Noninvasive method for assessing the human circadian clock using hair follicle cells - Akashi, Makoto; Soma, Haruhiko; Yamamoto, Takuro; Tsugitomi, Asuka; Yamashita, Shiko; Yamamoto, Takuya; Nishida, Eisuke; Yasuda, Akio; Liao, James K.; Node, Koichi; Takahashi, Joseph S. (Proceedings of the National Academy of Sciences - PNAS, 2010)
Keywords: Algorithms; Animals; Biological Clocks - physiology; Biological Sciences; Biopsy; Cells; Circadian rhythm; Circadian Rhythm - physiology; Circadian rhythms; CLOCK Proteins - genetics; Cosine function; Female; Gene expression; Gene Expression Profiling - instrumentation; Gene Expression Profiling - methods; Hair; Hair cells; Hair Follicle - cytology; Hair Follicle - metabolism; Hair follicles; head; Humans; Instructional materials; Lifestyle; Male; Mice; Models, Genetic; Nuclear Receptor Subfamily 1, Group D, Member 1 - genetics; Oligonucleotide Array Sequence Analysis; Period Circadian Proteins - genetics; Receptors, Cytoplasmic and Nuclear - genetics; Repressor Proteins - genetics; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; RNA; Rotating shifts; Scalp