Tuberin regulates reactive oxygen species in renal proximal cells, kidney from rodents, and kidney from patients with tuberous sclerosis complex - Habib, Samy L.; Abboud, Hanna E. (Cancer science, 2016)
Keywords: Animals; Binding sites; Bisindolylmaleimide I; Cancer; Cell culture; Cell growth; Cells, Cultured; CYBB protein; Deoxyribonucleic acid; DNA; DNA damage; Embryo fibroblasts; Embryo, Mammalian - cytology; Embryos; Enzymes; Fibroblasts; Fibroblasts - cytology; Fibroblasts - metabolism; Gene expression; Humans; Isoforms; Kidney; Kidney Cortex - enzymology; Kidney Cortex - metabolism; Kidney Tubules, Proximal - cytology; Kidney Tubules, Proximal - metabolism; Kinases; Male; Mice; Mutation; NAD(P)H oxidase; NADPH Oxidase 1; NADPH Oxidases - genetics; NADPH Oxidases - metabolism; Nox protein; NOX4 protein; Original; Oxidative stress; Prostate; Protein expression; Protein kinase C; Proteins; Rapamycin; Rats; Reactive oxygen species; Reactive Oxygen Species - metabolism; renal cells; Renal cortex; RNA, Messenger - genetics; RNA, Messenger - metabolism; Studies; TOR Serine-Threonine Kinases - antagonists & inhibitors; TOR Serine-Threonine Kinases - metabolism; Tuberous sclerosis; Tuberous Sclerosis - metabolism; Tuberous Sclerosis Complex 2; Tuberous Sclerosis Complex 2 Protein; tumor suppressor gene; Tumor Suppressor Proteins - deficiency; Tumor Suppressor Proteins - metabolism; tumorigenesis; United States--US; tumorigenesis; Kidney; renal cells; tumor suppressor gene; reactive oxygen species