Auxin signaling modules regulate maize inflorescence architecture

In plants, small groups of pluripotent stem cells called axillary meristems are required for the formation of the branches and flowers that eventually establish shoot architecture and drive reproductive success. To ensure the proper formation of new axillary meristems, the specification of boundary...

Full description

Saved in:

Bibliographic Details
Published in	Proceedings of the National Academy of Sciences - PNAS Vol. 112; no. 43; pp. 13372 - 13377
Main Authors	Galli, Mary, Liu, Qiujie, Moss, Britney L., Malcomber, Simon, Li, Wei, Gaines, Craig, Federici, Silvia, Roshkovan, Jessica, Meeley, Robert, Nemhauser, Jennifer L., Gallavotti, Andrea
Format	Journal Article
Language	English
Published	United States National Academy of Sciences 27.10.2015 National Acad Sciences
Subjects	Acetic acid Bayes Theorem Biological Sciences Cloning, Molecular Computational Biology Corn DNA Primers - genetics Electrophoretic Mobility Shift Assay Flowers - cytology Flowers - growth & development Gene Expression Regulation, Developmental - genetics Gene Expression Regulation, Developmental - physiology Gene Expression Regulation, Plant - genetics Gene Expression Regulation, Plant - physiology Genetics Hormones In Situ Hybridization Indoleacetic Acids - metabolism Meristem - growth & development Meristem - metabolism Models, Genetic Phylogeny Plant Proteins - genetics Plant Proteins - metabolism Plant reproduction Protein expression Real-Time Polymerase Chain Reaction Reproduction Signal transduction Signal Transduction - physiology Stem cells Zea mays Zea mays - growth & development boundary domains inflorescence development axillary meristems maize auxin signaling
Online Access	Get full text
ISSN	0027-8424 1091-6490 1091-6490
DOI	10.1073/pnas.1516473112

Cover

Abstract	In plants, small groups of pluripotent stem cells called axillary meristems are required for the formation of the branches and flowers that eventually establish shoot architecture and drive reproductive success. To ensure the proper formation of new axillary meristems, the specification of boundary regions is required for coordinating their development. We have identified two maize genes,BARREN INFLORESCENCE1andBARREN INFLORESCENCE4(BIF1andBIF4), that regulate the early steps required for inflorescence formation.BIF1andBIF4encode AUXIN/INDOLE-3-ACETIC ACID (Aux/IAA) proteins, which are key components of the auxin hormone signaling pathway that is essential for organogenesis. Here we show that BIF1 and BIF4 are integral to auxin signaling modules that dynamically regulate the expression of BARREN STALK1 (BA1), a basic helix-loop-helix (bHLH) transcriptional regulator necessary for axillary meristem formation that shows a striking boundary expression pattern. These findings suggest that auxin signaling directly controls boundary domains during axillary meristem formation and define a fundamental mechanism that regulates inflorescence architecture in one of the most widely grown crop species.
AbstractList	Axillary meristems are groups of plant pluripotent stem cells responsible for the formation of secondary axes of growth, such as branches and flowers. A crucial step in the initiation of new axillary meristems is the establishment of boundary domains that allow organ separation and prevent fusion defects during development. This work provides clues on the molecular mechanism by which the plant hormone auxin is involved in the formation of axillary meristems in maize inflorescences. Auxin signaling modules containing the AUXIN/INDOLE-3-ACETIC ACID proteins BARREN INFLORESCENCE1 and BARREN INFLORESCENCE4 and AUXIN RESPONSE FACTOR (ARF) transcriptional regulators are involved in the regulation of the boundary basic helix-loop-helix transcription factor BARREN STALK1, suggesting auxin is directly responsible for establishing boundary regions. In plants, small groups of pluripotent stem cells called axillary meristems are required for the formation of the branches and flowers that eventually establish shoot architecture and drive reproductive success. To ensure the proper formation of new axillary meristems, the specification of boundary regions is required for coordinating their development. We have identified two maize genes, BARREN INFLORESCENCE1 and BARREN INFLORESCENCE4 ( BIF1 and BIF4 ), that regulate the early steps required for inflorescence formation. BIF1 and BIF4 encode AUXIN/INDOLE-3-ACETIC ACID (Aux/IAA) proteins, which are key components of the auxin hormone signaling pathway that is essential for organogenesis. Here we show that BIF1 and BIF4 are integral to auxin signaling modules that dynamically regulate the expression of BARREN STALK1 (BA1), a basic helix-loop-helix (bHLH) transcriptional