Investigating brain–gut microbiota dynamics and inflammatory processes in an autistic-like rat model using MRI biomarkers during childhood and adolescence - Palanivelu, Lalitha; Chen, You-Yin; Chang, Chih-Ju; Liang, Yao-Wen; Tseng, Hsin-Yi; Li, Ssu-Ju; Chang, Ching-Wen; Lo, Yu-Chun (NeuroImage (Orlando, Fla.), 2024)
Keywords: Acetic acid; Adolescence; Animals; Anisotropy; Autism; Autism spectrum disorder; Autism Spectrum Disorder - diagnostic imaging; Autism Spectrum Disorder - immunology; Autism Spectrum Disorder - metabolism; Autism Spectrum Disorder - microbiology; Behavior; Biomarkers; Biomarkers - metabolism; Brain - diagnostic imaging; Brain - metabolism; Brain research; Brain-Gut Axis - physiology; Childhood; Children; Chromatography; Cortex (cingulate); Cytokines; Developmental stages; Diffusion tensor imaging; Diffusion Tensor Imaging - methods; Disease Models, Animal; Dysbacteriosis; Fatty acids; Feces; Female; Gastrointestinal Microbiome; Gut microbiota; Immune system; Inflammation; Inflammation - diagnostic imaging; Inflammation - metabolism; Interleukin 1; Interleukin 6; Intestinal microflora; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Male; Mass spectrometry; Metabolites; Microbiome dysbiosis; Microbiota; Neostriatum; Neurodevelopmental disorders; Neuroimaging; Neuroinflammation; Pregnancy; Prenatal experience; Prenatal exposure; Rats; Rats, Sprague-Dawley; Scientific imaging; Social behavior; Tumor necrosis factor-α; Valproic acid; Valproic Acid - pharmacology; γ-Interferon; Adolescence; VPA; PND; Neuroinflammation; IL-1β; SCFA; Autism spectrum disorder; IL-6; Diffusion tensor imaging; Microbiome dysbiosis; ASD; IFN-γ; TNF-α; Childhood; DTI