菲律宾蛤仔对镉、铜暴露的蓄积作用及其抗氧化酶系统的响应研究
研究了镉（Cd）、铜（Cu）2种重金属单一暴露下菲律宾蛤仔（Ruditapes philippinarum）肝胰腺和鳃组织内的重金属富集特征和抗氧化酶活力变化特点。结果表明，蛤仔肝胰腺与鳃对Cd、Cu的富集量随重金属浓度与暴靠时间的增加而增火，具有明显的浓度效应与时间效应；菲律宾蛤仔对Cd的富集能力高于Cu，H．肝胰腺中审盖属的蓄积量高于鳃；蛤仔肝胰腺和鳃组织中超氧化物歧化酶（SOD）、谷胱廿肽过氧化物酶（（；Px）和谷胱竹肽硫转移酶（CST）活力在暴露的某些时段被显著诱导（P〈0．05），似随暴露时问延长或重金属浓度增加，SODf11GST活力则被显著抑制（P〈O．05），而CPx活力随暴露...
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| Published in | 南方水产科学 Vol. 9; no. 5; pp. 64 - 70 |
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| Main Author | |
| Format | Journal Article |
| Language | Chinese |
| Published |
中国水产科学研究院南海水产研究所,农业部南海渔业资源开发利用重点实验室,广东省渔业生态环境重点实验室,广东广州510300%中国科学院烟台海岸带研究所,海岸带环境过程重点实验室,山东烟台264003
2013
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| Subjects | |
| Online Access | Get full text |
| ISSN | 2095-0780 |
| DOI | 10.3969/j.issn.2095-0780.2013.05.011 |
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| Abstract | 研究了镉（Cd）、铜（Cu）2种重金属单一暴露下菲律宾蛤仔（Ruditapes philippinarum）肝胰腺和鳃组织内的重金属富集特征和抗氧化酶活力变化特点。结果表明，蛤仔肝胰腺与鳃对Cd、Cu的富集量随重金属浓度与暴靠时间的增加而增火，具有明显的浓度效应与时间效应；菲律宾蛤仔对Cd的富集能力高于Cu，H．肝胰腺中审盖属的蓄积量高于鳃；蛤仔肝胰腺和鳃组织中超氧化物歧化酶（SOD）、谷胱廿肽过氧化物酶（（；Px）和谷胱竹肽硫转移酶（CST）活力在暴露的某些时段被显著诱导（P〈0．05），似随暴露时问延长或重金属浓度增加，SODf11GST活力则被显著抑制（P〈O．05），而CPx活力随暴露时问延K逐渐恢复至对照组水平、菲律宾蛤仔肝胰腺和鳃2种组织中SOD和GST的活性变化可作为海洋Cu^2＋Cd^2＋钙染的牛物标志物． |
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| AbstractList | 研究了镉（Cd）、铜（Cu）2种重金属单一暴露下菲律宾蛤仔（Ruditapes philippinarum）肝胰腺和鳃组织内的重金属富集特征和抗氧化酶活力变化特点。结果表明，蛤仔肝胰腺与鳃对Cd、Cu的富集量随重金属浓度与暴靠时间的增加而增火，具有明显的浓度效应与时间效应；菲律宾蛤仔对Cd的富集能力高于Cu，H．肝胰腺中审盖属的蓄积量高于鳃；蛤仔肝胰腺和鳃组织中超氧化物歧化酶（SOD）、谷胱廿肽过氧化物酶（（；Px）和谷胱竹肽硫转移酶（CST）活力在暴露的某些时段被显著诱导（P〈0．05），似随暴露时问延长或重金属浓度增加，SODf11GST活力则被显著抑制（P〈O．05），而CPx活力随暴露时问延K逐渐恢复至对照组水平、菲律宾蛤仔肝胰腺和鳃2种组织中SOD和GST的活性变化可作为海洋Cu^2＋Cd^2＋钙染的牛物标志物． X55%S949; 研究了镉(Cd)、铜(Cu)2种重金属单一暴露下菲律宾蛤仔(Ruditapes philippinarum)肝胰腺和鳃组织内的重金属富集特征和抗氧化酶活力变化特点.结果表明,蛤仔肝胰腺与鳃对Cd、Cu的富集量随重金属浓度与暴露时间的增加而增大,具有明显的浓度效应与时间效应;菲律宾蛤仔对Cd的富集能力高于Cu,且肝胰腺中重金属的蓄积量高于鳃;蛤仔肝胰腺和鳃组织中超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GPx)和谷胱甘肽硫转移酶(GST)活力在暴露的某些时段被显著诱导(P＜0.05),但随暴露时间延长或重金属浓度增加,SOD和GST活力则被显著抑制(P＜0.05),而GPx活力随暴露时间延长逐渐恢复至对照组水平.菲律宾蛤仔肝胰腺和鳃2种组织中SOD和GST的活性变化可作为海洋Cu2、Cd2+污染的生物标志物. |
| Author | 张林宝 吴惠丰 孙伟 蔡文贵 贾晓平 |
| AuthorAffiliation | 中国水产科学研究院南海水产研究所,农业部南海渔业资源开发利用重点实验室,广东省渔业生态环境晕点实验卒,广东广州510300 中国科学院烟台海岸带研究所,海岸带环境过程重点实验室,山东烟台264003 |
| AuthorAffiliation_xml | – name: 中国水产科学研究院南海水产研究所,农业部南海渔业资源开发利用重点实验室,广东省渔业生态环境重点实验室,广东广州510300%中国科学院烟台海岸带研究所,海岸带环境过程重点实验室,山东烟台264003 |
| Author_FL | WU Huifeng CAI Weigui SUN Wei ZHANG Linbao JIA Xiaoping |
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| ContentType | Journal Article |
