血压和心率对颈动脉管壁切应力影响的初步研究
目的研究血压、心率对颈总动脉管壁切应力（wall shear stress，WSS）的影响。方法16例健康志愿者的双侧颈动脉分别行磁共振（magnetic resonance，MR）扫描，在颈动脉分叉部位下2cm颈总动脉平面上，把颈总动脉壁平均分为24等份，利用相位对比MR成像和三维抛物面模型拟合的方法，计算每个空间位置一个心动周期内的平均WSS以及空间位置上最小的WSS。观察收缩压、舒张压、平均动脉压、心率对颈功脉血流动力学参数的影响。结果16例健康志愿者的52条血管中，有5条血管因伪影排除在本研究之外。对剩下的29条血管进行分析，无论是双侧颈动脉，还是左侧或右侧颈动脉，平均WSS及空间位置...
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| Published in | 中国卒中杂志 Vol. 7; no. 6; pp. 461 - 465 |
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| Main Author | |
| Format | Journal Article |
| Language | Chinese |
| Published |
首都医科大学附属北京天坛医院神经内科,0北京,110005%首都医科大学生物医学工程学院%首都医科大学附属北京天坛医院神经影像中心
2012
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1673-5765 |
| DOI | 10.3969/j.issn.1673-5765.2012.06.007 |
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| Abstract | 目的研究血压、心率对颈总动脉管壁切应力（wall shear stress，WSS）的影响。方法16例健康志愿者的双侧颈动脉分别行磁共振（magnetic resonance，MR）扫描，在颈动脉分叉部位下2cm颈总动脉平面上，把颈总动脉壁平均分为24等份，利用相位对比MR成像和三维抛物面模型拟合的方法，计算每个空间位置一个心动周期内的平均WSS以及空间位置上最小的WSS。观察收缩压、舒张压、平均动脉压、心率对颈功脉血流动力学参数的影响。结果16例健康志愿者的52条血管中，有5条血管因伪影排除在本研究之外。对剩下的29条血管进行分析，无论是双侧颈动脉，还是左侧或右侧颈动脉，平均WSS及空间位置上最低WSS-b收缩压、舒张压、平均动脉压、心率均无明显相关性（P〉O．05）。结论健康志愿者玩邑动脉平均WSS和最低WSS与血、心率无明显相关。 |
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| AbstractList | R323.1; 目的 研究血压、心率对颈总动脉管壁切应力(wall shear stress,WSS)的影响.方法 16例健康志愿者的双侧颈动脉分别行磁共振(magnetic resonance,MR)扫描,在颈动脉分叉部位下2 cm颈总动脉平面上,把颈总动脉壁平均分为24等份,利用相位对比MR成像和三维抛物面模型拟合的方法,计算每个空间位置一个心动周期内的平均WSS以及空间位置上最小的WSS.观察收缩压、舒张压、平均动脉压、心率对颈动脉血流动力学参数的影响.结果 16例健康志愿者的32条血管中,有3条血管因伪影排除在本研究之外.对剩下的29条血管进行分析,无论是双侧颈动脉,还是左侧或右侧颈动脉,平均WSS及空间位置上最低WSS与收缩压、舒张压、平均动脉压、心率均无明显相关性(P＞0.05).结论 健康志愿者颈总动脉平均WSS和最低WSS与血压、心率无明显相关. 目的研究血压、心率对颈总动脉管壁切应力（wall shear stress，WSS）的影响。方法16例健康志愿者的双侧颈动脉分别行磁共振（magnetic resonance，MR）扫描，在颈动脉分叉部位下2cm颈总动脉平面上，把颈总动脉壁平均分为24等份，利用相位对比MR成像和三维抛物面模型拟合的方法，计算每个空间位置一个心动周期内的平均WSS以及空间位置上最小的WSS。观察收缩压、舒张压、平均动脉压、心率对颈功脉血流动力学参数的影响。结果16例健康志愿者的52条血管中，有5条血管因伪影排除在本研究之外。对剩下的29条血管进行分析，无论是双侧颈动脉，还是左侧或右侧颈动脉，平均WSS及空间位置上最低WSS-b收缩压、舒张压、平均动脉压、心率均无明显相关性（P〉O．05）。结论健康志愿者玩邑动脉平均WSS和最低WSS与血、心率无明显相关。 |
| Author | 秦海强 赵性泉 周萍 隋滨滨 王拥军 |
| AuthorAffiliation | 首都医科大学附属北京天坛医院神经内科,北京100050 首都医科大学生物医学工程学院 首都医科大学附属北京天坛医院神经影像中心 |
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| Author_FL | QIN Hai-Qiang ZHAO Xing-Quan ZHOU Ping SUI Bin-Bin WANG Yong-Jun |
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| Author_xml | – sequence: 1 fullname: 秦海强 赵性泉 周萍 隋滨滨 王拥军 |
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| ClassificationCodes | R323.1 |
| ContentType | Journal Article |
| Copyright | Copyright © Wanfang Data Co. Ltd. All Rights Reserved. |
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| DocumentTitleAlternate | Preliminary Study for Association of Blood Pressure and Heart Rate on Carotid Hemodynamics |
| DocumentTitle_FL | Preliminary Study for Association of Blood Pressure and Heart Rate on Carotid Hemodynamics |
| EndPage | 465 |
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| Issue | 6 |
| Keywords | 心率 血压 颈动脉 血流动力学 |
| Language | Chinese |
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| Notes | 11-5434/R Objective To study the effect of blood pressure and heart rate on the hemodynamics of common carotid artery（CCA）. Methods Sixteen healthy volunteers were studied. Wall shear stress（WSS） values localized at CCA 2 cm below the bifurcation were calculated with cine phase-contrast magnetic resonance（MR） imaging combined three-dimensional paraboloid（3DP） model. On the spatial distribution, carotid wall was divided by 24 equal parts. Calculate the mean WSS in a cardiac cycle on the each part, and choose the minimal WSS value. Then we observed the effect of systolic pressure, diastolic pressure, mean arterial pressure, or heart rate on the average WSS and minimal WSS. Results Total 32 carotid arteries of 16 health volunteers were examined, in which 3 carotid arteries were excluded because of uninterpretable high-resolution magnetic resonance imaging（MRI） findings. In the remaining 29 common carotid arteries analyzed, the average WSS and the minimal WSS during a cardiac cycle on the spatial distribution have |
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| PublicationTitle | 中国卒中杂志 |
| PublicationTitleAlternate | Chinese Journal of Stroke |
| PublicationTitle_FL | Chinese Journal of Stroke |
| PublicationYear | 2012 |
| Publisher | 首都医科大学附属北京天坛医院神经内科,0北京,110005%首都医科大学生物医学工程学院%首都医科大学附属北京天坛医院神经影像中心 |
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| Snippet | 目的研究血压、心率对颈总动脉管壁切应力（wall shear stress，WSS）的影响。方法16例健康志愿者的双侧颈动脉分别行磁共振（magnetic resonance，MR）扫描，在颈动脉分叉部... R323.1; 目的 研究血压、心率对颈总动脉管壁切应力(wall shear stress,WSS)的影响.方法 16例健康志愿者的双侧颈动脉分别行磁共振(magnetic resonance,MR)扫描,在颈动脉分叉... |
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| StartPage | 461 |
| SubjectTerms | 心率 血压 血流动力学 颈动脉 |
| Title | 血压和心率对颈动脉管壁切应力影响的初步研究 |
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