TSC2 modulates actin cytoskeleton and focal adhesion through TSC1-binding domain and the Rac1 GTPase - Goncharova, Elena; Goncharov, Dmitry; Noonan, Daniel; Krymskaya, Vera P (The Journal of cell biology, 2004)
Keywords: 3T3 Cells; Actins; Actins - metabolism; Adhesion; Animals; Antibodies; Cell adhesion & migration; Cell Adhesion - drug effects; Cell Adhesion - physiology; Cell Line, Tumor; Cell motility; Cellular biology; Cytoskeleton - metabolism; Cytoskeleton - physiology; Deregulation; Down-Regulation; Fibers; Focal adhesions; Gene expression regulation; Mice; Plasmids; Proteins; Proteins - antagonists & inhibitors; Proteins - genetics; Proteins - metabolism; rac1 GTP-Binding Protein - antagonists & inhibitors; rac1 GTP-Binding Protein - metabolism; Rats; Renovations; Repressor Proteins - genetics; Repressor Proteins - metabolism; Repressor Proteins - pharmacology; rho GTP-Binding Proteins - antagonists & inhibitors; rho GTP-Binding Proteins - metabolism; RNA, Small Interfering - genetics; Small interfering RNA; Stress fibers; Tuberous Sclerosis Complex 1 Protein; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins