Psychological treatments of subthreshold depression: a meta-analytic review

Objective:  Subthreshold depression has a considerable impact on the quality of life and carries a high risk of developing major depressive disorder. Psychological treatments for subthreshold depression may be able to reduce depressive symptomatology and prevent the onset of major depression. Method...

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Published inActa Psychiatrica Scandinavica Vol. 115; no. 6; pp. 434 - 441
Main Authors Cuijpers, P., Smit, F., Van Straten, A.
Format Journal Article
LanguageEnglish
Published Oxford, UK Blackwell Publishing Ltd 01.06.2007
Blackwell
Subjects
Online AccessGet full text
ISSN0001-690X
1600-0447
0065-1591
DOI10.1111/j.1600-0447.2007.00998.x

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Abstract Objective:  Subthreshold depression has a considerable impact on the quality of life and carries a high risk of developing major depressive disorder. Psychological treatments for subthreshold depression may be able to reduce depressive symptomatology and prevent the onset of major depression. Method:  We conducted a meta‐analysis of randomized controlled studies examining the effects of psychological treatments for subthreshold depression. We examined the effects on depressive symptoms and the preventive effects on the incidence of major depression. Results:  Seven high‐quality studies with a total of 700 subjects were included. The mean effect size at post‐test was 0.42 (95% CI: 0.23–0.60), with very low heterogeneity. The relative risk of developing a major depressive disorder in subjects who received the intervention was 0.70 (95% CI: 0.47–1.03; P = 0.07). Conclusion:  Psychological treatments have significant effects on subthreshold depression. Furthermore, these interventions may prevent the onset of major depression.
AbstractList Subthreshold depression has a considerable impact on the quality of life and carries a high risk of developing major depressive disorder. Psychological treatments for subthreshold depression may be able to reduce depressive symptomatology and prevent the onset of major depression.OBJECTIVESubthreshold depression has a considerable impact on the quality of life and carries a high risk of developing major depressive disorder. Psychological treatments for subthreshold depression may be able to reduce depressive symptomatology and prevent the onset of major depression.We conducted a meta-analysis of randomized controlled studies examining the effects of psychological treatments for subthreshold depression. We examined the effects on depressive symptoms and the preventive effects on the incidence of major depression.METHODWe conducted a meta-analysis of randomized controlled studies examining the effects of psychological treatments for subthreshold depression. We examined the effects on depressive symptoms and the preventive effects on the incidence of major depression.Seven high-quality studies with a total of 700 subjects were included. The mean effect size at post-test was 0.42 (95% CI: 0.23-0.60), with very low heterogeneity. The relative risk of developing a major depressive disorder in subjects who received the intervention was 0.70 (95% CI: 0.47-1.03; P = 0.07).RESULTSSeven high-quality studies with a total of 700 subjects were included. The mean effect size at post-test was 0.42 (95% CI: 0.23-0.60), with very low heterogeneity. The relative risk of developing a major depressive disorder in subjects who received the intervention was 0.70 (95% CI: 0.47-1.03; P = 0.07).Psychological treatments have significant effects on subthreshold depression. Furthermore, these interventions may prevent the onset of major depression.CONCLUSIONPsychological treatments have significant effects on subthreshold depression. Furthermore, these interventions may prevent the onset of major depression.
Objective:  Subthreshold depression has a considerable impact on the quality of life and carries a high risk of developing major depressive disorder. Psychological treatments for subthreshold depression may be able to reduce depressive symptomatology and prevent the onset of major depression. Method:  We conducted a meta‐analysis of randomized controlled studies examining the effects of psychological treatments for subthreshold depression. We examined the effects on depressive symptoms and the preventive effects on the incidence of major depression. Results:  Seven high‐quality studies with a total of 700 subjects were included. The mean effect size at post‐test was 0.42 (95% CI: 0.23–0.60), with very low heterogeneity. The relative risk of developing a major depressive disorder in subjects who received the intervention was 0.70 (95% CI: 0.47–1.03; P = 0.07). Conclusion:  Psychological treatments have significant effects on subthreshold depression. Furthermore, these interventions may prevent the onset of major depression.
