Obstetric admission and maternal mortality in the intensive care unit in Africa: A systematic review and meta-analysis
Obstetric complications are a major contributor to maternal morbidity and mortality worldwide, especially in low-resource settings such as many countries in Africa. Intensive care units offer specialized care for women with severe obstetric complications, which require advanced monitoring and therap...
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| Published in | PloS one Vol. 20; no. 4; p. e0320254 |
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| Main Authors | , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Public Library of Science
16.04.2025
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1932-6203 1932-6203 |
| DOI | 10.1371/journal.pone.0320254 |
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| Abstract | Obstetric complications are a major contributor to maternal morbidity and mortality worldwide, especially in low-resource settings such as many countries in Africa. Intensive care units offer specialized care for women with severe obstetric complications, which require advanced monitoring and therapeutic interventions. Despite the critical importance of ICU care, there is a paucity of comprehensive data on obstetric ICU admissions and outcomes in Africa. Therefore, this study aimed to assess the proportion of obstetric admissions and maternal mortality in the intensive care unit in Africa.
To assess the proportion of obstetric admissions and maternal mortality in the intensive care unit in Africa.
The Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA 2020) guidelines were followed in reporting the study's findings. Articles searched; from PubMed, HINARI, Web of Science, Google Scholar, Repository, and African Journals Online were systematically searched for reports of obstetric admission in the intensive care unit, either pregnant or up to 6 weeks postpartum. The Joanna Briggs Institute (JBI) Critical Appraisal tool was used to evaluate each article's quality. The Stata 17 software was used to compute the analysis. The heterogeneity of the studies was detected using the Cochran Q test and I2 test statistics, which were considered significant at p < 0.05. The random effect model of analysis was used with evidence of heterogeneity. Egger's test at p < 0.05 was used to check the evidence of publication bias within the studies. Subgroup analysis and sensitivity analysis were done.
Eleven studies were included in this study with a total of 10,190 mothers admitted to the intensive care unit. The overall pooled proportion of obstetric intensive care unit admissions in Africa was 17.22% (95% CI; 12.97-21.47; I2 = 97.63%). This translates to roughly 17 out of every 100 ICU admissions being for obstetric complications. Hypertensive disorders of pregnancy 42.96% (95% CI: 27.3, 58.56) and obstetric hemorrhage 24.15% (95% CI: 18.12, 30.18) were the common indications for obstetric admission in the intensive care unit.. Maternal mortality among ICU-admitted patients reached a concerning 30.69% (95% CI: 23.16, 38.22; I2= 93.34%). This means that, nearly one in three women admitted to the ICU for obstetric complications died.
In Africa, the proportion of obstetric admissions and maternal mortality in the intensive care unit is significant. This high percentage of obstetric admissions and maternal mortality in the ICU highlights the necessity to enhance emergency obstetric care services and invest in the development of well-equipped obstetric ICUs to reduce maternal mortality.
