IL-25/IL-33–responsive TH2 cells characterize nasal polyps with a default TH17 signature in nasal mucosa - Lam, Emily P.S.; Kariyawasam, Harsha H.; Rana, Batika M.J.; Durham, Stephen R.; McKenzie, Andrew N.J.; Powell, Nicholas; Orban, Nara; Lennartz-Walker, Melissa; Hopkins, Claire; Ying, Sun; Rimmer, Joanne; Lund, Valerie J.; et al. (Journal of allergy and clinical immunology, 2016)
Keywords: Cell culture; Chronic Disease; Chronic rhinosinusitis with nasal polyps; Cloning; Cytokines; Eosinophilia - immunology; Gene expression; Genotype & phenotype; Humans; IL-17RB; IL-25; IL-33; Interleukin-17 - immunology; Interleukin-33 - immunology; Lymphocytes; Mechanisms of Allergy and Clinical Immunology; microarray; nasal mucosa; Nasal Mucosa - immunology; Nasal Polyps - immunology; Rhinitis - immunology; Sinusitis - immunology; ST2; Studies; T cell receptors; T-cell phenotype; T-cell receptor Vβ repertoire; Th17 Cells - immunology; TH17 cells; TH2 cells; Th2 Cells - immunology; IL-17RB; IL-25; CRSwNP; T-cell phenotype; IL-33; T-cell receptor Vβ repertoire; ST2; ILC2; TH2 cells; microarray; AIM2; Chronic rhinosinusitis with nasal polyps; TCR Vβ; nasal mucosa; TH17 cells; CRTH2; CDR3; T(H)17 cells; T(H)2 cells