Algorithm for the management of patients at low, high and very high risk of osteoporotic fractures

Summary Guidance is provided in an international setting on the assessment and specific treatment of postmenopausal women at low, high and very high risk of fragility fractures. Introduction The International Osteoporosis Foundation and European Society for Clinical and Economic Aspects of Osteoporo...

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Published inOsteoporosis international Vol. 31; no. 1; pp. 1 - 12
Main Authors Kanis, J. A., Harvey, N. C., McCloskey, E., Bruyère, O., Veronese, N., Lorentzon, M., Cooper, C., Rizzoli, R., Adib, G., Al-Daghri, N., Campusano, C., Chandran, M., Dawson-Hughes, B., Javaid, K., Jiwa, F., Johansson, H., Lee, J. K., Liu, E., Messina, D., Mkinsi, O., Pinto, D., Prieto-Alhambra, D., Saag, K., Xia, W., Zakraoui, L., Reginster, J. -Y.
Format Journal Article
LanguageEnglish
Published London Springer London 01.01.2020
Springer Nature B.V
Subjects
Aged
Algorithms
Anabolic agents
bmd
Bone Density
Endocrinology
Endocrinology & Metabolism
Endocrinology and Diabetes
Endokrinologi och diabetes
exercise
Female
Fracture risk assessment
Fractures
FRAX
hip fracture
Hormone replacement therapy
Humans
Inhibitors of bone
intervention thresholds
Management
Medicine
Medicine & Public Health
Middle Aged
older-adults
Orthopedics
Osteoarthritis
Osteoporosis
Osteoporosis, Postmenopausal - complications
Osteoporosis, Postmenopausal - drug therapy
Osteoporosis, Postmenopausal - epidemiology
Osteoporotic Fractures - epidemiology
Osteoporotic Fractures - etiology
Osteoporotic Fractures - prevention & control
Position Paper
Post-menopause
postmenopausal women
prevention
resorption
Rheumatology
Risk Assessment
Risk Factors
teriparatide
time
trabecular bone score
Treatment of osteoporosis
Treatment of osteoporosis
FRAX
Anabolic agents
Fracture risk assessment
Inhibitors of bone resorption
Online AccessGet full text
ISSN0937-941X
1433-2965
1433-2965
DOI10.1007/s00198-019-05176-3

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Abstract Summary Guidance is provided in an international setting on the assessment and specific treatment of postmenopausal women at low, high and very high risk of fragility fractures. Introduction The International Osteoporosis Foundation and European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis published guidance for the diagnosis and management of osteoporosis in 2019. This manuscript seeks to apply this in an international setting, taking additional account of further categorisation of increased risk of fracture, which may inform choice of therapeutic approach. Methods Clinical perspective and updated literature search. Results The following areas are reviewed: categorisation of fracture risk and general pharmacological management of osteoporosis. Conclusions A platform is provided on which specific guidelines can be developed for national use to characterise fracture risk and direct interventions.
AbstractList Summary Guidance is provided in an international setting on the assessment and specific treatment of postmenopausal women at low, high and very high risk of fragility fractures. Introduction The International Osteoporosis Foundation and European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis published guidance for the diagnosis and management of osteoporosis in 2019. This manuscript seeks to apply this in an international setting, taking additional account of further categorisation of increased risk of fracture, which may inform choice of therapeutic approach. Methods Clinical perspective and updated literature search. Results The following areas are reviewed: categorisation of fracture risk and general pharmacological management of osteoporosis. Conclusions A platform is provided on which specific guidelines can be developed for national use to characterise fracture risk and direct interventions.
Guidance is provided in an international setting on the assessment and specific treatment of postmenopausal women at low, high and very high risk of fragility fractures. Introduction The International Osteoporosis Foundation and European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis published guidance for the diagnosis and management of osteoporosis in 2019. This manuscript seeks to apply this in an international setting, taking additional account of further categorisation of increased risk of fracture, which may inform choice of therapeutic approach. Methods Clinical perspective and updated literature search. Results The following areas are reviewed: categorisation of fracture risk and general pharmacological management of osteoporosis. Conclusions A platform is provided on which specific guidelines can be developed for national use to characterise fracture risk and direct interventions.
