwQlhgCk_IqKxK_4xQ7hgHLqqVYjFPhY81YDxiVlovLLd2TCYbWxjXy5fjKRqFATcGrWfAegatBx8mNEyPydshR91Jd9yQ9gDNO6RD0e32h6qZm74NGx1b7rIMKpKl3MrIZpL7mGvu4tCnUo7JawCHuXR5mx-_55W5bAy4Jp8MKuEpeNDeBjqm7y2W5g-2oYjhNrRzXLyxpa_WSxOich5wTwlFPO2QNvzbiCtwG4UaE7WFwa3qbN8p84tWSxx1iVkEZb4b0Prfl_X85jq8IHcxdReot0dGq2btXwJzWyWv-ub4G4AGQnU priority: 102 providerName: ProQuest – databaseName: Unpaywall dbid: UNPAY link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1db9MwFLWgk4AXvscKAxmJF5DSNontOI9jYhpIGzxQqTxZTmKvUdMkStKh8S_4x9ybpNEKiI-XNE5st46Pc8-tr48JeRUCyUiEZs4sdqXDjBSODj3rSPDiJI9867u4wPnsXJzO2YcFX_SOYr0Nq3Ti9bKdxd-UWaGTaZnYKVxycLGvnEDqJtkTHLj3iOzNzz8dfcEd5ID6O17QbqbanUu-6OYlfZ_PsDwGcuHfKBN3gstRrtmhVq4frEte2d8xzV8DJm9v8lJffdVZds0andwjH7ft6IJQVpNNE03ibz9JPP57Q--Tuz0xpUcdkh6QGyZ_SG6d9VPvj8h3ABTt1lTSwtLSXFxlwFMTioITlTVVkVOdJ7RKI32ZVmlOAcvgdrc9T4d4dgqJLC3ThK5NAwDM0nrdluuD4im4_0hpAYsU6-i0e-nSYOR3k9b0mPZSsPVjMj959_n41On3c3BiLsPGiQywGzNzYxZBmnEdBMaNOMCBizAOgT0EaD2Nb8FzFkxLYcDhAn-MG8418Ip9MsqL3BwQymKfAXOVQeCHLOEmlDAiPF8LbbhmWo_JdNu7Ku7FznHPjUyB04N4UPCYFeIBDspVvhyT10OJshP6-EPetwiYIR9KdLcXoCtVP-KVDDWLrYWG2IRp4WkrmAmZZHHomkSIMXkJcFOrOG3L4-dFoVaVAkfmvULdvAC-6HALRtW_W2rlAyflAdgFBlUMt-GtgFM9OjfFplYu6uwBUxVQxZMOu8Ov9VgATiYPxiTYQfVOc3bv5OmyVR5HFWPfgzrfDPj_68N6-j-Zn5E7mOyC_A7JqKk25jmwviZ60Q_1H9omVj8 priority: 102 providerName: Unpaywall |
| Title | The impact of pegylated interferon and ribavirin combination treatment on lipid metabolism and insulin resistance in chronic hepatitis C patients |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/24757657 https://www.proquest.com/docview/3125577634 https://www.proquest.com/docview/1518815968 https://pubmed.ncbi.nlm.nih.gov/PMC3992328 https://www.e-cmh.org/upload/pdf/cmh-20-38.pdf https://doaj.org/article/89a4cff364fd4a62af64e9484c91ed66 https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART001859130 |
| UnpaywallVersion | publishedVersion |
| Volume | 20 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| ispartofPNX | Clinical and Molecular Hepatology, 2014, 20(1), , pp.38-46 |
| journalDatabaseRights | – providerCode: PRVAFT databaseName: Open Access Digital Library customDbUrl: eissn: 2287-285X dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0000702593 issn: 2287-285X databaseCode: KQ8 dateStart: 20120101 isFulltext: true titleUrlDefault: http://grweb.coalliance.org/oadl/oadl.html providerName: Colorado Alliance of Research Libraries – providerCode: PRVAON databaseName: DOAJ Directory of Open Access Journals customDbUrl: eissn: 2287-285X dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0000702593 issn: 2287-285X databaseCode: DOA dateStart: 19950101 isFulltext: true titleUrlDefault: https://www.doaj.org/ providerName: Directory of Open Access Journals – providerCode: PRVBFR