regulator necessary for axillary meristem formation that shows a striking boundary expression pattern. These findings suggest that auxin signaling directly controls boundary domains during axillary meristem formation and define a fundamental mechanism that regulates inflorescence architecture in one of the most widely grown crop species. In plants, small groups of pluripotent stem cells called axillary meristems are required for the formation of the branches and flowers that eventually establish shoot architecture and drive reproductive success. To ensure the proper formation of new axillary meristems, the specification of boundary regions is required for coordinating their development. We have identified two maize genes,BARREN INFLORESCENCE1andBARREN INFLORESCENCE4(BIF1andBIF4), that regulate the early steps required for inflorescence formation.BIF1andBIF4encode AUXIN/INDOLE-3-ACETIC ACID (Aux/IAA) proteins, which are key components of the auxin hormone signaling pathway that is essential for organogenesis. Here we show that BIF1 and BIF4 are integral to auxin signaling modules that dynamically regulate the expression of BARREN STALK1 (BA1), a basic helix-loop-helix (bHLH) transcriptional regulator necessary for axillary meristem formation that shows a striking boundary expression pattern. These findings suggest that auxin signaling directly controls boundary domains during axillary meristem formation and define a fundamental mechanism that regulates inflorescence architecture in one of the most widely grown crop species. In plants, small groups of pluripotent stem cells called axillary meristems are required for the formation of the branches and flowers that eventually establish shoot architecture and drive reproductive success. To ensure the proper formation of new axillary meristems, the specification of boundary regions is required for coordinating their development. We have identified two maize genes, BARREN INFLORESCENCE1 and BARREN INFLORESCENCE4 (BIF1 and BIF4), that regulate the early steps required for inflorescence formation. BIF1 and BIF4 encode AUXIN/INDOLE-3-ACETIC ACID (Aux/IAA) proteins, which are key components of the auxin hormone signaling pathway that is essential for organogenesis. Here we show that BIF1 and BIF4 are integral to auxin signaling modules that dynamically regulate the expression of BARREN STALK1 (BA1), a basic helix-loop-helix (bHLH) transcriptional regulator necessary for axillary meristem formation that shows a striking boundary expression pattern. These findings suggest that auxin signaling directly controls boundary domains during axillary meristem formation and define a fundamental mechanism that regulates inflorescence architecture in one of the most widely grown crop species. Axillary meristems are groups of plant pluripotent stem cells responsible for the formation of secondary axes of growth, such as branches and flowers. A crucial step in the initiation of new axillary meristems is the establishment of boundary domains that allow organ separation and prevent fusion defects during development. This work provides clues on the molecular mechanism by which the plant hormone auxin is involved in the formation of axillary meristems in maize inflorescences. Auxin signaling modules containing the AUXIN/INDOLE-3-ACETIC ACID proteins BARREN INFLORESCENCE1 and BARREN INFLORESCENCE4 and AUXIN RESPONSE FACTOR (ARF) transcriptional regulators are involved in the regulation of the boundary basic helix-loop-helix transcription factor BARREN STALK1, suggesting auxin is directly responsible for establishing boundary regions. In plants, small groups of pluripotent stem cells called axillary meristems are required for the formation of the branches and flowers that eventually establish shoot architecture and drive reproductive success. To ensure the proper formation of new axillary meristems, the specification of boundary regions is required for coordinating their development. We have identified two maize genes, BARREN INFLORESCENCE1 and BARREN INFLORESCENCE4 (BIF1 and BIF4), that regulate the early steps required for inflorescence formation. BIF1 and BIF4 encode AUXIN/INDOLE-3-ACETIC ACID (Aux/IAA) proteins, which are key components of the auxin hormone signaling pathway that is essential for organogenesis. Here we show that BIF1 and BIF4 are integral to auxin signaling modules that dynamically regulate the expression of BARREN STALK1 (BA1), a basic helix-loop-helix (bHLH) transcriptional regulator necessary for axillary meristem formation that shows a striking boundary expression pattern. These findings suggest that auxin signaling directly controls boundary domains during axillary meristem formation and define a fundamental mechanism that regulates inflorescence architecture in one of the most widely grown crop species.
Author	Moss, Britney L. Gaines, Craig Galli, Mary Meeley, Robert Malcomber, Simon Liu, Qiujie Li, Wei Federici, Silvia Roshkovan, Jessica Nemhauser, Jennifer L. Gallavotti, Andrea
Author_xml	– sequence: 1 givenname: Mary surname: Galli fullname: Galli, Mary organization: Waksman Institute, Rutgers University, Piscataway, NJ 08854-8020 – sequence: 2 givenname: Qiujie surname: Liu fullname: Liu, Qiujie organization: Waksman Institute, Rutgers University, Piscataway, NJ 08854-8020 – sequence: 3 givenname: Britney L. surname: Moss fullname: Moss, Britney L. organization: Department of Biology, University of Washington, Seattle, WA 98195 – sequence: 4 givenname: Simon surname: Malcomber fullname: Malcomber, Simon organization: Division of Environmental Biology, National Science Foundation, Arlington, VA 22230 – sequence: 5 givenname: Wei surname: Li fullname: Li, Wei organization: Waksman Institute, Rutgers University, Piscataway, NJ 08854-8020 – sequence: 6 givenname: Craig surname: Gaines fullname: Gaines, Craig organization: Section of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA 92093-0116 – sequence: 7 givenname: Silvia surname: Federici fullname: Federici, Silvia organization: Waksman Institute, Rutgers University, Piscataway, NJ 08854-8020 – sequence: 8 givenname: Jessica surname: Roshkovan fullname: Roshkovan, Jessica organization: Waksman Institute, Rutgers University, Piscataway, NJ 08854-8020 – sequence: 9 givenname: Robert surname: Meeley fullname: Meeley, Robert organization: Pioneer Hi-Bred International, Johnston, IA 50131 – sequence: 10 givenname: Jennifer L. surname: Nemhauser fullname: Nemhauser, Jennifer L. organization: Department of Biology, University of Washington, Seattle, WA 98195 – sequence: 11 givenname: Andrea surname: Gallavotti fullname: Gallavotti, Andrea organization: Waksman Institute, Rutgers University, Piscataway, NJ 08854-8020
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/26464512$$D View this record in MEDLINE/PubMed
BookMark	eNqNkTtvFDEURi0URDaBmgo0Eg3NJH6Nx26QVhGPSJFoQm3d9Xg2XnnsxZ4JhF-Ph13yKiCVi3u-68_HR-ggxGARek3wCcEtO90GyCekIYK3jBD6DC0IVqQWXOEDtMCYtrXklB-io5w3GGPVSPwCHVLBBW8IXaDlcvrpQpXdOoB3YV0NsZu8zVWy68nDaKsB3C9budD7mGw2NhhbQTJXbrRmnJJ9iZ734LN9tT-P0bdPHy_PvtQXXz-fny0vatOIdqxlawi3QkkG0q6UNIy1K0yB9p3ijHS9gr4gpqemE1JSu5IALYXeCiNVw9gxwru9U9jCzQ_wXm-TGyDdaIL1bEPPNvSdjRL5sItsp9Vgu9J9THAXi-D0w0lwV3odrzUXVDEqyoL3-wUpfp9sHvXgigLvIdg4lbtaXrqShqsnoFTSYqIhBX33CN3EKRX_fyhFqKCMF-rt_fK3rf_-XQGaHWBSzDnZXhs3wuji_Bbn_2Hl9FHu_x6rfZV5cEsTqjnTpHzkjLzZIZs8xvSgbNNKyn4DiObRvA
CitedBy_id	crossref_primary_10_1186_s12864_024_11186_1 crossref_primary_10_1111_pbi_13702 crossref_primary_10_3390_cells11111753 crossref_primary_10_1007_s10725_022_00941_7 crossref_primary_10_1111_pbi_13267 crossref_primary_10_1016_j_gene_2020_144928 crossref_primary_10_1038_s41467_020_14746_7 crossref_primary_10_1038_s41477_020_0739_7 crossref_primary_10_1002_dvg_23307 crossref_primary_10_1016_j_cj_2023_03_010 crossref_primary_10_3389_fpls_2021_666075 crossref_primary_10_1002_cpz1_562 crossref_primary_10_1016_j_xplc_2023_100670 crossref_primary_10_1038_s41467_021_22699_8 crossref_primary_10_1111_ppl_13670 crossref_primary_10_1007_s11676_017_0414_7 crossref_primary_10_1038_s41598_020_66860_7 crossref_primary_10_1093_plcell_koab134 crossref_primary_10_1093_plphys_kiae476 crossref_primary_10_1186_s12864_017_3722_6 crossref_primary_10_1111_tpj_15961 crossref_primary_10_1038_s41598_024_76568_7 crossref_primary_10_1038_s41477_022_01121_1 crossref_primary_10_1111_pce_14438 crossref_primary_10_1093_jxb_erad372 crossref_primary_10_3389_fpls_2017_00256 crossref_primary_10_3390_ijms23094886 crossref_primary_10_1007_s10528_019_09919_z crossref_primary_10_1007_s11032_021_01212_5 crossref_primary_10_1093_pcp_pcy022 crossref_primary_10_1016_j_jare_2022_01_012 crossref_primary_10_1111_tpj_15096 crossref_primary_10_1007_s00122_023_04385_z crossref_primary_10_1534_genetics_117_300092 crossref_primary_10_1093_jxb_erad288 crossref_primary_10_1016_j_cub_2024_04_029 crossref_primary_10_1007_s10722_024_02066_4 crossref_primary_10_1016_j_pbi_2017_09_001 crossref_primary_10_1038_s41477_022_01190_2 crossref_primary_10_1111_eva_70047 crossref_primary_10_1111_tpj_13996 crossref_primary_10_3390_ijms24010189 crossref_primary_10_1007_s11295_018_1312_7 crossref_primary_10_1007_s00122_021_04018_3 crossref_primary_10_1016_j_copbio_2024_103194 crossref_primary_10_3390_ijms241612718 crossref_primary_10_1038_s41467_023_41022_1 crossref_primary_10_1371_journal_pone_0203728 crossref_primary_10_1002_jpln_202300155 crossref_primary_10_3390_ijms24021182 crossref_primary_10_1016_j_pbi_2018_04_010 crossref_primary_10_1016_j_pbi_2020_101998 crossref_primary_10_1007_s00122_019_03357_6 crossref_primary_10_1093_genetics_iyaf012 crossref_primary_10_1134_S002689332002017X crossref_primary_10_1016_j_scienta_2019_03_064 crossref_primary_10_1007_s11240_017_1336_y crossref_primary_10_1016_j_molp_2023_12_014 crossref_primary_10_1093_jxb_erw422 crossref_primary_10_1186_s12870_018_1441_z crossref_primary_10_1093_jxb_ery204 crossref_primary_10_1016_j_genrep_2021_101464 crossref_primary_10_1073_pnas_1907071116 crossref_primary_10_1007_s00122_019_03436_8 crossref_primary_10_1007_s11829_017_9562_0 crossref_primary_10_1016_j_molp_2018_12_024 crossref_primary_10_1007_s12042_019_09227_1 crossref_primary_10_1073_pnas_1701536114 crossref_primary_10_1038_s41467_021_26123_z crossref_primary_10_1093_plcell_koac093 crossref_primary_10_1007_s00497_024_00510_0 crossref_primary_10_1111_nph_14391 crossref_primary_10_1007_s00427_016_0572_1 crossref_primary_10_1111_jipb_13570 crossref_primary_10_1093_g3journal_jkae161 crossref_primary_10_1016_j_ncrops_2024_100053 crossref_primary_10_1080_15592324_2021_1891756 crossref_primary_10_1016_j_jgg_2025_01_012 crossref_primary_10_1101_cshperspect_a034652 crossref_primary_10_1111_nph_19329 crossref_primary_10_1093_plphys_kiac424 crossref_primary_10_1111_jipb_13603 crossref_primary_10_1111_tpj_16851 crossref_primary_10_1093_plphys_kiac099 crossref_primary_10_1111_tpj_16457 crossref_primary_10_1093_jxb_erad297 crossref_primary_10_1007_s00425_023_04126_y crossref_primary_10_1186_s12864_019_6418_2 crossref_primary_10_3389_fpls_2024_1369074 crossref_primary_10_1038_s41467_024_46955_9 crossref_primary_10_1017_qpb_2022_17 crossref_primary_10_3390_cells12141900 crossref_primary_10_1007_s10722_019_00805_6 crossref_primary_10_1038_s41477_021_01029_2 crossref_primary_10_1093_plcell_koac352 crossref_primary_10_1111_nph_17882 crossref_primary_10_1007_s11032_023_01426_9 crossref_primary_10_1111_tpj_15299 crossref_primary_10_1038_s41467_018_06977_6 crossref_primary_10_1016_j_cell_2016_04_038 crossref_primary_10_3390_cells10102601 crossref_primary_10_3389_fpls_2024_1398818 crossref_primary_10_1007_s00425_016_2607_2 crossref_primary_10_1038_s41477_024_01683_2 crossref_primary_10_1007_s11103_022_01298_1 crossref_primary_10_1534_g3_118_200551 crossref_primary_10_1101_cshperspect_a039925 crossref_primary_10_1038_s41588_024_01943_z crossref_primary_10_1007_s10725_018_0412_6 crossref_primary_10_1016_j_molp_2018_12_012 crossref_primary_10_3389_fpls_2024_1441288 crossref_primary_10_1093_plcell_koac081 crossref_primary_10_1093_plcell_koac080 crossref_primary_10_1016_j_molp_2024_06_007 crossref_primary_10_3389_fpls_2023_1183697 crossref_primary_10_3390_ijms25158154 crossref_primary_10_1371_journal_pgen_1010698 crossref_primary_10_1093_plphys_kiac115 crossref_primary_10_1515_hsz_2018_0310 crossref_primary_10_1016_j_jia_2023_10_030
Cites_doi	10.1104/pp.108.121541 10.1105/tpc.110.075267 10.1105/tpc.13.3.465 10.1186/1471-2164-12-178 10.1007/s11103-012-9917-y 10.1016/j.cell.2013.12.027 10.1073/pnas.1400074111 10.1038/nature08836 10.1101/gad.193433.112 10.1038/nature03148 10.1242/dev.048348 10.1016/j.devcel.2012.12.017 10.1534/genetics.107.084079 10.1104/pp.104.039669 10.1046/j.0960-7412.2001.01201.x 10.1186/1471-2105-5-113 10.1046/j.1365-313x.1996.10030403.x 10.1016/j.plantsci.2012.04.003 10.1104/pp.112.202184 10.1073/pnas.1015162108 10.1126/science.282.5397.2226 10.1104/pp.107.096628 10.1038/ng.2534 10.1105/tpc.106.047761 10.1242/dev.051748 10.1186/1471-2164-8-116 10.1101/gr.166397.113 10.1016/j.cub.2005.09.052 10.1104/pp.107.098558 10.1105/tpc.114.123059 10.1104/pp.000653 10.1073/pnas.0805596105 10.1038/ng.3131 10.1007/BF00208313 10.1242/dev.01388 10.1038/nmeth.1318 10.1073/pnas.1324147111 10.1371/journal.pone.0078859 10.1016/j.cell.2006.12.006 10.1105/tpc.114.123083 10.1093/emboj/17.5.1405 10.1016/S0092-8674(03)00924-3 10.1105/tpc.114.133744 10.1126/science.aaa0196 10.1105/tpc.109.073536 10.1093/bioinformatics/btr088 10.1126/science.1203877 10.1073/pnas.1421878112 10.1105/tpc.111.084590 10.1038/ncomms4617 10.1038/sj.emboj.7600659 10.1104/pp.123.2.563 10.1111/tpj.12623 10.1093/sysbio/sys029 10.1038/msb.2011.39 10.7554/eLife.03031
ContentType	Journal Article
Copyright	Volumes 1–89 and 106–112, copyright as a collective work only; author(s) retains copyright to individual articles Copyright National Academy of Sciences Oct 27, 2015
Copyright_xml	– notice: Volumes 1–89 and 106–112, copyright as a collective work only; author(s) retains copyright to individual articles – notice: Copyright National Academy of Sciences Oct 27, 2015
DBID	AAYXX CITATION CGR CUY CVF ECM EIF NPM 7QG 7QL 7QP 7QR 7SN 7SS 7T5 7TK 7TM 7TO 7U9 8FD C1K FR3 H94 M7N P64 RC3 7X8 7ST SOI 5PM ADTOC UNPAY
DOI	10.1073/pnas.1516473112
DatabaseName	CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Animal Behavior Abstracts Bacteriology Abstracts (Microbiology B) Calcium & Calcified Tissue Abstracts Chemoreception Abstracts Ecology Abstracts Entomology Abstracts (Full archive) Immunology Abstracts Neurosciences Abstracts Nucleic Acids Abstracts Oncogenes and Growth Factors Abstracts Virology and AIDS Abstracts Technology Research Database Environmental Sciences and Pollution Management Engineering Research Database AIDS and Cancer Research Abstracts Algology Mycology and Protozoology Abstracts (Microbiology C) Biotechnology and BioEngineering Abstracts Genetics Abstracts MEDLINE - Academic Environment Abstracts Environment Abstracts PubMed Central (Full Participant titles) Unpaywall for CDI: Periodical Content Unpaywall
DatabaseTitle	CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Virology and AIDS Abstracts Oncogenes and Growth Factors Abstracts Technology Research Database Nucleic Acids Abstracts Ecology Abstracts Neurosciences Abstracts Biotechnology and BioEngineering Abstracts Environmental Sciences and Pollution Management Entomology Abstracts Genetics Abstracts Animal Behavior Abstracts Bacteriology Abstracts (Microbiology B) Algology Mycology and Protozoology Abstracts (Microbiology C) AIDS and Cancer Research Abstracts Chemoreception Abstracts Immunology Abstracts Engineering Research Database Calcium & Calcified Tissue Abstracts MEDLINE - Academic Environment Abstracts
DatabaseTitleList	CrossRef MEDLINE Virology and AIDS Abstracts Ecology Abstracts MEDLINE - Academic
Database_xml	– sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 3 dbid: UNPAY name: Unpaywall url: https://proxy.k.utb.cz/login?url=https://unpaywall.org/ sourceTypes: Open Access Repository
DeliveryMethod	fulltext_linktorsrc
Discipline	Sciences (General)
DocumentTitleAlternate	Auxin signaling in maize inflorescences
EISSN	1091-6490
EndPage	13377
ExternalDocumentID	10.1073/pnas.1516473112 PMC4629326 3855023821 26464512 10_1073_pnas_1516473112 112_43_13372 26465782
Genre	Research Support, U.S. Gov't, Non-P.H.S Research Support, Non-U.S. Gov't Journal Article Research Support, N.I.H., Extramural Feature
GrantInformation_xml	– fundername: NIGMS NIH HHS grantid: R01 GM107084 – fundername: NIGMS NIH HHS grantid: R01-GM107084 – fundername: NCI NIH HHS grantid: F32CA180514 – fundername: NCI NIH HHS grantid: F32 CA180514 – fundername: National Science Foundation (NSF) grantid: 1114484 – fundername: HHS \| National Institutes of Health (NIH) grantid: GM107084 – fundername: HHS \| National Institutes of Health (NIH) grantid: F32CA180514 – fundername: National Science Foundation (NSF) grantid: 1411949
GroupedDBID	--- -DZ -~X .55 0R~ 123 29P 2AX 2FS 2WC 4.4 53G 5RE 5VS 85S AACGO AAFWJ AANCE ABBHK ABOCM ABPLY ABPPZ ABTLG ABXSQ ABZEH ACGOD ACHIC ACIWK ACNCT ACPRK ADQXQ ADULT AENEX AEUPB AEXZC AFFNX AFOSN AFRAH ALMA_UNASSIGNED_HOLDINGS AQVQM BKOMP CS3 D0L DCCCD DIK DU5 E3Z EBS EJD F5P FRP GX1 H13 HH5 HYE IPSME JAAYA JBMMH JENOY JHFFW JKQEH JLS JLXEF JPM JSG JST KQ8 L7B LU7 N9A N~3 O9- OK1 PNE PQQKQ R.V RHI RNA RNS RPM RXW SA0 SJN TAE TN5 UKR W8F WH7 WOQ WOW X7M XSW Y6R YBH YKV YSK ZCA ~02 ~KM - 02 0R 1AW 55 AAPBV ABFLS ABPTK ADACO ADZLD ASUFR DNJUQ DOOOF DWIUU DZ F20 JSODD KM PQEST RHF VQA X XHC ZA5 AAYXX CITATION CGR CUY CVF ECM EIF NPM 7QG 7QL 7QP 7QR 7SN 7SS 7T5 7TK 7TM 7TO 7U9 8FD C1K FR3 H94 M7N P64 RC3 7X8 7ST SOI 5PM .GJ 3O- 692 6TJ 79B AAYJJ ACKIV ADTOC ADXHL AFHIN AFQQW AS~ HGD HQ3 HTVGU MVM NEJ NHB P-O UNPAY VOH WHG ZCG
ID	FETCH-LOGICAL-c567t-87c14e6983a8eb98c337b02a2fd9431df9af7c1cf2cd6882eb8aa72afe6c89533
IEDL.DBID	UNPAY
ISSN	0027-8424 1091-6490
IngestDate	Wed Oct 01 16:22:45 EDT 2025 Tue Sep 30 15:47:17 EDT 2025 Fri Sep 05 06:28:31 EDT 2025 Fri Sep 05 11:43:46 EDT 2025 Mon Jun 30 08:34:05 EDT 2025 Thu Apr 03 06:54:14 EDT 2025 Thu Apr 24 22:55:12 EDT 2025 Wed Oct 01 02:36:54 EDT 2025 Wed Nov 11 00:29:31 EST 2020 Fri May 30 12:01:38 EDT 2025
IsDoiOpenAccess	true
IsOpenAccess	true
IsPeerReviewed	true
IsScholarly	true
Issue	43
Keywords	boundary domains inflorescence development axillary meristems maize auxin signaling
Language	English
LinkModel	DirectLink
MergedId	FETCHMERGED-LOGICAL-c567t-87c14e6983a8eb98c337b02a2fd9431df9af7c1cf2cd6882eb8aa72afe6c89533
Notes	SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 14 ObjectType-Article-1 ObjectType-Feature-2 content type line 23 Author contributions: M.G., B.L.M., S.M., J.L.N., and A.G. designed research; M.G., Q.L., B.L.M., S.M., W.L., C.G., S.F., J.R., and A.G. performed research; R.M. contributed new reagents/analytic tools; M.G., Q.L., B.L.M., S.M., J.L.N., and A.G. analyzed data; and M.G., B.L.M., S.M., and A.G. wrote the paper. Edited by Mark Estelle, University of California, San Diego, La Jolla, CA, and approved September 18, 2015 (received for review August 19, 2015) 1M.G. and Q.L. contributed equally to this work.
