Sophora flavescens Alkaloids and Corticosteroid Synergistically Augment IL-10/IL-5 Ratio with Foxp3-Gene-Epigenetic Modification in Asthma PBMCs - Song, Ying; Wang, Zhen-Zhen; Wang, Lixin; Faybusovich, Paul; Srivastava, Kamal; Liu, Changda; Tversky, Jody; Dunkin, David; Busse, Paula; Ren, Xianqing; Miller, Rachel; Miao, Mingsan; et al. (Journal of asthma and allergy, 2021)
Keywords: Alkaloids; Allergens; Allergies; Antiasthmatic agents; Asthma; CD28 antigen; CD3 antigen; Corticosteroids; CpG islands; Cytokines; Deoxyribonucleic acid; Dexamethasone; DNA; DNA methylation; Drug dosages; Epigenetic inheritance; Epigenetics; Flavonoids; foxp3 methylation; Foxp3 protein; Gene expression; Genes; Herbal medicine; il-10/il-5 ratio; Immunomodulation; Immunomodulators; Immunotherapy; Inflammation; Interleukin 10; Interleukin 5; Lymphocytes; Lymphocytes T; Medicine, Botanic; Medicine, Herbal; Methylation; Original Research; Peripheral blood mononuclear cells; Quality control; Reagents; Remission (Medicine); Sophora flavescens; sophora flavescent; Steroids; synergistic effect; China; asthma; IL-10/IL-5 ratio; Sophora flavescens; foxp3 methylation; synergistic effect