Genetic Markers of Toxicity From Capecitabine and Other Fluorouracil-Based Regimens: Investigation in the QUASAR2 Study, Systematic Review, and Meta-Analysis - Rosmarin, Dan; Palles, Claire; Church, David; Domingo, Enric; Jones, Angela; Johnstone, Elaine; Wang, Haitao; Love, Sharon; Julier, Patrick; Scudder, Claire; Nicholson, George; Gonzalez-Neira, Anna; et al. (Journal of clinical oncology, 2014)
Keywords: Antineoplastic Combined Chemotherapy Protocols - adverse effects; Biological and medical sciences; Capecitabine; Colorectal Neoplasms - drug therapy; Deoxycytidine - administration & dosage; Deoxycytidine - adverse effects; Deoxycytidine - analogs & derivatives; Dihydrouracil Dehydrogenase (NADP) - genetics; Drug-Related Side Effects and Adverse Reactions - genetics; Fluorouracil - administration & dosage; Fluorouracil - adverse effects; Fluorouracil - analogs & derivatives; Genetic Markers; Humans; Life Sciences; Medical sciences; ORIGINAL REPORTS; Polymorphism, Genetic; Predictive Value of Tests; Thymidylate Synthase - genetics; Tumors; Antineoplastic agent; Genetic marker; Enzyme; Capecitabine; Toxicity; Fluoropyrimidine derivatives; Transferases; Evidence-based practice; Enzyme inhibitor; Systematic review; Prodrug; Thymidylate synthase; Evidence-based medicine; Metaanalysis; Cancerology; Antimetabolic; Methyltransferases; Pyrimidine derivatives; Therapeutic protocol; Pyrimidine nucleoside; Fluorouracil