Nitration of soluble proteins in organotypic culture models of Parkinson's disease - Larsen, Trine R.; Söderling, Ann-Sofi; Caidahl, Kenneth; Roepstorff, Peter; Gramsbergen, Jan Bert (Neurochemistry international, 2008)
Keywords: 1-Methyl-4-phenylpyridinium; 1-Methyl-4-phenylpyridinium - pharmacology; 3-Nitrotyrosine; alpha-synuclein; Animals; Biological and medical sciences; Cell Survival - drug effects; Cell Survival - physiology; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Dopamine; Dopamine - metabolism; dopaminergic-neurons; Dose-Response Relationship, Drug; Enzyme Inhibitors - pharmacology; free 3-nitrotyrosine; Fundamental and applied biological sciences. Psychology; induced neurotoxicity; Mass spectrometry; Medical sciences; Mice; Mice, Inbred C57BL; Molecular Biology; Molekylärbiologi; Neurochemistry - methods; Neurology; neuronal nitric-oxide; Neurosciences; Neurotoxins - pharmacology; Neurovetenskaper; Nitric oxide; Nitric Oxide Donors - pharmacology; Nitric Oxide Synthase - antagonists & inhibitors; Nitric Oxide Synthase - metabolism; Nitro Compounds - metabolism; Organ Culture Techniques; oxidative stress; Oxidative Stress - physiology; Parkinson Disease - metabolism; Parkinson Disease - physiopathology; prevents nitration; Proteins - metabolism; Pterins - pharmacology; Reactive Nitrogen Species - metabolism; Rotenone; Substantia Nigra - metabolism; Substantia Nigra - physiopathology; tetrahydrobiopterin precursor sepiapterin; Tyrosine - analogs & derivatives; Tyrosine - analysis; Tyrosine - metabolism; Tyrosine 3-Monooxygenase - metabolism; tyrosine-hydroxylase; Uncoupling Agents - pharmacology; Vertebrates: nervous system and sense organs; O 2; NO; Dopamine; l-NAME; MPP; AMPT; SIN-1; Rotenone; LDH; NOS; PD; TH; SNOG; Nitric oxide; 3-NT; 1-Methyl-4-phenylpyridinium; ONOO; 3-Nitrotyrosine; HBSS; MPTP; DOPA; DA; Mass spectrometry; Nitration; Nervous system diseases; Organotypic culture; Parkinson disease; Catecholamine; Protein; Cerebral disorder; Central nervous system disease; Neurotransmitter; Degenerative disease; Models; Extrapyramidal syndrome