PSMA PET/CT guided intensification of therapy in patients at risk of advanced prostate cancer (PATRON): a pragmatic phase III randomized controlled trial - Ménard, Cynthia; Young, Sympascho; Zukotynski, Katherine; Hamilton, Robert J.; Bénard, François; Yip, Steven; McCabe, Christopher; Saad, Fred; Brundage, Michael; Nitulescu, Roy; Bauman, Glenn (BMC cancer, 2022)
Keywords: Adult; Antigens, Neoplasm - metabolism; Biomedical and Life Sciences; Biomedicine; Canada; Cancer Research; Care and treatment; Clinical Trials, Phase III as Topic; Cost benefit analysis; Cost-effectiveness analysis; Diagnosis; Equivalence Trials as Topic; Failure free survival; Fluorine Radioisotopes; GPI-Linked Proteins - metabolism; Health Promotion and Disease Prevention; Humans; Immune system; Intention to Treat Analysis; Male; Medicine/Public Health; Methods; Neoplasm Proteins - metabolism; Neoplasm Recurrence, Local - diagnostic imaging; Neoplasm Recurrence, Local - metabolism; Neoplasm Recurrence, Local - therapy; Neoplasm Staging - methods; Oncology; Overall survival; PET imaging; Phase III clinical trial; Positron Emission Tomography Computed Tomography; Pragmatic Clinical Trials as Topic; Prospective Studies; Prostate cancer; Prostatectomy - methods; Prostatic Neoplasms - diagnostic imaging; Prostatic Neoplasms - metabolism; Prostatic Neoplasms - therapy; PSMA PET; Radiopharmaceuticals; Radiotherapy, Image-Guided - methods; Radiotherapy, Intensity-Modulated - methods; Randomized Controlled Trials as Topic; Risk factors; Study Protocol; Surgery, Computer-Assisted - methods; Surgical Oncology; Testing; Treatment Outcome; Canada; Cost-effectiveness analysis; Failure free survival; Phase III clinical trial; PSMA PET; Overall survival; Radiotherapy; Prostate cancer; Superiority