A unified approach for allele frequency estimation, SNP detection and association studies based on pooled sequencing data using EM algorithms - Chen, Quan; Sun, Fengzhu (BMC genomics, 2013)
Keywords: Algorithms; Animal Genetics and Genomics; Bioinformatics; Biomedical and Life Sciences; Databases, Genetic; Diabetes Mellitus, Type 1 - genetics; Disease; Gene Frequency; Genetics; Genome-Wide Association Study; Genomes; Genomics; Genotype; High-Throughput Nucleotide Sequencing; Humans; Hypotheses; Internet; Life Sciences; Methods; Microarrays; Microbial Genetics and Genomics; Plant Genetics and Genomics; Polymorphism, Single Nucleotide; Proceedings; Proteomics; Random variables; Software; Studies; Rare Variant; Expectation Maximization; Minor Allele; Minor Allele Frequency; Mean Square Error