CRD42024516612. |
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| AbstractList | Obstetric complications are a major contributor to maternal morbidity and mortality worldwide, especially in low-resource settings such as many countries in Africa. Intensive care units offer specialized care for women with severe obstetric complications, which require advanced monitoring and therapeutic interventions. Despite the critical importance of ICU care, there is a paucity of comprehensive data on obstetric ICU admissions and outcomes in Africa. Therefore, this study aimed to assess the proportion of obstetric admissions and maternal mortality in the intensive care unit in Africa. To assess the proportion of obstetric admissions and maternal mortality in the intensive care unit in Africa. The Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA 2020) guidelines were followed in reporting the study's findings. Articles searched; from PubMed, HINARI, Web of Science, Google Scholar, Repository, and African Journals Online were systematically searched for reports of obstetric admission in the intensive care unit, either pregnant or up to 6 weeks postpartum. The Joanna Briggs Institute (JBI) Critical Appraisal tool was used to evaluate each article's quality. The Stata 17 software was used to compute the analysis. The heterogeneity of the studies was detected using the Cochran Q test and I.sup.2 test statistics, which were considered significant at p < 0.05. The random effect model of analysis was used with evidence of heterogeneity. Egger's test at p < 0.05 was used to check the evidence of publication bias within the studies. Subgroup analysis and sensitivity analysis were done. Eleven studies were included in this study with a total of 10,190 mothers admitted to the intensive care unit. The overall pooled proportion of obstetric intensive care unit admissions in Africa was 17.22% (95% CI; 12.97-21.47; I.sup.2 = 97.63%). This translates to roughly 17 out of every 100 ICU admissions being for obstetric complications. Hypertensive disorders of pregnancy 42.96% (95% CI: 27.3, 58.56) and obstetric hemorrhage 24.15% (95% CI: 18.12, 30.18) were the common indications for obstetric admission in the intensive care unit.. Maternal mortality among ICU-admitted patients reached a concerning 30.69% (95% CI: 23.16, 38.22; I.sup.2 = 93.34%). This means that, nearly one in three women admitted to the ICU for obstetric complications died. In Africa, the proportion of obstetric admissions and maternal mortality in the intensive care unit is significant. This high percentage of obstetric admissions and maternal mortality in the ICU highlights the necessity to enhance emergency obstetric care services and invest in the development of well-equipped obstetric ICUs to reduce maternal mortality. Background Obstetric complications are a major contributor to maternal morbidity and mortality worldwide, especially in low-resource settings such as many countries in Africa. Intensive care units offer specialized care for women with severe obstetric complications, which require advanced monitoring and therapeutic interventions. Despite the critical importance of ICU care, there is a paucity of comprehensive data on obstetric ICU admissions and outcomes in Africa. Therefore, this study aimed to assess the proportion of obstetric admissions and maternal mortality in the intensive care unit in Africa. Objective To assess the proportion of obstetric admissions and maternal mortality in the intensive care unit in Africa. Methodology The Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA 2020) guidelines were followed in reporting the study's findings. Articles searched; from PubMed, HINARI, Web of Science, Google Scholar, Repository, and African Journals Online were systematically searched for reports of obstetric admission in the intensive care unit, either pregnant or up to 6 weeks postpartum. The Joanna Briggs Institute (JBI) Critical Appraisal tool was used to evaluate each article's quality. The Stata 17 software was used to compute the analysis. The heterogeneity of the studies was detected using the Cochran Q test and I.sup.2 test statistics, which were considered significant at p < 0.05. The random effect model of analysis was used with evidence of heterogeneity. Egger's test at p < 0.05 was used to check the evidence of publication bias within the studies. Subgroup analysis and sensitivity analysis were done. Result Eleven studies were included in this study with a total of 10,190 mothers admitted to the intensive care unit. The overall pooled proportion of obstetric intensive care unit admissions in Africa was 17.22% (95% CI; 12.97-21.47; I.sup.2 = 97.63%). This translates to roughly 17 out of every 100 ICU admissions being for obstetric complications. Hypertensive disorders of pregnancy 42.96% (95% CI: 