Upward trend in follicular lymphoma among the Korean population: 10-year experience at a large tertiary institution
Background: Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma (NHL) in Western countries. However, it is relatively rare in Asia. This study examined epidemiologic characteristics of FL in South Korea, with an emphasis on recent trends of increase in cases. Methods: We retrospe...
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| Published in | Journal of pathology and translational medicine Vol. 55; no. 5; pp. 330 - 337 |
|---|---|
| Main Authors | , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Seoul
Korean Society of Pathologists, Korean Society for Cytopathology
01.09.2021
The Korean Society of Pathologists and the Korean Society for Cytopathology Korean Society of Pathologists & the Korean Society for Cytopathology 대한병리학회 |
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| Online Access | Get full text |
| ISSN | 2383-7837 2383-7845 2383-7845 |
| DOI | 10.4132/jptm.2021.07.25 |
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| Abstract | Background: Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma (NHL) in Western countries. However, it is relatively rare in Asia. This study examined epidemiologic characteristics of FL in South Korea, with an emphasis on recent trends of increase in cases. Methods: We retrospectively examined 239 cases of newly diagnosed FL at a large tertiary institution in Korea (Asan Medical Center, Seoul, Republic of Korea) between 2008 and 2017. Age-adjusted incidence rates and clinicopathological variables were analyzed, and joinpoint regression analysis was used to identify the changes. Results: The age-adjusted incidence of FL significantly increased during the study period (p = .034), and the ratio of (relative incidence) patients with FL to patients with NHL increased from 4.28% to 9.35% in the same period. Over the 10-year study assessment duration, the proportion of patients with stage III/IV FL (p = .035) and expression of BCL2 (p = .022) or BCL6 (p = .039) significantly increased. From 2013–2017, the proportion of patients with highrisk Follicular Lymphoma International Prognostic Index (FLIPI) score increased (21.5% to 28.7%), whereas that of low-risk FLIPI decreased (55.4% to 38.6%), although those results were not statistically significant (p = .066). Conclusions: We found an increasing incidence of FL, with a disproportionate increase in the incidence of high-stage disease and recent changes in the clinicopathologic features of the Korean patient population. |
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| AbstractList | Background: Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma (NHL) in Western countries. However, it is relatively rare in Asia. This study examined epidemiologic characteristics of FL in South Korea, with an emphasis on recent trends of increase in cases. Methods: We retrospectively examined 239 cases of newly diagnosed FL at a large tertiary institution in Korea (Asan Medical Center, Seoul, Republic of Korea) between 2008 and 2017. Age-adjusted incidence rates and clinicopathological variables were analyzed, and joinpoint regression analysis was used to identify the changes. Results: The age-adjusted incidence of FL significantly increased during the study period (p = .034), and the ratio of (relative incidence) patients with FL to patients with NHL increased from 4.28% to 9.35% in the same period. Over the 10-year study assessment duration, the proportion of patients with stage III/IV FL (p = .035) and expression of BCL2 (p=.022) or BCL6 (p=.039) significantly increased. From 2013-2017, the proportion of patients with high-risk Follicular Lymphoma International Prognostic Index (FLIPI) score increased (21.5% to 28.7%), whereas that of low-risk FLIPI decreased (55.4% to 38.6%), although those results were not statistically significant (p = .066). Conclusions: We found an increasing incidence of FL, with a disproportionate increase in the incidence of high-stage disease and recent changes in the clinicopathologic features of the Korean patient population. Background Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma (NHL) in Western countries. However, it is relatively