OpenAccessLink	https://proxy.k.utb.cz/login?url=https://www.pnas.org/content/pnas/112/43/13372.full.pdf
PMID	26464512
PQID	1729126234
PQPubID	42026
PageCount	6
ParticipantIDs	pubmedcentral_primary_oai_pubmedcentral_nih_gov_4629326 proquest_miscellaneous_1728256751 crossref_primary_10_1073_pnas_1516473112 unpaywall_primary_10_1073_pnas_1516473112 proquest_journals_1729126234 crossref_citationtrail_10_1073_pnas_1516473112 pubmed_primary_26464512 pnas_primary_112_43_13372 proquest_miscellaneous_1746881549 jstor_primary_26465782
ProviderPackageCode	RNA PNE CITATION AAYXX
PublicationCentury	2000
PublicationDate	2015-10-27
PublicationDateYYYYMMDD	2015-10-27
PublicationDate_xml	– month: 10 year: 2015 text: 2015-10-27 day: 27
PublicationDecade	2010
PublicationPlace	United States
PublicationPlace_xml	– name: United States – name: Washington
PublicationTitle	Proceedings of the National Academy of Sciences - PNAS
PublicationTitleAlternate	Proc Natl Acad Sci U S A
PublicationYear	2015
Publisher	National Academy of Sciences National Acad Sciences
Publisher_xml	– name: National Academy of Sciences – name: National Acad Sciences
References	e_1_3_3_50_2 e_1_3_3_16_2 Guseman JM (e_1_3_3_47_2) 2015; 142 e_1_3_3_18_2 e_1_3_3_39_2 e_1_3_3_12_2 e_1_3_3_37_2 e_1_3_3_58_2 e_1_3_3_14_2 e_1_3_3_35_2 e_1_3_3_33_2 e_1_3_3_54_2 e_1_3_3_10_2 e_1_3_3_31_2 e_1_3_3_52_2 e_1_3_3_40_2 e_1_3_3_61_2 Ripoll JJ (e_1_3_3_13_2) 2015 e_1_3_3_5_2 e_1_3_3_7_2 e_1_3_3_9_2 e_1_3_3_27_2 e_1_3_3_29_2 e_1_3_3_23_2 e_1_3_3_48_2 e_1_3_3_25_2 e_1_3_3_46_2 e_1_3_3_1_2 e_1_3_3_44_2 e_1_3_3_3_2 e_1_3_3_21_2 e_1_3_3_42_2 e_1_3_3_51_2 e_1_3_3_17_2 e_1_3_3_19_2 e_1_3_3_38_2 e_1_3_3_36_2 e_1_3_3_59_2 e_1_3_3_15_2 e_1_3_3_34_2 Bensen RJ (e_1_3_3_49_2) 1995; 7 e_1_3_3_57_2 e_1_3_3_32_2 e_1_3_3_55_2 e_1_3_3_11_2 e_1_3_3_30_2 e_1_3_3_53_2 Jones DT (e_1_3_3_56_2) 1992; 8 e_1_3_3_60_2 e_1_3_3_6_2 e_1_3_3_8_2 e_1_3_3_28_2 e_1_3_3_26_2 e_1_3_3_45_2 e_1_3_3_2_2 e_1_3_3_20_2 e_1_3_3_43_2 Neuffer M (e_1_3_3_24_2) 1997 e_1_3_3_4_2 e_1_3_3_22_2 e_1_3_3_41_2
References_xml	– ident: e_1_3_3_26_2 doi: 10.1104/pp.108.121541 – ident: e_1_3_3_23_2 doi: 10.1105/tpc.110.075267 – ident: e_1_3_3_33_2 doi: 10.1105/tpc.13.3.465 – ident: e_1_3_3_53_2 doi: 10.1186/1471-2164-12-178 – ident: e_1_3_3_38_2 doi: 10.1007/s11103-012-9917-y – ident: e_1_3_3_17_2 doi: 10.1016/j.cell.2013.12.027 – ident: e_1_3_3_19_2 doi: 10.1073/pnas.1400074111 – ident: e_1_3_3_9_2 doi: 10.1038/nature08836 – ident: e_1_3_3_51_2 doi: 10.1101/gad.193433.112 – ident: e_1_3_3_20_2 doi: 10.1038/nature03148 – ident: e_1_3_3_46_2 doi: 10.1242/dev.048348 – ident: e_1_3_3_10_2 doi: 10.1016/j.devcel.2012.12.017 – ident: e_1_3_3_25_2 doi: 10.1534/genetics.107.084079 – ident: e_1_3_3_61_2 doi: 10.1104/pp.104.039669 – ident: e_1_3_3_36_2 doi: 10.1046/j.0960-7412.2001.01201.x – ident: e_1_3_3_54_2 doi: 10.1186/1471-2105-5-113 – ident: e_1_3_3_35_2 doi: 10.1046/j.1365-313x.1996.10030403.x – ident: e_1_3_3_16_2 doi: 10.1016/j.plantsci.2012.04.003 – ident: e_1_3_3_29_2 doi: 10.1104/pp.112.202184 – ident: e_1_3_3_40_2 doi: 10.1073/pnas.1015162108 – ident: e_1_3_3_4_2 doi: 10.1126/science.282.5397.2226 – volume: 142 start-page: 905 year: 2015 ident: e_1_3_3_47_2 article-title: Auxin-induced degradation dynamics set the pace for lateral root development publication-title: Development – ident: e_1_3_3_37_2 doi: 10.1104/pp.107.096628 – ident: e_1_3_3_2_2 doi: 10.1038/ng.2534 – ident: e_1_3_3_8_2 doi: 10.1105/tpc.106.047761 – ident: e_1_3_3_31_2 doi: 10.1242/dev.051748 – ident: e_1_3_3_48_2 doi: 10.1186/1471-2164-8-116 – ident: e_1_3_3_52_2 doi: 10.1101/gr.166397.113 – volume: 7 start-page: 75 year: 1995 ident: e_1_3_3_49_2 article-title: Cloning and characterization of the maize An1 gene publication-title: Plant Cell – volume-title: Mutants of Maize. 