27.3, 58.56) and obstetric hemorrhage 24.15% (95% CI: 18.12, 30.18) were the common indications for obstetric admission in the intensive care unit.. Maternal mortality among ICU-admitted patients reached a concerning 30.69% (95% CI: 23.16, 38.22; I.sup.2 = 93.34%). This means that, nearly one in three women admitted to the ICU for obstetric complications died. Conclusion In Africa, the proportion of obstetric admissions and maternal mortality in the intensive care unit is significant. This high percentage of obstetric admissions and maternal mortality in the ICU highlights the necessity to enhance emergency obstetric care services and invest in the development of well-equipped obstetric ICUs to reduce maternal mortality. Registration CRD42024516612. Background Obstetric complications are a major contributor to maternal morbidity and mortality worldwide, especially in low-resource settings such as many countries in Africa. Intensive care units offer specialized care for women with severe obstetric complications, which require advanced monitoring and therapeutic interventions. Despite the critical importance of ICU care, there is a paucity of comprehensive data on obstetric ICU admissions and outcomes in Africa. Therefore, this study aimed to assess the proportion of obstetric admissions and maternal mortality in the intensive care unit in Africa. Objective To assess the proportion of obstetric admissions and maternal mortality in the intensive care unit in Africa. Methodology The Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA 2020) guidelines were followed in reporting the study’s findings. Articles searched; from PubMed, HINARI, Web of Science, Google Scholar, Repository, and African Journals Online were systematically searched for reports of obstetric admission in the intensive care unit, either pregnant or up to 6 weeks postpartum. The Joanna Briggs Institute (JBI) Critical Appraisal tool was used to evaluate each article’s quality. The Stata 17 software was used to compute the analysis. The heterogeneity of the studies was detected using the Cochran Q test and I 2 test statistics, which were considered significant at p < 0.05. The random effect model of analysis was used with evidence of heterogeneity. Egger’s test at p < 0.05 was used to check the evidence of publication bias within the studies. Subgroup analysis and sensitivity analysis were done. Result Eleven studies were included in this study with a total of 10,190 mothers admitted to the intensive care unit. The overall pooled proportion of obstetric intensive care unit admissions in Africa was 17.22% (95% CI; 12.97–21.47; I 2 = 97.63%). This translates to roughly 17 out of every 100 ICU admissions being for obstetric complications. Hypertensive disorders of pregnancy 42.96% (95% CI: 27.3, 58.56) and obstetric hemorrhage 24.15% (95% CI: 18.12, 30.18) were the common indications for obstetric admission in the intensive care unit.. Maternal mortality among ICU-admitted patients reached a concerning 30.69% (95% CI: 23.16, 38.22; I 2 = 93.34%). This means that, nearly one in three women admitted to the ICU for obstetric complications died. Conclusion In Africa, the proportion of obstetric admissions and maternal mortality in the intensive care unit is significant. This high percentage of obstetric admissions and maternal mortality in the ICU highlights the necessity to enhance emergency obstetric care services and invest in the development of well-equipped obstetric ICUs to reduce maternal mortality. Registration CRD42024516612. BackgroundObstetric complications are a major contributor to maternal morbidity and mortality worldwide, especially in low-resource settings such as many countries in Africa. Intensive care units offer specialized care for women with severe obstetric complications, which require advanced monitoring and therapeutic interventions. Despite the critical importance of ICU care, there is a paucity of comprehensive data on obstetric ICU admissions and outcomes in Africa. Therefore, this study aimed to assess the proportion of obstetric admissions and maternal mortality in the intensive care unit in Africa.ObjectiveTo assess the proportion of obstetric admissions and maternal mortality in the intensive care unit in Africa.MethodologyThe Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA 2020) guidelines were followed in reporting the study’s findings. Articles searched; from PubMed, HINARI, Web of Science, Google Scholar, Repository, and African Journals Online were systematically searched for reports of obstetric admission in the intensive care unit, either pregnant or up to 6 weeks postpartum. The Joanna Briggs Institute (JBI) Critical Appraisal tool was used to evaluate each article’s quality. The Stata 17 software was used to compute the analysis. The heterogeneity of the studies was