The effect of DPP-4 inhibition with sitagliptin on incretin secretion and on fasting and postprandial glucose turnover in subjects with impaired fasting glucose - Bock, Gerlies; Man, Chiara Dalla; Micheletto, Francesco; Basu, Rita; Giesler, Paula D.; Laugen, Jeanette; Deacon, Carolyn F.; Holst, Jens J.; Toffolo, Gianna; Cobelli, Claudio; Rizza, Robert A.; Vella, Adrian (Clinical endocrinology (Oxford), 2010)
Keywords: Biological and medical sciences; Blood Glucose - drug effects; Blood Glucose - metabolism; Diabetes. Impaired glucose tolerance; Dipeptidyl Peptidase 4 - metabolism; Dipeptidyl-Peptidase IV Inhibitors - pharmacology; Double-Blind Method; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Fasting - blood; Fasting - metabolism; Female; Fundamental and applied biological sciences. Psychology; Glucose Intolerance - blood; Glucose Intolerance - metabolism; Humans; Incretins - blood; Incretins - metabolism; Male; Medical sciences; Middle Aged; Placebos; Postprandial Period - physiology; Pyrazines - pharmacology; Sitagliptin Phosphate; Triazoles - pharmacology; Vertebrates: endocrinology; Dipeptidyl-peptidase IV; Endocrinopathy; Human; Incretin; Enzyme; Secretion; Enzyme inhibitor; Sitagliptin; Glucose; Peptidases; Hypoglycemic agent; Gliptine derivatives; Hydrolases; Dipeptidyl-peptidase IV inhibitor; Inhibition; Fast; Impaired glucose tolerance; Endocrinology; Glycemia