databaseName: Free Medical Journals customDbUrl: eissn: 2287-285X dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0000702593 issn: 2287-285X databaseCode: DIK dateStart: 20120101 isFulltext: true titleUrlDefault: http://www.freemedicaljournals.com providerName: Flying Publisher – providerCode: PRVERR databaseName: KoreaMed Open Access customDbUrl: eissn: 2287-285X dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0000702593 issn: 2287-285X databaseCode: 5-W dateStart: 20120101 isFulltext: true titleUrlDefault: https://koreamed.org/journals providerName: Korean Association of Medical Journal Editors – providerCode: PRVAQN databaseName: PubMed Central customDbUrl: eissn: 2287-285X dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0000702593 issn: 2287-285X databaseCode: RPM dateStart: 20120101 isFulltext: true titleUrlDefault: https://www.ncbi.nlm.nih.gov/pmc/ providerName: National Library of Medicine – providerCode: PRVPQU databaseName: Health & Medical Collection customDbUrl: eissn: 2287-285X dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0000702593 issn: 2287-285X databaseCode: 7X7 dateStart: 20110301 isFulltext: true titleUrlDefault: https://search.proquest.com/healthcomplete providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Central customDbUrl: http://www.proquest.com/pqcentral?accountid=15518 eissn: 2287-285X dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0000702593 issn: 2287-285X databaseCode: BENPR dateStart: 20110301 isFulltext: true titleUrlDefault: https://www.proquest.com/central providerName: ProQuest – providerCode: PRVFZP databaseName: Scholars Portal Journals: Open Access customDbUrl: eissn: 2287-285X dateEnd: 20250430 omitProxy: true ssIdentifier: ssj0000702593 issn: 2287-285X databaseCode: M48 dateStart: 20120601 isFulltext: true titleUrlDefault: http://journals.scholarsportal.info providerName: Scholars Portal |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV1bb9MwGLXYJgEviOsojMpIvICUronvDwht06aB1GpCVCpPlpM4XbQ0KUkL9Gfwj_mcpIGKCnhplYvdOt9xvnNi5xihVwpIRswN9YaRLz1qJfeMChJPgoqTLCQJ8d0LzqMxv5zQD1M2_fV6dHsBq53Szq0nNSmzwfcv63fQ4d86xUnY8Diau1EF3z0hGfgDIvfQAeQp5RZyGLVkv74vC8jvtQtvADLBC0Qgm3HLnZVs5anazh-yT14mu5jonxMq76zyhVl_M1n2W7a6uI_utTQTnzS4eIBu2fwhuj1qB9IfoR8AD9y8IYmLBC_sbJ0B64yxs48oE1sWOTZ5jMs0NF_TMs0xIBNEdB1H3M1Ox7CRpYs0xnO7BDhlaTWvy7VT3DGIeUdQAVnY1dE48eJr6-ZxL9MKn-HW2LV6jCYX55_OLr12dQYvYlItvdACV7FDP6IhbFNmhLB-yCC4jKtIARcQLhdakoAO5tRIbkE-gbpiljEDLOEJ2s-L3D5FmEaEAg-VQhBFY2aVBHwHxHBjmaHG9NDxJhY6aq3L3QoamQYJ46KnIXraRQ8-tK-J7KHXXYlFY9vxl3NPXXi785zhdr2jKGe67b9aKkOjJIGGJDE1PDAJp1ZRSSPl25jzHnoJ4NA3UVqXd9-zQt-UGmTJe-1c8AT80NEGOnoDdE2AYTIBd3kKVXSHoY-7gRuT22JVad-55gHv5FDFYYO07t8GVIBkZKKHxBYGt5qzfSRPr2sfcedJTAKo802H1n9erGf_0c7n6K4r0szUO0L7y3JlXwB1W4Z9tCemoo8OTs_HVx_79QOQft1LYd9kfHXy-Sd0lUYY |