rare in Asia. This study examined epidemiologic characteristics of FL in South Korea, with an emphasis on recent trends of increase in cases. Methods We retrospectively examined 239 cases of newly diagnosed FL at a large tertiary institution in Korea (Asan Medical Center, Seoul, Republic of Korea) between 2008 and 2017. Age-adjusted incidence rates and clinicopathological variables were analyzed, and joinpoint regression analysis was used to identify the changes. Results The age-adjusted incidence of FL significantly increased during the study period (p = .034), and the ratio of (relative incidence) patients with FL to patients with NHL increased from 4.28% to 9.35% in the same period. Over the 10-year study assessment duration, the proportion of patients with stage III/IV FL (p = .035) and expression of BCL2 (p = .022) or BCL6 (p = .039) significantly increased. From 2013–2017, the proportion of patients with highrisk Follicular Lymphoma International Prognostic Index (FLIPI) score increased (21.5% to 28.7%), whereas that of low-risk FLIPI decreased (55.4% to 38.6%), although those results were not statistically significant (p = .066). Conclusions We found an increasing incidence of FL, with a disproportionate increase in the incidence of high-stage disease and recent changes in the clinicopathologic features of the Korean patient population. Background: Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma (NHL) in Western countries. However, it is relatively rare in Asia. This study examined epidemiologic characteristics of FL in South Korea, with an emphasis on recent trends of increase in cases. Methods: We retrospectively examined 239 cases of newly diagnosed FL at a large tertiary institution in Korea (Asan Medical Center, Seoul, Republic of Korea) between 2008 and 2017. Age-adjusted incidence rates and clinicopathological variables were analyzed, and joinpoint regression analysis was used to identify the changes. Results: The age-adjusted incidence of FL significantly increased during the study period (p = .034), and the ratio of (relative incidence) patients with FL to patients with NHL increased from 4.28% to 9.35% in the same period. Over the 10-year study assessment duration, the proportion of patients with stage III/IV FL (p = .035) and expression of BCL2 (p = .022) or BCL6 (p = .039) significantly increased. From 2013–2017, the proportion of patients with highrisk Follicular Lymphoma International Prognostic Index (FLIPI) score increased (21.5% to 28.7%), whereas that of low-risk FLIPI decreased (55.4% to 38.6%), although those results were not statistically significant (p = .066). Conclusions: We found an increasing incidence of FL, with a disproportionate increase in the incidence of high-stage disease and recent changes in the clinicopathologic features of the Korean patient population. KCI Citation Count: 0 Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma (NHL) in Western countries. However, it is relatively rare in Asia. This study examined epidemiologic characteristics of FL in South Korea, with an emphasis on recent trends of increase in cases.BACKGROUNDFollicular lymphoma (FL) is the second most common non-Hodgkin lymphoma (NHL) in Western countries. However, it is relatively rare in Asia. This study examined epidemiologic characteristics of FL in South Korea, with an emphasis on recent trends of increase in cases.We retrospectively examined 239 cases of newly diagnosed FL at a large tertiary institution in Korea (Asan Medical Center, Seoul, Republic of Korea) between 2008 and 2017. Age-adjusted incidence rates and clinicopathological variables were analyzed, and joinpoint regression analysis was used to identify the changes.METHODSWe retrospectively examined 239 cases of newly diagnosed FL at a large tertiary institution in Korea (Asan Medical Center, Seoul, Republic of Korea) between 2008 and 2017. Age-adjusted incidence rates and clinicopathological variables were analyzed, and joinpoint regression analysis was used to identify the changes.The age-adjusted incidence of FL significantly increased during the study period (p = .034), and the ratio of (relative incidence) patients with FL to patients with NHL increased from 4.28% to 9.35% in the same period. Over