周围型肺癌CT征象与p53蛋白异常表达关系的研究
目的：探讨边缘型肺癌CT征象与肺癌组织中p53基因异常表达的关系。方法 临床选择肺占位性病变患者52例，行常规CT扫描。采用免疫组化法检测术后肺组织标本p53基因的表达。结果 p53蛋白阳性表达与肺癌分化程度、肺癌瘤体大小、肺癌瘤体形态、胸膜凹陷和淋巴结转移等CT征象有密切关系。结论 p53基因突变代表肺癌的生物学行为，并在一定程度上影响肺癌的形态学特征，与CT征象有密切关系。...
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| Published in | Zhongguo fei ai za zhi Vol. 5; no. 1; pp. 18 - 20 |
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| Main Author | |
| Format | Journal Article |
| Language | Chinese |
| Published |
150040,哈尔滨医科大学第三临床医学院影像诊断科%150040,哈尔滨医科大学克山病研究所
2002
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1009-3419 1999-6187 |
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| Abstract | 目的：探讨边缘型肺癌CT征象与肺癌组织中p53基因异常表达的关系。方法 临床选择肺占位性病变患者52例，行常规CT扫描。采用免疫组化法检测术后肺组织标本p53基因的表达。结果 p53蛋白阳性表达与肺癌分化程度、肺癌瘤体大小、肺癌瘤体形态、胸膜凹陷和淋巴结转移等CT征象有密切关系。结论 p53基因突变代表肺癌的生物学行为，并在一定程度上影响肺癌的形态学特征，与CT征象有密切关系。 |
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| AbstractList | R734.2; 目的探讨边缘型肺癌CT征象与肺癌组织中p53基因异常表达的关系.方法临床选择肺占位性病变患者52例,行常规CT扫描.采用免疫组化法检测术后肺组织标本p53基因的表达.结果 p53蛋白阳性表达与肺癌分化程度、肺癌瘤体大小、肺癌瘤体形态、胸膜凹陷和淋巴结转移等CT征象有密切关系.结论 p53基因突变代表肺癌的生物学行为,并在一定程度上影响肺癌的形态学特征,与CT征象有密切关系. 目的：探讨边缘型肺癌CT征象与肺癌组织中p53基因异常表达的关系。方法 临床选择肺占位性病变患者52例，行常规CT扫描。采用免疫组化法检测术后肺组织标本p53基因的表达。结果 p53蛋白阳性表达与肺癌分化程度、肺癌瘤体大小、肺癌瘤体形态、胸膜凹陷和淋巴结转移等CT征象有密切关系。结论 p53基因突变代表肺癌的生物学行为，并在一定程度上影响肺癌的形态学特征，与CT征象有密切关系。 |
| Author | 刘晓杰 张卫星 等 |
| AuthorAffiliation | 哈尔滨医科大学第三临床医学院影像诊断科150040 哈尔滨医科大学克山病研究所 |
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| DocumentTitle_FL | The relationship between the CT signs and p53 abnormal expression in peripheral lung cancer |
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| Snippet | 目的：探讨边缘型肺癌CT征象与肺癌组织中p53基因异常表达的关系。方法 临床选择肺占位性病变患者52例，行常规CT扫描。采用免疫组化法检测术后肺组织标本p53基因的表达。结果... R734.2; 目的探讨边缘型肺癌CT征象与肺癌组织中p53基因异常表达的关系.方法临床选择肺占位性病变患者52例,行常规CT扫描.采用免疫组化法检测术后肺组织标本p53基因的表达.... |
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| SubjectTerms | CT征象 p53蛋白 周围型肺癌 异常表达 |
| Title | 周围型肺癌CT征象与p53蛋白异常表达关系的研究 |
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