| linkProvider | Scholars Portal |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1fb9MwELemTWK8oPG_MMBI8ABS1iaxHedhQmxsatlaIbRJe_OcxOmipUmXtEz9GHwhPht3SRpWgcbTXlqliZ2kd767n33-HSHvfAgyIqGZ1QttaTEjhaV9J7YkoDjJAzd2bdzgPByJ_in7esbP1siv5V4YTKtc2sTKUEd5iHPkXRc8MfdgNLBP0ysLq0bh6uqyhIZuSitEuxXFWLOx48gsrgHClbuDLyDv945zeHCy37eaKgNWyKU_swIDPtf07JAFcMy49jxjBxwekgs_9MGneWjTjRsDnhNMS2EABgBK4IZzLbFqBLiADeYyH8Dfxt7B6Nv3dpYHBpRTM_86AE0sx3NkvVbqurzXDSe4HGLj1M6OvYNbZG74xqqEAHi8rIj_Ff3-ncS5Oc-menGt0_SGhzzcIg-a0JZ-rnXxIVkz2SNyb9gs3j8mP0Elab0rk-YxnZrxIoVIN6JIWVHEpsgzqrOIFkmgfyRFklGQDAD3SndomxFP4SBNpklEJ2YGKpwm5aRq16TV08KUGBSDNlPso2b_pRcGc8dnSUn3aUMmWz4hp3ciq6dkPcsz85xQFqLAwFx5rs8ibnwJY8pxtdCGa6Z1h3SXslBhQ5eOVTtSBbAJpadAegqlBx_KVq7skA9ti2lNFXLLtXso3vY6JPmufsiLsWpshpK-ZmEcw4vEEdPC0bFgxmeShb5tIiE65C0oh7oMk6o9fo9zdVkogEIDhcx7Htxoe6k6qrFOpfozlqCL9jTYFVws0pnJ56WykakPYl0BXTyrNa19Wod5AFO51yHeig6uvM7qmSy5qLjLkQfZdaDPj622_vfPenH7O7whm_2T4bE6HoyOXpL72LJOEtwm67Nibl5B1DgLXjdDk5Lzu7YGvwGOBXxr |
| linkToUnpaywall | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1db9MwFLWgk4AXvscKAxmJF5DSNontOI9jYhpIGzxQqTxZTmKvUdMkStKh8S_4x9ybpNEKiI-XNE5st46Pc8-tr48JeRUCyUiEZs4sdqXDjBSODj3rSPDiJI9867u4wPnsXJzO2YcFX_SOYr0Nq3Ti9bKdxd-UWaGTaZnYKVxycLGvnEDqJtkTHLj3iOzNzz8dfcEd5ID6O17QbqbanUu-6OYlfZ_PsDwGcuHfKBN3gstRrtmhVq4frEte2d8xzV8DJm9v8lJffdVZds0andwjH7ft6IJQVpNNE03ibz9JPP57Q--Tuz0xpUcdkh6QGyZ_SG6d9VPvj8h3ABTt1lTSwtLSXFxlwFMTioITlTVVkVOdJ7RKI32ZVmlOAcvgdrc9T4d4dgqJLC3ThK5NAwDM0nrdluuD4im4_0hpAYsU6-i0e-nSYOR3k9b0mPZSsPVjMj959_n41On3c3BiLsPGiQywGzNzYxZBmnEdBMaNOMCBizAOgT0EaD2Nb8FzFkxLYcDhAn-MG8418Ip9MsqL3BwQymKfAXOVQeCHLOEmlDAiPF8LbbhmWo_JdNu7Ku7FznHPjUyB04N4UPCYFeIBDspVvhyT10OJshP6-EPetwiYIR9KdLcXoCtVP-KVDDWLrYWG2IRp4WkrmAmZZHHomkSIMXkJcFOrOG3L4-dFoVaVAkfmvULdvAC-6HALRtW_W2rlAyflAdgFBlUMt-GtgFM9OjfFplYu6uwBUxVQxZMOu8Ov9VgATiYPxiTYQfVOc3bv5OmyVR5HFWPfgzrfDPj_68N6-j-Zn5E7mOyC_A7JqKk25jmwviZ60Q_1H9omVj8 |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+impact+of+pegylated+interferon+and+ribavirin+combination+treatment+on+lipid+metabolism+and+insulin+resistance+in+chronic+hepatitis+C+patients&rft.jtitle=Clinical+and+molecular+hepatology&rft.au=%EC%A0%95%ED%9D%AC%EC%9E%AC&rft.au=%EA%B9%80%EC%98%81%EC%84%9D&rft.au=%EA%B9%80%EC%83%81%EA%B7%A0&rft.au=%EC%9D%B4%EC%9C%A4%EB%82%98&rft.date=2014-03-01&rft.pub=%EB%8C%80%ED%95%9C%EA%B0%84%ED%95%99%ED%9A%8C&rft.issn=2287-2728&rft.eissn=2287-285X&rft.spage=38&rft.epage=46&rft_id=info:doi/10.3350%2Fcmh.2014.20.1.38&rft.externalDBID=n%2Fa&rft.externalDocID=oai_kci_go_kr_ARTI_492378 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2287-2728&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2287-2728&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2287-2728&client=summon |