Subthreshold depression has a considerable impact on the quality of life and carries a high risk of developing major depressive disorder. Psychological treatments for subthreshold depression may be able to reduce depressive symptomatology and prevent the onset of major depression. We conducted a meta-analysis of randomized controlled studies examining the effects of psychological treatments for subthreshold depression. We examined the effects on depressive symptoms and the preventive effects on the incidence of major depression. Seven high-quality studies with a total of 700 subjects were included. The mean effect size at post-test was 0.42 (95% CI: 0.23-0.60), with very low heterogeneity. The relative risk of developing a major depressive disorder in subjects who received the intervention was 0.70 (95% CI: 0.47-1.03; P = 0.07). Psychological treatments have significant effects on subthreshold depression. Furthermore, these interventions may prevent the onset of major depression.
Objective:  Subthreshold depression has a considerable impact on the quality of life and carries a high risk of developing major depressive disorder. Psychological treatments for subthreshold depression may be able to reduce depressive symptomatology and prevent the onset of major depression. Method:  We conducted a meta‐analysis of randomized controlled studies examining the effects of psychological treatments for subthreshold depression. We examined the effects on depressive symptoms and the preventive effects on the incidence of major depression. Results:  Seven high‐quality studies with a total of 700 subjects were included. The mean effect size at post‐test was 0.42 (95% CI: 0.23–0.60), with very low heterogeneity. The relative risk of developing a major depressive disorder in subjects who received the intervention was 0.70 (95% CI: 0.47–1.03; P  = 0.07). Conclusion:  Psychological treatments have significant effects on subthreshold depression. Furthermore, these interventions may prevent the onset of major depression.
Objective: Subthreshold depression has a considerable impact on the quality of life and carries a high risk of developing major depressive disorder. Psychological treatments for subthreshold depression may be able to reduce depressive symptomatology and prevent the onset of major depression. Method: We conducted a meta-analysis of randomized controlled studies examining the effects of psychological treatments for subthreshold depression. We examined the effects on depressive symptoms and the preventive effects on the incidence of major depression. Results: Seven high-quality studies with a total of 700 subjects were included. The mean effect size at post-test was 0.42 (95% CI: 0.23-0.60), with very low heterogeneity. The relative risk of developing a major depressive disorder in subjects who received the intervention was 0.70 (95% CI: 0.47-1.03; P = 0.07). Conclusion: Psychological treatments have significant effects on subthreshold depression. Furthermore, these interventions may prevent the onset of major depression.
Author Cuijpers, P.
Van Straten, A.
Smit, F.
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  organization: Department of Clinical Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
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Issue 6
Keywords Mood disorder
Prevention
Treatment
Psychotherapy
depressive disorder
primary prevention
Depression
meta- analysis
Review
Public health
Metaanalysis
Language English
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Cuijpers P, Smit F, Oostenbrink J, De Graaf R, Ten Have M, Beekman A. Economic costs of minor depression: a population-based study. Acta Psychiatr Scand 2007;115:229-236.
Cuijpers P, Dekker J. Psychologische behandeling van depressie: een systematisch overzicht van meta-analyses Nederlands. Tijdschrift voor Geneeskunde 2005;149:1892-1897. [Psychological treatment of depression: A systematic review of meta-analysis. Paper in Dutch, published in the Dutch Journal of Medicine].
Beck DA, Koenig HG. Minor depression: a review of the literature. Int J Psychiatry Med 1996;26:177-209.
Preisig M, Merikangas KR, Angst J. Clinical significance and comorbidity of subthreshold depression and anxiety in the community. Acta Psychiatr Scand 2001;104:96-103.
Rapaport MH, Judd LL. Minor depressive disorder and subsyndromal depressive symptoms: functional impairment and response to treatment. J Affect Disord 1998;48:227-232.