1997 year: 1997 ident: e_1_3_3_24_2 – ident: e_1_3_3_42_2 doi: 10.1016/j.cub.2005.09.052 – ident: e_1_3_3_21_2 doi: 10.1104/pp.107.098558 – ident: e_1_3_3_43_2 doi: 10.1105/tpc.114.123059 – ident: e_1_3_3_59_2 doi: 10.1104/pp.000653 – ident: e_1_3_3_22_2 doi: 10.1073/pnas.0805596105 – ident: e_1_3_3_3_2 doi: 10.1038/ng.3131 – ident: e_1_3_3_5_2 doi: 10.1007/BF00208313 – ident: e_1_3_3_39_2 doi: 10.1242/dev.01388 – ident: e_1_3_3_58_2 doi: 10.1038/nmeth.1318 – ident: e_1_3_3_30_2 doi: 10.1073/pnas.1324147111 – ident: e_1_3_3_27_2 doi: 10.1371/journal.pone.0078859 – ident: e_1_3_3_1_2 doi: 10.1016/j.cell.2006.12.006 – volume: 8 start-page: 275 year: 1992 ident: e_1_3_3_56_2 article-title: The rapid generation of mutation data matrices from protein sequences publication-title: Comput Appl Biosci – ident: e_1_3_3_45_2 doi: 10.1105/tpc.114.123083 – year: 2015 ident: e_1_3_3_13_2 article-title: microRNA regulation of fruit growth publication-title: Nature Plants – ident: e_1_3_3_6_2 doi: 10.1093/emboj/17.5.1405 – ident: e_1_3_3_41_2 doi: 10.1016/S0092-8674(03)00924-3 – ident: e_1_3_3_7_2 doi: 10.1105/tpc.114.133744 – ident: e_1_3_3_12_2 doi: 10.1126/science.aaa0196 – ident: e_1_3_3_32_2 doi: 10.1105/tpc.109.073536 – ident: e_1_3_3_55_2 doi: 10.1093/bioinformatics/btr088 – ident: e_1_3_3_60_2 doi: 10.1126/science.1203877 – ident: e_1_3_3_44_2 doi: 10.1073/pnas.1421878112 – ident: e_1_3_3_50_2 doi: 10.1105/tpc.111.084590 – ident: e_1_3_3_18_2 doi: 10.1038/ncomms4617 – ident: e_1_3_3_14_2 doi: 10.1038/sj.emboj.7600659 – ident: e_1_3_3_34_2 doi: 10.1104/pp.123.2.563 – ident: e_1_3_3_28_2 doi: 10.1111/tpj.12623 – ident: e_1_3_3_57_2 doi: 10.1093/sysbio/sys029 – ident: e_1_3_3_15_2 doi: 10.1038/msb.2011.39 – ident: e_1_3_3_11_2 doi: 10.7554/eLife.03031
SSID	ssj0009580
Score	2.5436983
Snippet	In plants, small groups of pluripotent stem cells called axillary meristems are required for the formation of the branches and flowers that eventually... Axillary meristems are groups of plant pluripotent stem cells responsible for the formation of secondary axes of growth, such as branches and flowers. A...
SourceID	unpaywall pubmedcentral proquest pubmed crossref pnas jstor
SourceType	Open Access Repository Aggregation Database Index Database Enrichment Source Publisher
StartPage	13372
SubjectTerms	Acetic acid Bayes Theorem Biological Sciences Cloning, Molecular Computational Biology Corn DNA Primers - genetics Electrophoretic Mobility Shift Assay Flowers - cytology Flowers - growth & development Gene Expression Regulation, Developmental - genetics Gene Expression Regulation, Developmental - physiology Gene Expression Regulation, Plant - genetics Gene Expression Regulation, Plant - physiology Genetics Hormones In Situ Hybridization Indoleacetic Acids - metabolism Meristem - growth & development Meristem - metabolism Models, Genetic Phylogeny Plant Proteins - genetics Plant Proteins - metabolism Plant reproduction Protein expression Real-Time Polymerase Chain Reaction Reproduction Signal transduction Signal Transduction - physiology Stem cells Zea mays Zea mays - growth & development
Title	Auxin signaling modules regulate maize inflorescence architecture
URI	https://www.jstor.org/stable/26465782 http://www.pnas.org/content/112/43/13372.abstract https://www.ncbi.nlm.nih.gov/pubmed/26464512 https://www.proquest.com/docview/1729126234 https://www.proquest.com/docview/1728256751 https://www.proquest.com/docview/1746881549 https://pubmed.ncbi.nlm.nih.gov/PMC4629326 https://www.pnas.org/content/pnas/112/43/13372.full.pdf
UnpaywallVersion	publishedVersion
Volume	112
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
