Dietary Sodium Restriction Reverses Vascular Endothelial Dysfunction in Middle-Aged/Older Adults With Moderately Elevated Systolic Blood Pressure - Jablonski, Kristen L.; Racine, Matthew L.; Geolfos, Candace J.; Gates, Phillip E.; Chonchol, Michel; McQueen, Matthew B.; Seals, Douglas R. (Journal of the American College of Cardiology, 2013)
Keywords: Aged; aging; Arterial hypertension. Arterial hypotension; Biological and medical sciences; Biological Availability; Biopterins - analogs & derivatives; Biopterins - pharmacokinetics; Blood and lymphatic vessels; Blood pressure; Blood Pressure - physiology; Brachial Artery - physiology; Cardiology; Cardiology. Vascular system; Cardiovascular; Cholesterol; Cross-Over Studies; diet; Diet, Sodium-Restricted; Dose-Response Relationship, Drug; Endothelium, Vascular - physiopathology; Female; Heart; Humans; hypertension; Hypertension - diet therapy; Hypertension - physiopathology; Male; Medical sciences; Microcirculation - physiology; Middle Aged; Nitric oxide; oxidative stress; Oxidative Stress - physiology; Regional Blood Flow; Rodents; Sodium; Sodium, Dietary - administration & dosage; Sodium, Dietary - urine; Vascular Resistance - physiology; Veins & arteries; United States--US; SBP; NO; nitric oxide; DSR; eNOS; FMDBA; EDD; SOD; FBFACh; BH4; CVD; aging; diet; hypertension; CTRC; oxidative stress; tetrahydrobiopterin; BH 4; dietary sodium restriction; brachial artery flow-mediated dilation; systolic blood pressure; FBF ACh; endothelial nitric oxide synthase; Clinical and Translational Research Center; cardiovascular disease; endothelium-dependent dilation; forearm blood flow to acetylcholine; FMD BA; superoxide dismutase; Human; Hypertension; Middle age; Cardiovascular disease; Dietary restraint; Endothelium; Sodium; Dysfunction; Blood vessel; Endothelial dysfunction; Circulatory system; Cardiology; Elderly