有氧运动对乳腺癌化疗患者癌因性疲乏的影响及相关机制

目的探讨有氧运动对乳腺癌化疗患者癌因性疲乏的影响及相关机制。方法 60例根治术术后欲进行化疗的乳腺癌患者随机分为运动组和对照组,各30例。对照组给予常规护理。运动组除常规护理外,在化疗第1天开始有氧运动干预,直到化疗结束。使用Piper疲乏修订量表（RPFS）对疲乏程度进行评估。分别在化疗前、化疗结束和化疗后4周检测两组患者的血红蛋白（Hb）水平、最大摄氧量（VO2max）和RPFS得分情况。结果两组Hb水平在化疗前、化疗结束和化疗后4周差异均无统计学意义（P〉0.05）;化疗结束和化疗后4周,两组Hb水平均低于化疗前（P〈0.05）。化疗前两组VO2max和RPFS得分差异无统计学意义（P〉...

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Bibliographic Details
Published in天津医药 Vol. 44; no. 4; pp. 401 - 404
Main Author 曹玉瑶 宋祎 陈凤敏 徐锦江
Format Journal Article
LanguageChinese
Published 辽宁医学院研究生院 邮编121000%辽宁医学院附属第一医院 2016
Subjects
Piper疲乏量表
体育和训练
最大摄氧量
有氧运动
氧耗量
疲劳
癌因性疲乏
肿瘤
血红蛋白类
aerobic exercise
体育和训练
最大摄氧量
有氧运动
hemoglobins
cancer-related fa-tigue
癌因性疲乏
Piper疲乏量表
疲劳
fatigue
肿瘤
oxygen consumption
氧耗量
physical education and training
VO2max
血红蛋白类
neoplasms
Piper fatigue scale
Online AccessGet full text
ISSN0253-9896
DOI10.11958/20150195

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Summary:目的探讨有氧运动对乳腺癌化疗患者癌因性疲乏的影响及相关机制。方法 60例根治术术后欲进行化疗的乳腺癌患者随机分为运动组和对照组,各30例。对照组给予常规护理。运动组除常规护理外,在化疗第1天开始有氧运动干预,直到化疗结束。使用Piper疲乏修订量表（RPFS）对疲乏程度进行评估。分别在化疗前、化疗结束和化疗后4周检测两组患者的血红蛋白（Hb）水平、最大摄氧量（VO2max）和RPFS得分情况。结果两组Hb水平在化疗前、化疗结束和化疗后4周差异均无统计学意义（P〉0.05）;化疗结束和化疗后4周,两组Hb水平均低于化疗前（P〈0.05）。化疗前两组VO2max和RPFS得分差异无统计学意义（P〉0.05）;化疗结束和化疗后4周,运动组VO2max和RPFS得分与化疗前相比差异均无统计学意义（P〉0.05）,对照组VO2max低于化疗前水平,RPFS得分高于化疗前水平（均P〈0.05）。结论化疗期间有氧运动能够有效缓解化疗导致癌因性疲乏加重的情况,这可能与有氧运动能对抗VO2max降低有关。
Bibliography:fatigue; neoplasms; physical education and training; hemoglobins; oxygen consumption; cancer-related fatigue; aerobic exercise; VO2max; Piper fatigue scale
Objective To investigate the effects of aerobic exercise during chemotherapy on cancer-related fatigue inbreast cancer patients, and related mechanism thereof. Methods Sixty breast cancer patients who underwent radical surgerywere randomly assigned to exercise group and control group, 30 patients for each group. Patients in exercise group receivedregular nursing care plus aerobic exercise during chemotherapy, while patients in control group only received regular nursingcare. The revised Piper fatigue scale（RPFS） was used to assess the fatigue degree. Values of hemoglobin concentration（Hb）,maximal oxygen uptake（VO2max） and RPFS scores were detected before chemotherapy, at the end of chemotherapy and 4 weeksafter chemotherapy, respectively. Results There was no significant difference in Hb concentration before chemotherapy,at the end of chemotherapy and 4 wee
ISSN:0253-9896
DOI:10.11958/20150195