渗透性表面面积指数对幕上脑出血早期血肿扩大的预测研究
目的探讨渗透性表面面积指数（permeability—surfaceareaproductindex，PSI）预测幕上脑出血早期血肿扩大的敏感程度。方法连续入组2007年9月～2012年4月首都医科大学附属北京天坛医院急性幕上脑出血患者40例（发病6h内），比较入院时及发病24h时的计算机断层扫描（computedtomography，CT）的血肿体积，根据血肿体积增加是否大于33％者分为血肿扩大组和未扩大组。通过计算机断层扫描血管成像（computedtomographyangiography，CTA）的点征和灌注cT的渗透性表面面积及PSI，比较PSI预测血肿扩大的灵敏度及特异度。结果血肿...
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| Published in | 中国卒中杂志 Vol. 8; no. 5; pp. 334 - 339 |
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| Main Author | |
| Format | Journal Article |
| Language | Chinese |
| Published |
102206 北京北大国际医院神经内科%首都医科大学附属北京天坛医院神经内科
2013
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1673-5765 |
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| Abstract | 目的探讨渗透性表面面积指数（permeability—surfaceareaproductindex，PSI）预测幕上脑出血早期血肿扩大的敏感程度。方法连续入组2007年9月～2012年4月首都医科大学附属北京天坛医院急性幕上脑出血患者40例（发病6h内），比较入院时及发病24h时的计算机断层扫描（computedtomography，CT）的血肿体积，根据血肿体积增加是否大于33％者分为血肿扩大组和未扩大组。通过计算机断层扫描血管成像（computedtomographyangiography，CTA）的点征和灌注cT的渗透性表面面积及PSI，比较PSI预测血肿扩大的灵敏度及特异度。结果血肿扩大的发生率为45％，血肿扩大组水肿组织PSI为（2．60±0．51）高于未扩大组（2．27±0．34）（P=0．040）；水肿组织Ps畛断血肿扩大的灵敏度为88．89％，特异度为68．18％。结论脑出血急性期血肿扩大后PsI增加，Psi预测幕上脑出血急性期血肿扩大敏感性高。 |
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| AbstractList | 目的探讨渗透性表面面积指数(permeability-surface area product index,PSI)预测幕上脑出血早期血肿扩大的敏感程度.方法连续入组2007年9月~2012年4月首都医科大学附属北京天坛医院急性幕上脑出血患者40例(发病6 h内),比较入院时及发病24 h时的计算机断层扫描(computed tomography,CT)的血肿体积,根据血肿体积增加是否大于33%者分为血肿扩大组和未扩大组.通过计算机断层扫描血管成像(computed tomography angiography,CTA)的点征和灌注CT的渗透性表面面积及PSI,比较PSI预测血肿扩大的灵敏度及特异度.结果血肿扩大的发生率为45%,血肿扩大组水肿组织PSI为(2.600.51)高于未扩大组(2.270.34)(P=0.040);水肿组织PSI诊断血肿扩大的灵敏度为88.89%,特异度为68.18%.结论脑出血急性期血肿扩大后PSI增加,PSI预测幕上脑出血急性期血肿扩大敏感性高. 目的探讨渗透性表面面积指数（permeability—surfaceareaproductindex，PSI）预测幕上脑出血早期血肿扩大的敏感程度。方法连续入组2007年9月～2012年4月首都医科大学附属北京天坛医院急性幕上脑出血患者40例（发病6h内），比较入院时及发病24h时的计算机断层扫描（computedtomography，CT）的血肿体积，根据血肿体积增加是否大于33％者分为血肿扩大组和未扩大组。通过计算机断层扫描血管成像（computedtomographyangiography，CTA）的点征和灌注cT的渗透性表面面积及PSI，比较PSI预测血肿扩大的灵敏度及特异度。结果血肿扩大的发生率为45％，血肿扩大组水肿组织PSI为（2．60±0．51）高于未扩大组（2．27±0．34）（P=0．040）；水肿组织Ps畛断血肿扩大的灵敏度为88．89％，特异度为68．18％。结论脑出血急性期血肿扩大后PsI增加，Psi预测幕上脑出血急性期血肿扩大敏感性高。 |
| Abstract_FL | Objective To investigate the sensitivity between permeability-surface area product index and hematoma expansion in acute intracerebral hemorrhage. Methods Forty patients with acute intracerebral hemorrhage(onset within 6 hours) who hospitalized in Beijing Tiantan Hospital from September 2007 to April 2012 were included in this study. Computed tomography(CT) perfusion was taken within 6 hours after the patients’ symptom onset, and CT scan was rechecked at 24 hours after the patients’ symptom onset. The correlation between permeability-surface area product and hematoma expansion was evaluated. Results The incidence rate of hematoma enlargement was 45%. The permeability-surface area product index(PSI)(2.60? ?0.51) of the edema tissue of patients with hematoma enlargement was bigger than those without(2.27? ?0.34)(P=0.040). In the diagnosis of hematoma enlargement, the sensitivity of PSI of edema was 88.89%, the specificity was 68.18%. Conclusion In the acute phase of cerebral hemorrhage, PSI is increased, and PSI is very sensitive in prediction of the occurrence of hematoma enlargement. |
| Author | 王玮婧 赵性泉 |
| AuthorAffiliation | 北大国际医院神经内科,北京102206 首都医科大学附属北京天坛医院神经内科 |
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| Keywords | Permeability-surface area product Computed tomography perfusion Cerebral hemorrhage 脑出血 急性期 计算机断层扫描灌注显像 Hematoma expansion 渗透性表面面积 Acute phase 血肿 |
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| Notes | 11-5434/R Objective To investigate the sensitivity between permeability-surface area product index and hematoma expansion in acute intracerebral hemorrhage. Methods Forty patients with acute intracerebral hemorrhage（onset within 6 hours） who hospitalized in Beijing Tiantan Hospital from September 2007 to April 2012 were included in this study. Computed tomography（CT） perfusion was taken within 6 hours after the patients＇ symptom onset, and CT scan was rechecked at 24 hours after the patients＇ symptom onset. The correlation between permeability-surface area product and hematoma expansion was evaluated. Results The incidence rate of hematoma enlargement was 45%. The permeability-surface area product index（PSI）（2.60±0.51） of the edema tissue of patients with hematoma enlargement was bigger than those without（2.27±0.34）（P=0.040）. In the diagnosis of hematoma enlargement, the sensitivity of PSI of edema was 88.89%, the specificity was 68.18%. Conclusion In the acute phase of cerebral hemorrhage, PSI is increased, a |
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| Publisher | 102206 北京北大国际医院神经内科%首都医科大学附属北京天坛医院神经内科 |
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| Snippet | 目的探讨渗透性表面面积指数（permeability—surfaceareaproductindex，PSI）预测幕上脑出血早期血肿扩大的敏感程度。方法连续入组2007年9月～2012年4月首都医科大学附属北... 目的探讨渗透性表面面积指数(permeability-surface area product index,PSI)预测幕上脑出血早期血肿扩大的敏感程度.方法连续入组2007年9月~2012年4月首都医科大学附属北京... |
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| SubjectTerms | 急性期 渗透性表面面积 脑出血 血肿 计算机断层扫描灌注显像 |
| Title | 渗透性表面面积指数对幕上脑出血早期血肿扩大的预测研究 |
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