detected using the Cochran Q test and I2 test statistics, which were considered significant at p < 0.05. The random effect model of analysis was used with evidence of heterogeneity. Egger’s test at p < 0.05 was used to check the evidence of publication bias within the studies. Subgroup analysis and sensitivity analysis were done.ResultEleven studies were included in this study with a total of 10,190 mothers admitted to the intensive care unit. The overall pooled proportion of obstetric intensive care unit admissions in Africa was 17.22% (95% CI; 12.97–21.47; I2 = 97.63%). This translates to roughly 17 out of every 100 ICU admissions being for obstetric complications. Hypertensive disorders of pregnancy 42.96% (95% CI: 27.3, 58.56) and obstetric hemorrhage 24.15% (95% CI: 18.12, 30.18) were the common indications for obstetric admission in the intensive care unit.. Maternal mortality among ICU-admitted patients reached a concerning 30.69% (95% CI: 23.16, 38.22; I2= 93.34%). This means that, nearly one in three women admitted to the ICU for obstetric complications died.ConclusionIn Africa, the proportion of obstetric admissions and maternal mortality in the intensive care unit is significant. This high percentage of obstetric admissions and maternal mortality in the ICU highlights the necessity to enhance emergency obstetric care services and invest in the development of well-equipped obstetric ICUs to reduce maternal mortality.RegistrationCRD42024516612. Obstetric complications are a major contributor to maternal morbidity and mortality worldwide, especially in low-resource settings such as many countries in Africa. Intensive care units offer specialized care for women with severe obstetric complications, which require advanced monitoring and therapeutic interventions. Despite the critical importance of ICU care, there is a paucity of comprehensive data on obstetric ICU admissions and outcomes in Africa. Therefore, this study aimed to assess the proportion of obstetric admissions and maternal mortality in the intensive care unit in Africa. To assess the proportion of obstetric admissions and maternal mortality in the intensive care unit in Africa. The Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA 2020) guidelines were followed in reporting the study's findings. Articles searched; from PubMed, HINARI, Web of Science, Google Scholar, Repository, and African Journals Online were systematically searched for reports of obstetric admission in the intensive care unit, either pregnant or up to 6 weeks postpartum. The Joanna Briggs Institute (JBI) Critical Appraisal tool was used to evaluate each article's quality. The Stata 17 software was used to compute the analysis. The heterogeneity of the studies was detected using the Cochran Q test and I2 test statistics, which were considered significant at p < 0.05. The random effect model of analysis was used with evidence of heterogeneity. Egger's test at p < 0.05 was used to check the evidence of publication bias within the studies. Subgroup analysis and sensitivity analysis were done. Eleven studies were included in this study with a total of 10,190 mothers admitted to the intensive care unit. The overall pooled proportion of obstetric intensive care unit admissions in Africa was 17.22% (95% CI; 12.97-21.47; I2 = 97.63%). This translates to roughly 17 out of every 100 ICU admissions being for obstetric complications. Hypertensive disorders of pregnancy 42.96% (95% CI: 27.3, 58.56) and obstetric hemorrhage 24.15% (95% CI: 18.12, 30.18) were the common indications for obstetric admission in the intensive care unit.. Maternal mortality among ICU-admitted patients reached a concerning 30.69% (95% CI: 23.16, 38.22; I2= 93.34%). This means that, nearly one in three women admitted to the ICU for obstetric complications died. In Africa, the proportion of obstetric admissions and maternal mortality in the intensive care unit is significant. This high percentage of obstetric admissions and maternal mortality in the ICU highlights the necessity to enhance emergency obstetric care services and invest in the development of well-equipped obstetric ICUs to reduce maternal mortality. CRD42024516612. Obstetric complications are a major contributor to maternal morbidity and mortality worldwide, especially in low-resource settings such as many countries in Africa. Intensive care units offer specialized care for women with severe obstetric complications, which require advanced monitoring and therapeutic interventions. Despite the critical importance of ICU care, there is a paucity of comprehensive data on obstetric ICU admissions and outcomes in Africa. Therefore, this study aimed to assess the proportion of obstetric admissions and maternal mortality in the intensive care unit in Africa.BACKGROUNDObstetric complications are a major contributor to maternal