Anatomical guidance for functional near-infrared spectroscopy: AtlasViewer tutorial

Functional near-infrared spectroscopy (fNIRS) is an optical imaging method that is used to noninvasively measure cerebral hemoglobin concentration changes induced by brain activation. Using structural guidance in fNIRS research enhances interpretation of results and facilitates making comparisons be...

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Published inNeurophotonics (Print) Vol. 2; no. 2; p. 020801
Main Authors Aasted, Christopher M, Yücel, Meryem A, Cooper, Robert J, Dubb, Jay, Tsuzuki, Daisuke, Becerra, Lino, Petkov, Mike P, Borsook, David, Dan, Ippeita, Boas, David A
Format Journal Article
LanguageEnglish
Published United States Society of Photo-Optical Instrumentation Engineers 01.04.2015
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Online AccessGet full text
ISSN2329-423X
2329-4248
2329-4248
DOI10.1117/1.NPh.2.2.020801

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Abstract Functional near-infrared spectroscopy (fNIRS) is an optical imaging method that is used to noninvasively measure cerebral hemoglobin concentration changes induced by brain activation. Using structural guidance in fNIRS research enhances interpretation of results and facilitates making comparisons between studies. AtlasViewer is an open-source software package we have developed that incorporates multiple spatial registration tools to enable structural guidance in the interpretation of fNIRS studies. We introduce the reader to the layout of the AtlasViewer graphical user interface, the folder structure, and user files required in the creation of fNIRS probes containing sources and detectors registered to desired locations on the head, evaluating probe fabrication error and intersubject probe placement variability, and different procedures for estimating measurement sensitivity to different brain regions as well as image reconstruction performance. Further, we detail how AtlasViewer provides a generic head atlas for guiding interpretation of fNIRS results, but also permits users to provide subject-specific head anatomies to interpret their results. We anticipate that AtlasViewer will be a valuable tool in improving the anatomical interpretation of fNIRS studies.
AbstractList Functional near-infrared spectroscopy (fNIRS) is an optical imaging method that is used to noninvasively measure cerebral hemoglobin concentration changes induced by brain activation. Using structural guidance in fNIRS research enhances interpretation of results and facilitates making comparisons between studies. AtlasViewer is an open-source software package we have developed that incorporates multiple spatial registration tools to enable structural guidance in the interpretation of fNIRS studies. We introduce the reader to the layout of the AtlasViewer graphical user interface, the folder structure, and user files required in the creation of fNIRS probes containing sources and detectors registered to desired locations on the head, evaluating probe fabrication error and intersubject probe placement variability, and different procedures for estimating measurement sensitivity to different brain regions as well as image reconstruction performance. Further, we detail how AtlasViewer provides a generic head atlas for guiding interpretation of fNIRS results, but also permits users to provide subject-specific head anatomies to interpret their results. We anticipate that AtlasViewer will be a valuable tool in improving the anatomical interpretation of fNIRS studies.Functional near-infrared spectroscopy (fNIRS) is an optical imaging method that is used to noninvasively measure cerebral hemoglobin concentration changes induced by brain activation. Using structural guidance in fNIRS research enhances interpretation of results and facilitates making comparisons between studies. AtlasViewer is an open-source software package we have developed that incorporates multiple spatial registration tools to enable structural guidance in the interpretation of fNIRS studies. We introduce the reader to the layout of the AtlasViewer graphical user interface, the folder structure, and user files required in the creation of fNIRS probes containing sources and detectors registered to desired locations on the head, evaluating probe fabrication error and intersubject probe placement variability, and different procedures for estimating measurement sensitivity to different brain regions as well as image reconstruction performance. Further, we detail how AtlasViewer provides a generic head atlas for guiding interpretation of fNIRS results, but also permits users to provide subject-specific head anatomies to interpret their results. We anticipate that AtlasViewer will be a valuable tool in improving the anatomical interpretation of fNIRS studies.