Haringsma R, Engels GI, Cuijpers P, Spinhoven P. Effectiveness of the coping with depression (CWD) course for older adults provided by the community-based mental health care system in the Netherlands: a randomized controlled field trial. Int Psychogeriatr 2006;18:307-325.
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Angst J, Sellaro R, Merikangas KR. Depressive spectrum diagnoses. Compr Psychiatry 2000;41:39-47.
Cuijpers P, Smit F. Excess mortality in depression: a meta-analysis of community studies. J Affect Disord 2002;72:227-236.
Goldberg DP. Plato versus aristotle: categorical and dimensional models for common mental disorders. Compr Psychiatry 2000;41(suppl. 1):8-13.
Judd LL, Rapaport MH, Yonkers KA, Rush AJ, Frank E, Thase ME et al. Randomized, placebo-controlled trial of fluoxetine for acute treatment of minor depressive disorder. Am J Psychiatry 2004;161:1864-1871.
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Cuijpers P, Schoevers RA. Increased mortality in depressive disorders: a review. Curr Psychiatry Rep 2004;6:430-437.
Fergusson DM, Horwood LJ, Ridder EM, Beautrais AL. Subthreshold depression in adolescence and mental health outcomes in adulthood. Arch Gen Psychiatry 2005;62:66-72.
Geiselmann B, Bauer M. Subthreshold depression in the elderly: qualitative or quantitative distinction? Compr Psychiatry 2000;41 (suppl. 1):32-38.
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Clarke GN, Hornbrook M, Lynch F, Polen M, Gale J, Beardslee W et al. A randomized trial of a group cognitive intervention for preventing depression in adolescent offspring of depressed parents. Arch Gen Psychiatry 2001;58:1127-1134.
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Willemse GRWM, Smit F, Cuijpers P, Tiemens BG. Minimal contact psychotherapy for sub-threshold depression in primary care: a randomised trial. Br J Psychiatry 2004;185:416-421.
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References_xml – reference: Beekman AT, Copeland JR, Prince MJ. Review of community prevalence of depression in later life. Br J Psychiatry 1999;174:307-311.
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– reference: Haringsma R, Engels GI, Cuijpers P, Spinhoven P. Effectiveness of the coping with depression (CWD) course for older adults provided by the community-based mental health care system in the Netherlands: a randomized controlled field trial. Int Psychogeriatr 2006;18:307-325.
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– reference: Oxman TE, Sengupta A. Treatment of minor depression. Am J Geriatr Psychiatry 2002;10:256-264.
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– reference: Gotlib IH, Lewinsohn PM, Seeley JR. Symptoms versus a diagnosis of depression: differences in psychosocial functioning. J Consult Clin Psychol 1995;63:90-100.
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– reference: Banazak DA. Minor depression in primary care. J Am Osteopath Assoc 2000;100:783-787.
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– reference: Pincus HA, Davis WW, Mcqueen LE. 'Subthreshold' mental disorders A review and synthesis of studies on minor depression and other 'brand names'. Br J Psychiatry 1999;174:288-296.
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Snippet Objective:  Subthreshold depression has a considerable impact on the quality of life and carries a high risk of developing major depressive disorder....
Objective:  Subthreshold depression has a considerable impact on the quality of life and carries a high risk of developing major depressive disorder....
Subthreshold depression has a considerable impact on the quality of life and carries a high risk of developing major depressive disorder. Psychological...
Objective: Subthreshold depression has a considerable impact on the quality of life and carries a high risk of developing major depressive disorder....
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SubjectTerms Adult and adolescent clinical studies
Biological and medical sciences
Cognitive Therapy - methods
Depression
depressive disorder
Depressive Disorder, Major - diagnosis
Depressive Disorder, Major - psychology
Depressive Disorder, Major - therapy
Humans
Medical sciences
meta-analysis
Mood disorders
primary prevention
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
psychotherapy
Severity of Illness Index
Title Psychological treatments of subthreshold depression: a meta-analytic review
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https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fj.1600-0447.2007.00998.x
https://www.ncbi.nlm.nih.gov/pubmed/17498154
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https://www.proquest.com/docview/70492698
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