Orienting Fate: Spatial Regulation of Neurogenic Divisions

Cleavage plane orientation has been thought to govern the fate of neural stem cell progeny, but supporting evidence in the neocortex has been sparse. A new study by Postiglione et al. in this issue of Neuron shows that mouse Inscuteable-mediated control of cleavage plane orientation regulates the ou...

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Published inNeuron (Cambridge, Mass.) Vol. 72; no. 2; pp. 191 - 193
Main Authors Wang, Xiaoqun, Lui, Jan H., Kriegstein, Arnold R.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 20.10.2011
Elsevier Limited
Subjects
Animals
Cell cycle
Cell Cycle Proteins - metabolism
Cell division
Cell Lineage - physiology
Cell Polarity - physiology
Evolution
Insects
Neocortex - growth & development
Nervous system
Neurogenesis
Neurogenesis - physiology
Neurons
Neurons - metabolism
Rodents
Spindle Apparatus - metabolism
Stem cells
Studies
Symmetry
Online AccessGet full text
ISSN0896-6273
1097-4199
1097-4199
DOI10.1016/j.neuron.2011.10.003

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Abstract Cleavage plane orientation has been thought to govern the fate of neural stem cell progeny, but supporting evidence in the neocortex has been sparse. A new study by Postiglione et al. in this issue of Neuron shows that mouse Inscuteable-mediated control of cleavage plane orientation regulates the output of neural progenitor cells.
AbstractList Cleavage plane orientation has been thought to govern the fate of neural stem cell progeny, but supporting evidence in the neocortex has been sparse. A new study shows that mouse Inscuteable-mediated control of cleavage plane orientation regulates the output of neural progenitor cells.
Cleavage plane orientation has been thought to govern the fate of neural stem cell progeny, but supporting evidence in the neocortex has been sparse. A new study by Postiglione et al. in this issue ofNeuronshows that mouse Inscuteable-mediated control of cleavage plane orientation regulates the output of neural progenitor cells.
Cleavage plane orientation has been thought to govern the fate of neural stem cell progeny, but supporting evidence in the neocortex has been sparse. A new study by Postiglione et al. in this issue of Neuron shows that mouse Inscuteable-mediated control of cleavage plane orientation regulates the output of neural progenitor cells.Cleavage plane orientation has been thought to govern the fate of neural stem cell progeny, but supporting evidence in the neocortex has been sparse. A new study by Postiglione et al. in this issue of Neuron shows that mouse Inscuteable-mediated control of cleavage plane orientation regulates the output of neural progenitor cells.
Cleavage plane orientation has been thought to govern the fate of neural stem cell progeny, but supporting evidence in the neocortex has been sparse. A new study by Postiglione et al. in this issue of Neuron shows that mouse Inscuteable-mediated control of cleavage plane orientation regulates the output of neural progenitor cells.
Cleavage plane orientation has been thought to govern the fate of neural stem cell progeny, but supporting evidence in the neocortex has been sparse. A new study by Postiglione et al. in this issue of Neuron shows that mouse Inscuteable-mediated control of cleavage plane orientation regulates the output of neural progenitor cells.
Author Kriegstein, Arnold R.
Wang, Xiaoqun
Lui, Jan H.
AuthorAffiliation 2 Department of Neurology, University of California San Francisco, 35 Medical Center Way, San Francisco, California 94143, USA
1 Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, 35 Medical Center Way, San Francisco, California 94143, USA
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Snippet Cleavage plane orientation has been thought to govern the fate of neural stem cell progeny, but supporting evidence in the neocortex has been sparse. A new...
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SubjectTerms Animals
Cell cycle
Cell Cycle Proteins - metabolism
Cell division
Cell Lineage - physiology
Cell Polarity - physiology
Evolution
Insects
Neocortex - growth & development
Nervous system
Neurogenesis
Neurogenesis - physiology
Neurons
Neurons - metabolism
Rodents
Spindle Apparatus - metabolism
Stem cells
Studies
Symmetry
Title Orienting Fate: Spatial Regulation of Neurogenic Divisions
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