自噬在缺血性卒中后的作用
Autophagy is an important way to remove the aging protein and damaged organelles. As a subtype of cell death, autophagy plays an important role in pathological and physiological conditions. There indeed is an autophagic phenomenon after ischemic insult in brain. Discussing the autophagy activation p...
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| Published in | 中国卒中杂志 Vol. 8; no. 4; pp. 311 - 315 |
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| Main Author | |
| Format | Journal Article |
| Language | Chinese |
| Published |
100050 北京首都医科大学附属北京友谊医院神经内科
2013
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1673-5765 |
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| Abstract | Autophagy is an important way to remove the aging protein and damaged organelles. As a subtype of cell death, autophagy plays an important role in pathological and physiological conditions. There indeed is an autophagic phenomenon after ischemic insult in brain. Discussing the autophagy activation pathways and how to evaluate it in quality and quantity will be helpful to figure out the role of autophay after ischemic stroke. |
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| AbstractList | Autophagy is an important way to remove the aging protein and damaged organelles. As a subtype of cell death, autophagy plays an important role in pathological and physiological conditions. There indeed is an autophagic phenomenon after ischemic insult in brain. Discussing the autophagy activation pathways and how to evaluate it in quality and quantity will be helpful to figure out the role of autophay after ischemic stroke. 自噬是机体清除过量、老化蛋白质及受损细胞器的重要途径。作为细胞死亡的一种形式，自噬在病理、生理条件下均具有重要作用。缺血性卒中后存在明确的自噬现象。了解自噬激活途径及调控位点，对其进行定位、定性以及定量检测，有助于理解自噬在缺血性卒中发生、发展过程中的作用。 |
| Author | 孙金梅 张拥波 李继梅 |
| AuthorAffiliation | 首都医科大学附属北京友谊医院神经内科,北京100050 |
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| DocumentTitleAlternate | Autophagy after lschemic Stroke |
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| Keywords | 缺血性卒中 自噬 坏死 Ischemic stroke 凋亡 Autophagy Apoptosis Necrosis |
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| Notes | 11-5434/R SUN Jin-Mei, ZHANG Yong-Bo, LI Ji-Mei.（ Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China） Autophagy is an important way to remove the aging protein and damaged organelles As a subtype of cell death, autophagy plays an important role in pathological and physiological conditions. There indeed is an autophagic phenomenon after ischemic insult in brain. Discussing the autophagy activation pathways and how to evaluate it in quality and quantity will be helpful to figure out the role of autophay after ischemic stroke. Autophagy; lscbemic stroke; Apoptosis; Necrosis |
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| PublicationTitleAlternate | Chinese Journal of Stroke |
| PublicationTitle_FL | Chinese Journal of Stroke |
| PublicationYear | 2013 |
| Publisher | 100050 北京首都医科大学附属北京友谊医院神经内科 |
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| Snippet | 自噬是机体清除过量、老化蛋白质及受损细胞器的重要途径。作为细胞死亡的一种形式，自噬在病理、生理条件下均具有重要作用。缺血性卒中后存在明确的自噬现象。了解自噬激活途径... Autophagy is an important way to remove the aging protein and damaged organelles. As a subtype of cell death, autophagy plays an important role in pathological... |
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| SubjectTerms | 凋亡 坏死 缺血性卒中 自噬 |
| Title | 自噬在缺血性卒中后的作用 |
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