morbidity and mortality worldwide, especially in low-resource settings such as many countries in Africa. Intensive care units offer specialized care for women with severe obstetric complications, which require advanced monitoring and therapeutic interventions. Despite the critical importance of ICU care, there is a paucity of comprehensive data on obstetric ICU admissions and outcomes in Africa. Therefore, this study aimed to assess the proportion of obstetric admissions and maternal mortality in the intensive care unit in Africa.To assess the proportion of obstetric admissions and maternal mortality in the intensive care unit in Africa.OBJECTIVETo assess the proportion of obstetric admissions and maternal mortality in the intensive care unit in Africa.The Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA 2020) guidelines were followed in reporting the study's findings. Articles searched; from PubMed, HINARI, Web of Science, Google Scholar, Repository, and African Journals Online were systematically searched for reports of obstetric admission in the intensive care unit, either pregnant or up to 6 weeks postpartum. The Joanna Briggs Institute (JBI) Critical Appraisal tool was used to evaluate each article's quality. The Stata 17 software was used to compute the analysis. The heterogeneity of the studies was detected using the Cochran Q test and I2 test statistics, which were considered significant at p < 0.05. The random effect model of analysis was used with evidence of heterogeneity. Egger's test at p < 0.05 was used to check the evidence of publication bias within the studies. Subgroup analysis and sensitivity analysis were done.METHODOLOGYThe Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA 2020) guidelines were followed in reporting the study's findings. Articles searched; from PubMed, HINARI, Web of Science, Google Scholar, Repository, and African Journals Online were systematically searched for reports of obstetric admission in the intensive care unit, either pregnant or up to 6 weeks postpartum. The Joanna Briggs Institute (JBI) Critical Appraisal tool was used to evaluate each article's quality. The Stata 17 software was used to compute the analysis. The heterogeneity of the studies was detected using the Cochran Q test and I2 test statistics, which were considered significant at p < 0.05. The random effect model of analysis was used with evidence of heterogeneity. Egger's test at p < 0.05 was used to check the evidence of publication bias within the studies. Subgroup analysis and sensitivity analysis were done.Eleven studies were included in this study with a total of 10,190 mothers admitted to the intensive care unit. The overall pooled proportion of obstetric intensive care unit admissions in Africa was 17.22% (95% CI; 12.97-21.47; I2 = 97.63%). This translates to roughly 17 out of every 100 ICU admissions being for obstetric complications. Hypertensive disorders of pregnancy 42.96% (95% CI: 27.3, 58.56) and obstetric hemorrhage 24.15% (95% CI: 18.12, 30.18) were the common indications for obstetric admission in the intensive care unit.. Maternal mortality among ICU-admitted patients reached a concerning 30.69% (95% CI: 23.16, 38.22; I2= 93.34%). This means that, nearly one in three women admitted to the ICU for obstetric complications died.RESULTEleven studies were included in this study with a total of 10,190 mothers admitted to the intensive care unit. The overall pooled proportion of obstetric intensive care unit admissions in Africa was 17.22% (95% CI; 12.97-21.47; I2 = 97.63%). This translates to roughly 17 out of every 100 ICU admissions being for obstetric complications. Hypertensive disorders of pregnancy 42.96% (95% CI: 27.3, 58.56) and obstetric hemorrhage 24.15% (95% CI: 18.12, 30.18) were the common indications for obstetric admission in the intensive care unit.. Maternal mortality among ICU-admitted patients reached a concerning 30.69% (95% CI: 23.16, 38.22; I2= 93.34%). This means that, nearly one in three women admitted to the ICU for obstetric complications died.In Africa, the proportion of obstetric admissions and maternal mortality in the intensive care unit is significant. This high percentage of obstetric admissions and maternal mortality in the ICU highlights the necessity to enhance emergency obstetric care services and invest in the development of well-equipped obstetric ICUs to reduce maternal mortality.CONCLUSIONIn Africa, the proportion of obstetric admissions and maternal mortality in the intensive care unit is significant. This high percentage of obstetric admissions and maternal mortality in the ICU highlights the necessity to enhance emergency obstetric care services and invest in the development of well-equipped obstetric ICUs to reduce maternal mortality.CRD42024516612.REGISTRATIONCRD42024516612. |
| Audience | Academic |
