Loss of GSTO2 contributes to cell growth and mitochondria function via the p38 signaling in lung squamous cell carcinoma - Sumiya, Ryusuke; Terayama, Masayoshi; Hagiwara, Teruki; Nakata, Kazuaki; Sekihara, Keigo; Nagasaka, Satoshi; Miyazaki, Hideki; Igari, Toru; Yamada, Kazuhiko; Kawamura, Yuki I. (Cancer science, 2022)
Keywords: Acidification; Alveoli; Animals; Basal cells; cancer metabolism; Carcinoma, Squamous Cell - genetics; Carcinoma, Squamous Cell - pathology; Catenin; Cell growth; Cell Line, Tumor; Chronic obstructive pulmonary disease; Decitabine - pharmacology; Deoxyribonucleic acid; DNA; DNA Methylation - drug effects; DNA methyltransferase; Down-Regulation - drug effects; Epigenesis, Genetic; Gene expression; Gene Expression Regulation, Neoplastic - drug effects; Glutathione; Glutathione Transferase - genetics; Glycolysis; GSTO2; Humans; Intravenous administration; Kinases; Laboratories; Liver Neoplasms - genetics; Liver Neoplasms - pathology; Liver Neoplasms - secondary; LSCC; Lung cancer; Lung carcinoma; Lung Neoplasms - genetics; Lung Neoplasms - pathology; Male; MAP Kinase Signaling System - drug effects; Membrane potential; Metabolism; Metastases; Mice; Mice, Nude; Mitochondria; Mutation; Neoplasm Transplantation; Original; Oxidative Phosphorylation; Oxygen consumption; p38; Respiratory function; Signal transduction; Squamous cell carcinoma; Stem cells; Transcription; Xenografts; β‐catenin; cancer metabolism; β-catenin; GSTO2; LSCC; p38