Guidance is provided in an international setting on the assessment and specific treatment of postmenopausal women at low, high and very high risk of fragility fractures.Guidance is provided in an international setting on the assessment and specific treatment of postmenopausal women at low, high and very high risk of fragility fractures.The International Osteoporosis Foundation and European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis published guidance for the diagnosis and management of osteoporosis in 2019. This manuscript seeks to apply this in an international setting, taking additional account of further categorisation of increased risk of fracture, which may inform choice of therapeutic approach.INTRODUCTIONThe International Osteoporosis Foundation and European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis published guidance for the diagnosis and management of osteoporosis in 2019. This manuscript seeks to apply this in an international setting, taking additional account of further categorisation of increased risk of fracture, which may inform choice of therapeutic approach.Clinical perspective and updated literature search.METHODSClinical perspective and updated literature search.The following areas are reviewed: categorisation of fracture risk and general pharmacological management of osteoporosis.RESULTSThe following areas are reviewed: categorisation of fracture risk and general pharmacological management of osteoporosis.A platform is provided on which specific guidelines can be developed for national use to characterise fracture risk and direct interventions.CONCLUSIONSA platform is provided on which specific guidelines can be developed for national use to characterise fracture risk and direct interventions.
SummaryGuidance is provided in an international setting on the assessment and specific treatment of postmenopausal women at low, high and very high risk of fragility fractures.IntroductionThe International Osteoporosis Foundation and European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis published guidance for the diagnosis and management of osteoporosis in 2019. This manuscript seeks to apply this in an international setting, taking additional account of further categorisation of increased risk of fracture, which may inform choice of therapeutic approach.MethodsClinical perspective and updated literature search.ResultsThe following areas are reviewed: categorisation of fracture risk and general pharmacological management of osteoporosis.ConclusionsA platform is provided on which specific guidelines can be developed for national use to characterise fracture risk and direct interventions.
Guidance is provided in an international setting on the assessment and specific treatment of postmenopausal women at low, high and very high risk of fragility fractures. The International Osteoporosis Foundation and European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis published guidance for the diagnosis and management of osteoporosis in 2019. This manuscript seeks to apply this in an international setting, taking additional account of further categorisation of increased risk of fracture, which may inform choice of therapeutic approach. Clinical perspective and updated literature search. The following areas are reviewed: categorisation of fracture risk and general pharmacological management of osteoporosis. A platform is provided on which specific guidelines can be developed for national use to characterise fracture risk and direct interventions.
Author Lorentzon, M.
Pinto, D.
Johansson, H.
Jiwa, F.
Bruyère, O.
Rizzoli, R.
McCloskey, E.
Saag, K.
Al-Daghri, N.
Messina, D.
Adib, G.
Dawson-Hughes, B.
Chandran, M.
Javaid, K.
Lee, J. K.
Prieto-Alhambra, D.
Xia, W.
Veronese, N.
Cooper, C.
Campusano, C.
Harvey, N. C.
Zakraoui, L.
Kanis, J. A.
Reginster, J. -Y.
Liu, E.
Mkinsi, O.
Author_xml – sequence: 1
  givenname: J. A.
  orcidid: 0000-0002-3129-4326
  surname: Kanis
  fullname: Kanis, J. A.
  email: w.j.Pontefract@shef.ac.uk
  organization: Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Mary McKillop Health Institute, Australian Catholic University
– sequence: 2
  givenname: N. C.
  surname: Harvey
  fullname: Harvey, N. C.
  organization: MRC Lifecourse Epidemiology Unit, University of Southampton
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  surname: McCloskey
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  organization: Centre for Metabolic Bone Diseases, University of Sheffield Medical School, MRC and Arthritis Research UK Centre for Integrated Research in Musculoskeletal Ageing Mellanby
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  givenname: O.
  surname: Bruyère
  fullname: Bruyère, O.
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  givenname: N.
  surname: Veronese
  fullname: Veronese, N.
  organization: National Research Council, Neuroscience Institute, Aging Branch
– sequence: 6
  givenname: M.
  surname: Lorentzon
  fullname: Lorentzon, M.
  organization: Mary McKillop Health Institute, Australian Catholic University, Geriatric Medicine, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, Region Västra Götaland, Geriatric Medicine Clinic, Sahlgrenska University Hospital
– sequence: 7
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  surname: Cooper
  fullname: Cooper, C.
  organization: MRC Lifecourse Epidemiology Unit, University of Southampton, NIHR Musculoskeletal Biomedical Research Unit, University of Oxford
– sequence: 8
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  surname: Rizzoli
  fullname: Rizzoli, R.
  organization: Service of Bone Diseases, Geneva University Hospitals and Faculty of Medicine
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  surname: Adib
  fullname: Adib, G.
