A Phase 1 clinical trial of a DNA vaccine for Venezuelan equine encephalitis delivered by intramuscular or intradermal electroporation - Hannaman, Drew; Dupuy, Lesley C.; Ellefsen, Barry; Schmaljohn, Connie S. (Vaccine, 2016)
Keywords: Adolescent; Adult; Allergy and Immunology; Alphavirus; antibodies; Antibodies, Neutralizing - blood; Antibodies, Viral - blood; Clinical trial; clinical trials; Deoxyribonucleic acid; DNA; DNA vaccine; Double-Blind Method; Electroporation; Encephalitis; Encephalitis Virus, Venezuelan Equine; Encephalomyelitis, Venezuelan Equine - prevention & control; Female; genes; Hispanic Americans; horses; Human; Humans; immune response; Immunogenicity; Immunogenicity, Vaccine; Immunoglobulins; Injection; Injections, Intradermal; Injections, Intramuscular; Intradermal; Intramuscular; Male; Middle Aged; Phase 1; questionnaires; R&D; recombinant vaccines; Reoviridae; Research & development; Studies; Togaviridae; Vaccines; Vaccines, DNA - administration & dosage; Vaccines, DNA - therapeutic use; Venezuelan equine encephalitis; Venezuelan equine encephalitis virus; Viral Vaccines - administration & dosage; Viral Vaccines - therapeutic use; Young Adult; DNA vaccine; Human; Intradermal; Venezuelan equine encephalitis; Electroporation; Clinical trial; Intramuscular; Phase 1