Oesophagogastric junction adenocarcinoma: which therapeutic approach?
Gastric and oesophageal cancers are among the leading causes of cancer-related death worldwide. By contrast with the decreasing prevalence of gastric cancer, incidence and prevalence of oesophagogastric junction adenocarcinoma (OGJA) are rising rapidly in developed countries. We provide an update ab...
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| Published in | The lancet oncology Vol. 12; no. 3; pp. 296 - 305 |
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| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
Elsevier Ltd
01.03.2011
Elsevier Limited |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1470-2045 1474-5488 1474-5488 |
| DOI | 10.1016/S1470-2045(10)70125-X |
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| Abstract | Gastric and oesophageal cancers are among the leading causes of cancer-related death worldwide. By contrast with the decreasing prevalence of gastric cancer, incidence and prevalence of oesophagogastric junction adenocarcinoma (OGJA) are rising rapidly in developed countries. We provide an update about treatment strategies for resectable OGJA. Here we review findings from the latest randomised trials and meta-analyses, and propose guidelines regarding endoscopic, surgical, and perioperative treatments. Through a team approach, members from all diagnostic and therapeutic disciplines, such as gastroenterologists, surgeons, oncologists, radiologists, and radiotherapists, can effectively administer a range of treatment modalities. |
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| AbstractList | Gastric and oesophageal cancers are among the leading causes of cancer-related death worldwide. By contrast with the decreasing prevalence of gastric cancer, incidence and prevalence of oesophagogastric junction adenocarcinoma (OGJA) are rising rapidly in developed countries. We provide an update about treatment strategies for resectable OGJA. Here we review findings from the latest randomised trials and meta-analyses, and propose guidelines regarding endoscopic, surgical, and perioperative treatments. Through a team approach, members from all diagnostic and therapeutic disciplines, such as gastroenterologists, surgeons, oncologists, radiologists, and radiotherapists, can effectively administer a range of treatment modalities. Gastric and oesophageal cancers are among the leading causes of cancer-related death worldwide. By contrast with the decreasing prevalence of gastric cancer, incidence and prevalence of oesophagogastric junction adenocarcinoma (OGJA) are rising rapidly in developed countries. We provide an update about treatment strategies for resectable OGJA. Here we review findings from the latest randomised trials and meta-analyses, and propose guidelines regarding endoscopic, surgical, and perioperative treatments. Through a team approach, members from all diagnostic and therapeutic disciplines, such as gastroenterologists, surgeons, oncologists, radiologists, and radiotherapists, can effectively administer a range of treatment modalities.Gastric and oesophageal cancers are among the leading causes of cancer-related death worldwide. By contrast with the decreasing prevalence of gastric cancer, incidence and prevalence of oesophagogastric junction adenocarcinoma (OGJA) are rising rapidly in developed countries. We provide an update about treatment strategies for resectable OGJA. Here we review findings from the latest randomised trials and meta-analyses, and propose guidelines regarding endoscopic, surgical, and perioperative treatments. Through a team approach, members from all diagnostic and therapeutic disciplines, such as gastroenterologists, surgeons, oncologists, radiologists, and radiotherapists, can effectively administer a range of treatment modalities. Summary Gastric and oesophageal cancers are among the leading causes of cancer-related death worldwide. By contrast with the decreasing prevalence of gastric cancer, incidence and prevalence of oesophagogastric junction adenocarcinoma (OGJA) are rising rapidly in developed countries. We provide an update about treatment strategies for resectable OGJA. Here we review findings from the latest randomised trials and meta-analyses, and propose guidelines regarding endoscopic, surgical, and perioperative treatments. Through a team approach, members from all diagnostic and therapeutic disciplines, such as gastroenterologists, surgeons, oncologists, radiologists, and radiotherapists, can effectively administer a range of treatment modalities. |
| Author | Triboulet, Jean Pierre Piessen, Guillaume Gronnier, Caroline Briez, Nicolas Mariette, Christophe |
| Author_xml | – sequence: 1 givenname: Christophe surname: Mariette fullname: Mariette, Christophe email: c-mariette@chru-lille.fr organization: Department of Digestive and Oncological Surgery, University Hospital C Huriez, Lille, France – sequence: 2 givenname: Guillaume surname: Piessen fullname: Piessen, Guillaume organization: Department of Digestive and Oncological Surgery, University Hospital C Huriez, Lille, France – sequence: 3 givenname: Nicolas surname: Briez fullname: Briez, Nicolas organization: Department of Digestive and Oncological Surgery, University Hospital C Huriez, Lille, France – sequence: 4 givenname: Caroline surname: Gronnier fullname: Gronnier, Caroline organization: Department of Digestive and Oncological Surgery, University Hospital C Huriez, Lille, France – sequence: 5 givenname: Jean Pierre surname: Triboulet fullname: Triboulet, Jean Pierre organization: Department of Digestive and Oncological Surgery, University Hospital C Huriez, Lille, France |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/21109491$$D View this record in MEDLINE/PubMed |
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| Snippet | Gastric and oesophageal cancers are among the leading causes of cancer-related death worldwide. By contrast with the decreasing prevalence of gastric cancer,... Summary Gastric and oesophageal cancers are among the leading causes of cancer-related death worldwide. By contrast with the decreasing prevalence of gastric... |
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| SubjectTerms | Ablation Adenocarcinoma - pathology Adenocarcinoma - surgery Adenocarcinoma - therapy Antineoplastic Agents - therapeutic use Cancer therapies Combined Modality Therapy Dissection Endoscopy Esophageal cancer Esophageal Neoplasms - pathology Esophageal Neoplasms - surgery Esophageal Neoplasms - therapy Esophagogastric Junction - pathology Gastric cancer Hematology, Oncology and Palliative Medicine Humans Industrialized nations Medical prognosis Mortality Ostomy Patients Stomach Neoplasms - pathology Stomach Neoplasms - surgery Stomach Neoplasms - therapy Surgery Tumors |
| Title | Oesophagogastric junction adenocarcinoma: which therapeutic approach? |
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