journalDatabaseRights	– providerCode: PRVFSB databaseName: Free Full-Text Journals in Chemistry customDbUrl: eissn: 1091-6490 dateEnd: 20250402 omitProxy: true ssIdentifier: ssj0009580 issn: 0027-8424 databaseCode: HH5 dateStart: 19150101 isFulltext: true titleUrlDefault: http://abc-chemistry.org/ providerName: ABC ChemistRy – providerCode: PRVAFT databaseName: Open Access Digital Library customDbUrl: eissn: 1091-6490 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0009580 issn: 0027-8424 databaseCode: KQ8 dateStart: 19150101 isFulltext: true titleUrlDefault: http://grweb.coalliance.org/oadl/oadl.html providerName: Colorado Alliance of Research Libraries – providerCode: PRVAFT databaseName: Open Access Digital Library customDbUrl: eissn: 1091-6490 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0009580 issn: 0027-8424 databaseCode: KQ8 dateStart: 19150115 isFulltext: true titleUrlDefault: http://grweb.coalliance.org/oadl/oadl.html providerName: Colorado Alliance of Research Libraries – providerCode: PRVBFR databaseName: Free Medical Journals customDbUrl: eissn: 1091-6490 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0009580 issn: 0027-8424 databaseCode: DIK dateStart: 19150101 isFulltext: true titleUrlDefault: http://www.freemedicaljournals.com providerName: Flying Publisher – providerCode: PRVFQY databaseName: GFMER Free Medical Journals customDbUrl: eissn: 1091-6490 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0009580 issn: 0027-8424 databaseCode: GX1 dateStart: 0 isFulltext: true titleUrlDefault: http://www.gfmer.ch/Medical_journals/Free_medical.php providerName: Geneva Foundation for Medical Education and Research – providerCode: PRVAQN databaseName: PubMed Central customDbUrl: eissn: 1091-6490 dateEnd: 20250402 omitProxy: true ssIdentifier: ssj0009580 issn: 0027-8424 databaseCode: RPM dateStart: 19150101 isFulltext: true titleUrlDefault: https://www.ncbi.nlm.nih.gov/pmc/ providerName: National Library of Medicine
link	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3Pb9MwFH5i3QEuwIBBxjYFicN2SNrYjp0cK8SYkJg4UKmcIsd2RLUsrdpGwP76PTtuWBk_BNfkS-T4Pft99nv5DPCaKiUkw4GE0UdGLM2s5K0ikeJprqmRVGv7N_KHC34-Ye-n6dRvXax8WeWikSuXxLfV2jj1Du2FIRKDIaNDXFMJEtu96Xihqx3Y5TazNIDdycXH8eeuoAPnXdYdZ4vRMOIsH21EfQR1L4sxznEmaJKQrXjUlSRanVME_Ypz3i2dvN82C_n9q6zrW3Hp7BFMN1_UlaNcxu26jNX1T2KP__HJj-Gh56rhuHOuPbhnmiew52eDVXjiJatPn8J43H6bNaEtBpH2__bwaq7bGjHL7qh7E17J2bUJ0Z3r-dIpSCkT3k5iPIPJ2dtPb84jfzhDpFIu1jiLqoQZnmdUZqbMM4WNLEdEkkrnSEp0lcsKIaoiSnOk8abMpBREVoarzNa07sOgmTfmBYR5bkhVoUFGrGQZLmuRFRmNtF8YXgqjAog3JiqUVy63B2jUhcugC1rY3ip-2DSAk_6BRSfa8XvovrN5j0OCyK3EfwCBg_bPJ6RgtHC2COBw4xmFH_L4TlymJATZJAvgVX8bB6vNwMjGzFuHwRU5rtGSP2EY9pdVzgvgeedsW41jqW212HLDHmDFwrfvNLMvTjSccWKpegCnvcP-rW8O_gH7Eh4glXSitkQcwmC9bM0R0rV1eQw776bJsR-gN-11PC8
linkProvider	Unpaywall
linkToUnpaywall	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Nj9MwEB1B9wAXYIGFwIKCxGH3kLRxHDs5VojVCokVByqVU-TYjqjIplXbCNhfz4zjhi2fgmvyEjmesefZM3kGeJlqLRXHgYTRR0U8y0nyVrNIi6wwqVWpMfQ38tsLcT7jb-bZ3G9dbHxZ5apVG5fEp2ptnHrHdGGMxGDM0zGuqSSLaW86Xpn6JhwIyiyN4GB28W76oS_owHmX98fZYjSMBC8mO1EfmbqXxRjnBJdpkrC9eNSXJJLOKYJ-xTl_Lp281bUr9fWzapprcensLsx3X9SXo3yKu20V66sfxB7_45PvwR3PVcNp71yHcMO29-HQzwab8MRLVp8-gOm0-7JoQyoGUfR_e3i5NF2DmHV_1L0NL9Xiyobozs1y7RSktA2vJzEewuzs9ftX55E_nCHSmZBbnEV1wq0o8lTltipyjY2sJkyx2hRISkxdqBohumbaCKTxtsqVkkzVVuicalqPYNQuW_sYwqKwrK7RIBNe8RyXtciKrEHaL62opNUBxDsTldorl9MBGk3pMugyLam3yu82DeBkeGDVi3b8HnrkbD7gkCAKkvgPIHDQ4fmElTwtnS0CON55RumHPL4TlykJQzbJA3gx3MbBShkY1dpl5zC4Isc1WvInDMf-IuW8AB71zrbXOJ5Rq-WeGw4AEgvfv9MuPjrRcC4YUfUATgeH_VvfPPkH7FO4jVTSidoyeQyj7bqzz5Cubavnfmh-A4oUOz4
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Auxin+signaling+modules+regulate+maize+inflorescence+architecture&rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences+-+PNAS&rft.au=Mary+Galli&rft.au=Qiujie+Liu&rft.au=Britney+L.+Moss&rft.au=Simon+Malcomber&rft.date=2015-10-27&rft.pub=National+Acad+Sciences&rft.issn=0027-8424&rft.eissn=1091-6490&rft.volume=112&rft.issue=43&rft.spage=13372&rft_id=info:doi/10.1073%2Fpnas.1516473112&rft_id=info%3Apmid%2F26464512&rft.externalDBID=n%2Fa&rft.externalDocID=112_43_13372
thumbnail_m	http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=http%3A%2F%2Fwww.pnas.org%2Fcontent%2F112%2F43.cover.gif
thumbnail_s	http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=http%3A%2F%2Fwww.pnas.org%2Fcontent%2F112%2F43.cover.gif