| Copyright | Copyright © Wanfang Data Co. Ltd. All Rights Reserved. |
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| DOI | 10.3969/j.issn.2095-0780.2013.05.011 |
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| DocumentTitleAlternate | Bioaccumulation and antioxidant responses in Manila clam （Ruditapes philippinarum） under cadmium and copper exposure |
| DocumentTitle_FL | Bioaccumulation and antioxidant responses in Manila clam (Ruditapes philippinarum) under cadmium and copper exposure |
| EndPage | 70 |
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| Keywords | Cd2 Cu2 抗氧化酶 copper ion 菲律宾蛤仔 Ruditapes philippinarum cadmium ion bioaccumulation antioxidant enzymes 生物蓄积 |
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| Notes | We studied the bioaccumulation characteristics and antioxidant enzymes activity changes of Manila clam, Ruditapes philip- pinarum under the exposure to cadmium （Cd） and copper （Cu）. The bioconcentrations of Cd and Cu in gill and hepatopancreas of R. philippinarum showed obvious time and dose dependent responses. The clam showed higher bioaccumulation ability on Cd than that of Cu, and the heavy metal concentrations in hepatopancreas were greater than those in gill. Additionally, the acfivilies of superoxide dismutase （SOD）, glutathione peroxidases （GPx） and glutathione stransferases （GST） were significantly promoted in hepatopancreas and gill of R. philippinarum at difl＇erent concentrations and time intervals （ P 〈 0. 05 ） , while the activities of SOD and GST were sig- nificantly inhibited at high concentrations of Cd and Cu （P 〈 0. 05）. The activities of GPx recovered to the original level with the time progressed. Taken together, the changes of SOD and GST activities in hepatopancreas and gills of R. phili |
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| PublicationTitle | 南方水产科学 |
| PublicationTitleAlternate | South China Fisheries Science |
| PublicationTitle_FL | South China Fisheries Science |
| PublicationYear | 2013 |
| Publisher | 中国水产科学研究院南海水产研究所,农业部南海渔业资源开发利用重点实验室,广东省渔业生态环境重点实验室,广东广州510300%中国科学院烟台海岸带研究所,海岸带环境过程重点实验室,山东烟台264003 |
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| Snippet | 研究了镉（Cd）、铜（Cu）2种重金属单一暴露下菲律宾蛤仔（Ruditapes philippinarum）肝胰腺和鳃组织内的重金属富集特征和抗氧化酶活力变化特点。结果表明，蛤仔肝胰腺与鳃... X55%S949; 研究了镉(Cd)、铜(Cu)2种重金属单一暴露下菲律宾蛤仔(Ruditapes philippinarum)肝胰腺和鳃组织内的重金属富集特征和抗氧化酶活力变化特点.结果表明,蛤仔肝胰腺与... |
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| SubjectTerms | Cd^2 Cu^2 抗氧化酶 牛物蓄积 菲律宾蛤仔 |
| Title | 菲律宾蛤仔对镉、铜暴露的蓄积作用及其抗氧化酶系统的响应研究 |
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