| Author | Getie Mehari, Molla Kassie Worku, Nigus Eseyneh Dagnew, Tenagnework Melese, Mihret Workie Limenh, Liknaw Talie Fenta, Eneyew Mebrat Delie, Amare Hailu, Mickiale Abie, Alemwork Esubalew, Dereje |
| AuthorAffiliation | 2 Department of Medical Laboratory Science, College of Medicine and Health Sciences, Injibara University, Injibara, Ethiopia Debre Tabor University, ETHIOPIA 5 Department of Pharmaceutics, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia 3 Department of Public Health, College of Medicine and Health Sciences, Injibara University, Injibara, Ethiopia 1 Department of Midwifery, College of Medicine and Health Science, Bahir Dar University, Bahir Dar, Ethiopia 8 Department of Midwifery, College of Medicine and Health Science, Dire Dawa University, Dire Dawa, Ethiopia 6 Department of Public Health, College of Medicine and Health Science, Dire Dawa University, Dire Dawa, Ethiopia 4 Department of Human Physiology, School of Medicine, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia 7 Department of Human Physiology, College of Medicine and Health Science, Ambo University, Ambo, Ethiopia |
| AuthorAffiliation_xml | – name: 3 Department of Public Health, College of Medicine and Health Sciences, Injibara University, Injibara, Ethiopia – name: Debre Tabor University, ETHIOPIA – name: 2 Department of Medical Laboratory Science, College of Medicine and Health Sciences, Injibara University, Injibara, Ethiopia – name: 7 Department of Human Physiology, College of Medicine and Health Science, Ambo University, Ambo, Ethiopia – name: 6 Department of Public Health, College of Medicine and Health Science, Dire Dawa University, Dire Dawa, Ethiopia – name: 5 Department of Pharmaceutics, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia – name: 8 Department of Midwifery, College of Medicine and Health Science, Dire Dawa University, Dire Dawa, Ethiopia – name: 1 Department of Midwifery, College of Medicine and Health Science, Bahir Dar University, Bahir Dar, Ethiopia – name: 4 Department of Human Physiology, School of Medicine, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia |
| Author_xml | – sequence: 1 givenname: Alemwork orcidid: 0000-0002-3901-7905 surname: Abie fullname: Abie, Alemwork – sequence: 2 givenname: Molla surname: Getie Mehari fullname: Getie Mehari, Molla – sequence: 3 givenname: Tenagnework surname: Eseyneh Dagnew fullname: Eseyneh Dagnew, Tenagnework – sequence: 4 givenname: Amare surname: Mebrat Delie fullname: Mebrat Delie, Amare – sequence: 5 givenname: Mihret surname: Melese fullname: Melese, Mihret – sequence: 6 givenname: Liknaw orcidid: 0000-0002-9680-6134 surname: Workie Limenh fullname: Workie Limenh, Liknaw – sequence: 7 givenname: Nigus surname: Kassie Worku fullname: Kassie Worku, Nigus – sequence: 8 givenname: Eneyew surname: Talie Fenta fullname: Talie Fenta, Eneyew – sequence: 9 givenname: Dereje surname: Esubalew fullname: Esubalew, Dereje – sequence: 10 givenname: Mickiale surname: Hailu fullname: Hailu, Mickiale |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/40238732$$D View this record in MEDLINE/PubMed |
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| Copyright | Copyright: © 2025 Abie et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. COPYRIGHT 2025 Public Library of Science 2025 Abie et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. 2025 Abie et al 2025 Abie et al 2025 Abie et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| Copyright_xml | – notice: Copyright: © 2025 Abie et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. – notice: COPYRIGHT 2025 Public Library of Science – notice: 2025 Abie et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. – notice: 2025 Abie et al 2025 Abie et al – notice: 2025 Abie et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
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| DOI | 10.1371/journal.pone.0320254 |
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| Snippet | Obstetric complications are a major contributor to maternal morbidity and mortality worldwide, especially in low-resource settings such as many countries in... Background Obstetric complications are a major contributor to maternal morbidity and mortality worldwide, especially in low-resource settings such as many... BackgroundObstetric complications are a major contributor to maternal morbidity and mortality worldwide, especially in low-resource settings such as many... Background Obstetric complications are a major contributor to maternal morbidity and mortality worldwide, especially in low-resource settings such as many... |
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| Title | Obstetric admission and maternal mortality in the intensive care unit in Africa: A systematic review and meta-analysis |
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