Mannose receptor modulates macrophage polarization and allergic inflammation through miR-511-3p - Zhou, Yufeng; Do, Danh C.; Ishmael, Faoud T.; Squadrito, Mario Leonardo; Tang, Ho Man; Tang, Ho Lam; Hsu, Man-Hsun; Qiu, Lipeng; Li, Changjun; Zhang, Yongqing; Becker, Kevin G.; Wan, Mei; et al. (Journal of allergy and clinical immunology, 2018)
Keywords: Allergens - immunology; Allergies; Allergy and Immunology; Animals; Antigens; Asthma; Asthma - etiology; Asthma - metabolism; Asthma - pathology; Bone marrow; Cockroaches - immunology; Cytokines; Flow cytometry; Gene expression; Gene Expression Profiling; Gene Expression Regulation; Genetic Vectors - genetics; Green fluorescent protein; Helper cells; Hypersensitivity; Hypersensitivity - etiology; Hypersensitivity - metabolism; Hypersensitivity - pathology; Immunoglobulin E; Inflammation; Inner city; Laboratories; Lectins, C-Type - metabolism; Lungs; Lymphocytes T; macrophage; Macrophage Activation - genetics; Macrophage Activation - immunology; Macrophages; Macrophages - immunology; Macrophages - metabolism; Macrophages, Alveolar - immunology; Macrophages, Alveolar - metabolism; Mannose; Mannose Receptor; Mannose-Binding Lectins - metabolism; Membrane Glycoproteins - genetics; Membrane Glycoproteins - metabolism; Mice; Mice, Knockout; MicroRNAs; MicroRNAs - genetics; Microscopy; miR-511-3p; Models, Biological; Plasma levels; Pneumonia - etiology; Pneumonia - metabolism; Pneumonia - pathology; Polarization; Receptors, Cell Surface - genetics; Receptors, Cell Surface - metabolism; Receptors, Immunologic; RNA Interference; Rodents; PAS; M-CSF; ROCK2; CLR; LV; BM; LTBP1; GFP; FITC; FDR; MRC1; Mannose receptor; miRNA; qPCR; PTGDS; WT; SSC; miR-511-3p; AF; H&E; macrophage; asthma; BAL; CMV; AAV; CRE; TLR4; DC; CEBPA; Cockroach extract; Auto-fluorescence; C-type lectin-like domains; Bronchoalveolar lavage; CCAAT/Enhancer Binding Protein Alpha; MiR-511-3p; C-type lectin receptor; Rho Associated Coiled-Coil Containing Protein Kinase 2; Prostaglandin D2 Synthase; False Discovery Rate; Adeno-associated virus