Multivariate Gaussian Bayes classifier with limited data for segmentation of clean and contaminated regions in the small bowel capsule endoscopy images

• Published in: PloS one Vol. 20; no. 3; p. e0315638
• Main Authors: Sadeghi, Vahid, Mehridehnavi, Alireza, Behdad, Maryam, Vard, Alireza, Omrani, Mina, Sharifi, Mohsen, Sanahmadi, Yasaman, Teyfouri, Niloufar
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 07.03.2025; Public Library of Science (PLoS)
• Subjects: Adaptability; Algorithms; Annotations; Bayes Theorem; Capsule Endoscopy - methods; Computer vision; Computers; Conditional probability; Covariance matrix; Datasets; Endoscopy; Evaluation; Gastroenterology; Gaussian processes; Humans; Image Processing, Computer-Assisted - methods; Image segmentation; Innovations; Intestine; Intestine, Small; Intestine, Small - diagnostic imaging; Medical examination; Methods; Normal Distribution; Performance evaluation; Pixels; ROC Curve; Small intestine; Statistical analysis; Statistical models; Visualization; Wavelet transforms; Iran
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0315638

A considerable amount of undesirable factors in the wireless capsule endoscopy (WCE) procedure hinder the proper visualization of the small bowel and take gastroenterologists more time to review. Objective quantitative assessment of different bowel preparation paradigms and saving the physician reviewing time motivated us to present an automatic low-cost statistical model for automatically segmenting of clean and contaminated regions in the WCE images. In the model construction phase, only 20 manually pixel-labeled images have been used from the normal and reduced mucosal view classes of the Kvasir capsule endoscopy dataset. In addition to calculating prior probability, two different probabilistic tri-variate Gaussian distribution models (GDMs) with unique mean vectors and covariance matrices have been fitted to the concatenated RGB color pixel intensity values of clean and contaminated regions separately. Applying the Bayes rule, the membership probability of every pixel of the input test image to each of the two classes is evaluated. The robustness has been evaluated using 5 trials; in each round, from the total number of 2000 randomly selected images, 20 and 1980 images have been used for model construction and evaluation modes, respectively. Our experimental results indicate that accuracy, precision, specificity, sensitivity, area under the receiver operating characteristic curve (AUROC), dice similarity coefficient (DSC), and intersection over union (IOU) are 0.89 ± 0.07, 0.91 ± 0.07, 0.73 ± 0.20, 0.90 ± 0.12, 0.92 ± 0.06, 0.92 ± 0.05 and 0.86 ± 0.09, respectively. The presented scheme is easy to deploy for objectively assessing small bowel cleansing score, comparing different bowel preparation paradigms, and decreasing the inspection time. The results from the SEE-AI project dataset and CECleanliness database proved that the proposed scheme has good adaptability.