the 10-year study assessment duration, the proportion of patients with stage III/IV FL (p = .035) and expression of BCL2 (p = .022) or BCL6 (p = .039) significantly increased. From 2013-2017, the proportion of patients with highrisk Follicular Lymphoma International Prognostic Index (FLIPI) score increased (21.5% to 28.7%), whereas that of low-risk FLIPI decreased (55.4% to 38.6%), although those results were not statistically significant (p = .066).RESULTSThe age-adjusted incidence of FL significantly increased during the study period (p = .034), and the ratio of (relative incidence) patients with FL to patients with NHL increased from 4.28% to 9.35% in the same period. Over the 10-year study assessment duration, the proportion of patients with stage III/IV FL (p = .035) and expression of BCL2 (p = .022) or BCL6 (p = .039) significantly increased. From 2013-2017, the proportion of patients with highrisk Follicular Lymphoma International Prognostic Index (FLIPI) score increased (21.5% to 28.7%), whereas that of low-risk FLIPI decreased (55.4% to 38.6%), although those results were not statistically significant (p = .066).We found an increasing incidence of FL, with a disproportionate increase in the incidence of high-stage disease and recent changes in the clinicopathologic features of the Korean patient population.CONCLUSIONSWe found an increasing incidence of FL, with a disproportionate increase in the incidence of high-stage disease and recent changes in the clinicopathologic features of the Korean patient population. |
| Author | Yoon, Dok Hyun Cho, Hyungwoo Go, Heounjeong Suh, Cheolwon Kim, Meejeong Huh, Jooryung Hwang, Hee Sang Park, Chan Sik |
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| CitedBy_id | crossref_primary_10_3904_kjm_2023_98_5_231 crossref_primary_10_12701_jyms_2023_00584 crossref_primary_10_22246_jikm_2023_44_3_585 crossref_primary_10_3390_jcm12041417 crossref_primary_10_1111_his_14617 |
| Cites_doi | 10.1016/j.athoracsur.2019.08.018 10.1007/s12185-018-2403-9 10.1016/j.clml.2015.12.012 10.1309/ajcptma1f6lwytqv 10.1200/jco.2008.18.1495 10.1002/(sici)1097-0258(20000215)19 10.1002/ajh.21824 10.5858/arpa.2018-0217-ra 10.1309/tnkl7gdc66r9wpv5 10.1111/pin.12733 10.3960/jslrt.54.3 10.1182/blood-2006-09-045989 10.1002/ajh.24937 10.1038/s41408-020-0299-0 10.3324/haematol.10384 10.1016/j.clml.2017.07.002 10.1038/modpathol.2017.134 10.1093/annonc/mdp502 10.1002/hon.2392 10.1182/blood.v85.12.3671.bloodjournal85123671 10.1182/blood-2003-05-1545 10.1038/sj.leu.2403738 10.3324/haematol.2009.007203 10.1016/j.canep.2011.03.002 10.4143/crt.2020.089 10.3109/10428191003743460 10.3747/co.26.4625 10.4143/crt.2017.093 10.1517/17530059.2012.686996 10.1016/s2352-3026(18)30090-5 10.1182/blood.v99.12.4265 |
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| References | ref13 ref35 Swerdlow (ref2) 2017 ref12 ref15 ref37 ref14 ref31 ref30 ref11 ref33 ref10 ref32 (ref3) 2013 ref1 ref17 ref16 ref38 ref18 Bai (ref8) 2015 Kawaguchi (ref19) 2018 ref24 ref23 ref26 ref25 ref22 ref21 ref28 ref27 ref29 Szczuraszek (ref20) 2008 ref7 Schraders (ref34) 2005 ref9 ref4 ref6 ref5 Wang (ref36) 2005 |
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| Snippet | Background: Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma (NHL) in Western countries. However, it is relatively rare in Asia. This... Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma (NHL) in Western countries. However, it is relatively rare in Asia. This study examined... Background Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma (NHL) in Western countries. However, it is relatively rare in Asia. This... |
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| SubjectTerms | Age bcl2 bcl6 Cloning follicular lymphoma follicular lymphoma international prognostic index (flipi) korea Lymphoma Original Patients Regression analysis Software Trends 병리학 |
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| Title | Upward trend in follicular lymphoma among the Korean population: 10-year experience at a large tertiary institution |
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| ispartofPNX | Journal of Pathology and Translational Medicine, 2021, 55(5), , pp.330-337 |
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