  organization: Syrian National Osteoporosis Society
– sequence: 10
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  surname: Al-Daghri
  fullname: Al-Daghri, N.
  organization: Chair for Biomarkers of Chronic Diseases, Biochemistry Dept., College of Science, King Saud University
– sequence: 11
  givenname: C.
  surname: Campusano
  fullname: Campusano, C.
  organization: Clinica Universidad de los Andes and Faculty of Medicine, Universidad de los Andes
– sequence: 12
  givenname: M.
  surname: Chandran
  fullname: Chandran, M.
  organization: Osteoporosis and Bone Metabolism Unit, Department of Endocrinology, Singapore General Hospital, ACADEMIA
– sequence: 13
  givenname: B.
  surname: Dawson-Hughes
  fullname: Dawson-Hughes, B.
  organization: Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University
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  givenname: K.
  surname: Javaid
  fullname: Javaid, K.
  organization: NIHR Musculoskeletal Biomedical Research Unit, University of Oxford
– sequence: 15
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  surname: Jiwa
  fullname: Jiwa, F.
  organization: Chair of the Committee of Patients Societies at the International Osteoporosis Foundation, Osteoporosis Canada
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  givenname: H.
  surname: Johansson
  fullname: Johansson, H.
  organization: Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Mary McKillop Health Institute, Australian Catholic University
– sequence: 17
  givenname: J. K.
  surname: Lee
  fullname: Lee, J. K.
  organization: Beacon International Specialist Centre
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  givenname: E.
  surname: Liu
  fullname: Liu, E.
  organization: Mary McKillop Health Institute, Australian Catholic University
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  surname: Messina
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  organization: IRO Medical Research Center, Buenos Aires and Rheumatology section, Cosme Argerich
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  surname: Mkinsi
  fullname: Mkinsi, O.
  organization: Department of Rheumatology, Ibn Rochd University Hospital
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  surname: Reginster
  fullname: Reginster, J. -Y.
  organization: Chair for Biomarkers of Chronic Diseases, Biochemistry Dept., College of Science, King Saud University, Department of Public Health, Epidemiology and Health Economics, University of Liège
BackLink https://www.ncbi.nlm.nih.gov/pubmed/31720707$$D View this record in MEDLINE/PubMed
https://gup.ub.gu.se/publication/286387$$DView record from Swedish Publication Index
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Issue 1
Keywords Treatment of osteoporosis
FRAX
Anabolic agents
Fracture risk assessment
Inhibitors of bone resorption
Language English
License Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.
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PublicationSubtitle With other metabolic bone diseases
PublicationTitle Osteoporosis international
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31953592 - Osteoporos Int. 2020 May;31(5):1015. doi: 10.1007/s00198-020-05302-6.
32065251 - Osteoporos Int. 2020 Apr;31(4):797-798. doi: 10.1007/s00198-020-05297-0.
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Snippet Summary Guidance is provided in an international setting on the assessment and specific treatment of postmenopausal women at low, high and very high risk of...
Guidance is provided in an international setting on the assessment and specific treatment of postmenopausal women at low, high and very high risk of fragility...
SummaryGuidance is provided in an international setting on the assessment and specific treatment of postmenopausal women at low, high and very high risk of...
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SubjectTerms Aged
Algorithms
Anabolic agents
bmd
Bone Density
Endocrinology
Endocrinology & Metabolism
Endocrinology and Diabetes
Endokrinologi och diabetes
exercise
Female
Fracture risk assessment
Fractures
FRAX
hip fracture
Hormone replacement therapy
Humans
Inhibitors of bone
intervention thresholds
Management
Medicine
Medicine & Public Health
Middle Aged
older-adults
Orthopedics
Osteoarthritis
Osteoporosis
Osteoporosis, Postmenopausal - complications
Osteoporosis, Postmenopausal - drug therapy
Osteoporosis, Postmenopausal - epidemiology
Osteoporotic Fractures - epidemiology
Osteoporotic Fractures - etiology
Osteoporotic Fractures - prevention & control
Position Paper
Post-menopause
postmenopausal women
prevention
resorption
Rheumatology
Risk Assessment
Risk Factors
teriparatide
time
trabecular bone score
Treatment of osteoporosis
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Title Algorithm for the management of patients at low, high and very high risk of osteoporotic fractures
URI https://link.springer.com/article/10.1007/s00198-019-05176-3
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Volume 31
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