A Serine Palmitoyltransferase Inhibitor Blocks Hepatitis C Virus Replication in Human Hepatocytes - Katsume, Asao; Tokunaga, Yuko; Hirata, Yuichi; Munakata, Tsubasa; Saito, Makoto; Hayashi, Hitohisa; Okamoto, Koichi; Ohmori, Yusuke; Kusanagi, Isamu; Fujiwara, Shinya; Tsukuda, Takuo; Aoki, Yuko; et al. (Gastroenterology (New York, N.Y. 1943), 2013)
Keywords: Animals; Antiviral Agents - pharmacology; DAAs; Direct-Acting Antiviral Agents; Drug; Gastroenterology and Hepatology; HCV Lifecycle; Hepacivirus - classification; Hepacivirus - drug effects; Hepacivirus - genetics; Hepatocytes - virology; Humans; Mice; RNA, Viral - analysis; Serine C-Palmitoyltransferase - antagonists & inhibitors; Virus Replication - drug effects; DAAs; Drug; HCV Lifecycle; Direct-Acting Antiviral Agents; DAA; SPT; IC50; RBV; PEG-IFN; cDNA; HCV; PCR; 50% inhibitory concentration; IC 50; pegylated interferon alfa-2a; ribavirin; serine palmitoyltransferase; complementary DNA; direct-acting antiviral agent; hepatitis C virus; polymerase chain reaction; IC