A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression - Carrasquillo, Minerva M; Allen, Mariet; Burgess, Jeremy D; Wang, Xue; Strickland, Samantha L; Aryal, Shivani; Siuda, Joanna; Kachadoorian, Michaela L; Medway, Christopher; Younkin, Curtis S; Nair, Asha; Wang, Chen; et al. (Alzheimer's & dementia, 2017)
Keywords: Aged; Aged, 80 and over; Alzheimer Disease - genetics; Alzheimer Disease - metabolism; Alzheimer's disease; Cerebellum - metabolism; eQTL; Female; Gene Expression; Genetic Predisposition to Disease; Genetic Variation; Humans; Linkage Disequilibrium; Male; Membrane Glycoproteins - genetics; Membrane Glycoproteins - metabolism; Microarray Analysis; Multigene Family; Neurology; Quantitative Trait Loci; Receptors, Immunologic - genetics; Receptors, Immunologic - metabolism; Regulatory variant; Temporal Lobe - metabolism; TREM2; TREML1; TREML1; Regulatory variant; TREM2; eQTL; Alzheimer's disease