Functional near-infrared spectroscopy (fNIRS) is an optical imaging method that is used to noninvasively measure cerebral hemoglobin concentration changes induced by brain activation. Using structural guidance in fNIRS research enhances interpretation of results and facilitates making comparisons between studies. AtlasViewer is an open-source software package we have developed that incorporates multiple spatial registration tools to enable structural guidance in the interpretation of fNIRS studies. We introduce the reader to the layout of the AtlasViewer graphical user interface, the folder structure, and user files required in the creation of fNIRS probes containing sources and detectors registered to desired locations on the head, evaluating probe fabrication error and intersubject probe placement variability, and different procedures for estimating measurement sensitivity to different brain regions as well as image reconstruction performance. Further, we detail how AtlasViewer provides a generic head atlas for guiding interpretation of fNIRS results, but also permits users to provide subject-specific head anatomies to interpret their results. We anticipate that AtlasViewer will be a valuable tool in improving the anatomical interpretation of fNIRS studies.
Author Borsook, David
Tsuzuki, Daisuke
Yücel, Meryem A
Cooper, Robert J
Boas, David A
Aasted, Christopher M
Dan, Ippeita
Dubb, Jay
Becerra, Lino
Petkov, Mike P
Author_xml – sequence: 1
  givenname: Christopher M
  surname: Aasted
  fullname: Aasted, Christopher M
  organization: bDepartment of Anesthesiology, Perioperative, and Pain Medicine, Boston Children's Hospital, 300 Longwood Avenue, Boston, Massachusetts 02115, United States
– sequence: 2
  givenname: Meryem A
  surname: Yücel
  fullname: Yücel, Meryem A
  organization: cDepartment of Radiology, Athinoula Martinos Center for Biomedical Imaging, 149 13th Street, Charlestown, Massachusetts 02129, United States
– sequence: 3
  givenname: Robert J
  surname: Cooper
  fullname: Cooper, Robert J
  organization: dUniversity College London, Department of Medical Physics and Biomedical Engineering, Gower Street, London WC1E 6BT, United Kingdom
– sequence: 4
  givenname: Jay
  surname: Dubb
  fullname: Dubb, Jay
  organization: cDepartment of Radiology, Athinoula Martinos Center for Biomedical Imaging, 149 13th Street, Charlestown, Massachusetts 02129, United States
– sequence: 5
  givenname: Daisuke
  surname: Tsuzuki
  fullname: Tsuzuki, Daisuke
  organization: eChuo University, Faculty of Science and Engineering, 1-13-27 Kasuga, Bunkyo, Tokyo 112-8551, Japan
– sequence: 6
  givenname: Lino
  surname: Becerra
  fullname: Becerra, Lino
  organization: gDepartment of Psychiatry, McLean Hospital, 115 Mill Street, Belmont, Massachusetts 02478, United States
– sequence: 7
  givenname: Mike P
  surname: Petkov
  fullname: Petkov, Mike P
  organization: bDepartment of Anesthesiology, Perioperative, and Pain Medicine, Boston Children's Hospital, 300 Longwood Avenue, Boston, Massachusetts 02115, United States
– sequence: 8
  givenname: David
  surname: Borsook
  fullname: Borsook, David
  organization: gDepartment of Psychiatry, McLean Hospital, 115 Mill Street, Belmont, Massachusetts 02478, United States
– sequence: 9
  givenname: Ippeita
  surname: Dan
  fullname: Dan, Ippeita
  organization: eChuo University, Faculty of Science and Engineering, 1-13-27 Kasuga, Bunkyo, Tokyo 112-8551, Japan
– sequence: 10
  givenname: David A
  surname: Boas
  fullname: Boas, David A
  email: dboas@nmr.mgh.harvard.edu
  organization: cDepartment of Radiology, Athinoula Martinos Center for Biomedical Imaging, 149 13th Street, Charlestown, Massachusetts 02129, United States
BackLink https://www.ncbi.nlm.nih.gov/pubmed/26157991$$D View this record in MEDLINE/PubMed
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Issue 2
Keywords near-infrared spectroscopy
image reconstruction
tutorial
probe design
atlas
photon migration
Language English
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The first two authors contributed equally to this work.
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Snippet Functional near-infrared spectroscopy (fNIRS) is an optical imaging method that is used to noninvasively measure cerebral hemoglobin concentration changes...
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Title Anatomical guidance for functional near-infrared spectroscopy: AtlasViewer tutorial
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