New genetic predictors for abacavir tolerance in HLA-B57:01 positive individuals - Pavlos, Rebecca; Deshpande, Pooja; Chopra, Abha; Leary, Shay; Strautins, Kaija; Nolan, David; Thorborn, Daren; Shaefer, Mark; Rauch, Andri; Dunn, David; Montaner, Julio; Rachlis, Anita; et al. (Human immunology, 2020)
Keywords: Abacavir hypersensitivity syndrome; Allergens - immunology; Aminopeptidases - genetics; Anti-HIV Agents - immunology; Anti-HIV Agents - therapeutic use; Dideoxynucleosides - adverse effects; Dideoxynucleosides - immunology; Dideoxynucleosides - therapeutic use; Drug Hypersensitivity Syndrome - etiology; Drug Hypersensitivity Syndrome - genetics; Drug-Related Side Effects and Adverse Reactions - genetics; Endoplasmic reticulum aminopeptidase 1; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; HIV Infections - complications; HIV Infections - drug therapy; HIV-1 - physiology; HLA-B Antigens - genetics; Human leukocyte antigen; Humans; Lipopolysaccharide Receptors - genetics; Male; Minor Histocompatibility Antigens - genetics; Phenotype; Retrospective Studies; aa; IM-ADR; PREDICT-1; sCD14; PT; ADH; ERAP1; MHC; Endoplasmic reticulum aminopeptidase 1; Abacavir hypersensitivity syndrome; MAF; KIR; NPV; Human leukocyte antigen; PPV; LD; SNPs; CD14; ERAP; HLA; NK; ABC HSS