Vitreous metabolomics profiling of proliferative diabetic retinopathy - Tomita, Yohei; Cagnone, Gael; Fu, Zhongjie; Cakir, Bertan; Kotoda, Yumi; Asakage, Masaki; Wakabayashi, Yoshihiro; Hellström, Ann; Joyal, Jean-Sébastien; Talukdar, Saswata; Smith, Lois E. H.; Usui, Yoshihiko (Diabetologia, 2021)
Keywords: Adult; Aged; Aged, 80 and over; Allantoin; Amino Acids - analysis; angiogenesis; Animals; anti-vegf; Chromatography, High Pressure Liquid; Creatine; Creatine - administration & dosage; Creatine - analysis; Diabetes; Diabetes mellitus; Diabetic retinopathy; Diabetic Retinopathy - metabolism; Diabetic Retinopathy - physiopathology; Dietary supplements; Endocrinology & Metabolism; Endocrinology and Diabetes; Endokrinologi och diabetes; Female; High-performance liquid chromatography; Human Physiology; Humans; Internal Medicine; Lactic acid; Male; Mass Spectrometry; Mass spectroscopy; Medicine; Medicine & Public Health; Metabolic Diseases; Metabolites; Metabolomics; Mice; Mice, Inbred C57BL; Middle Aged; mouse; Oftalmologi; Ophthalmology; Oxygen-induced retinopathy; pdgf-cc; Proliferative; Proline; Pyruvic acid; quantification; Retina; Retinal neovascularisation; Retinal Neovascularization - metabolism; Retinopathy; reveals; Vitreous Body - chemistry; Vitreous Body - metabolism; Metabolomics; Creatine; Proliferative diabetic retinopathy; Oxygen-induced retinopathy; Retinal neovascularisation