Blockade of STING activation alleviates microglial dysfunction and a broad spectrum of Alzheimer’s disease pathologies - Chung, Sunwoo; Jeong, June-Hyun; Park, Jong-Chan; Han, Jong Won; Lee, Yeajina; Kim, Jong-Il; Mook-Jung, Inhee (Experimental & molecular medicine, 2024)
Keywords: 13/100; 14/19; 45/91; 631/378/1689/1283; 631/378/371; 64/110; 82/51; 82/80; Alzheimer Disease - etiology; Alzheimer Disease - genetics; Alzheimer Disease - metabolism; Alzheimer Disease - pathology; Alzheimer's disease; Amyloid beta-Peptides - metabolism; Animals; Apolipoprotein E; Artificial intelligence; Biomedical and Life Sciences; Biomedicine; Brain; Brain injury; Cytoplasm; Dementia disorders; Disease Models, Animal; Gliosis; Humans; Immune response; Immunological memory; Inflammation; Medical Biochemistry; Membrane Proteins - genetics; Membrane Proteins - metabolism; Memory; Mice; Mice, Transgenic; Microglia; Microglia - metabolism; Microglia - pathology; Mitochondrial DNA; Molecular Medicine; Neurodegeneration; Neurodegenerative diseases; Neuronal-glial interactions; Nucleotidyltransferases - genetics; Nucleotidyltransferases - metabolism; Phosphorylation; Proteins; Risk factors; Signal Transduction; Stem Cells; Synapses; Tau protein; Therapeutic targets; Transcriptomes; β-Amyloid; 생화학