Estimated Incubation Period and Serial Interval for Human-to-Human Influenza A(H7N9) Virus Transmission

We estimated the incubation period and serial interval for human-to-human-transmitted avian influenza A(H7N9) virus infection using case-patient clusters from epidemics in China during 2013-2017. The median incubation period was 4 days and serial interval 9 days. China's 10-day monitoring perio...

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Published inEmerging infectious diseases Vol. 25; no. 10; pp. 1982 - 1983
Main Authors Zhou, Lei, Li, Qun, Uyeki, Timothy M.
Format Journal Article
LanguageEnglish
Published United States U.S. National Center for Infectious Diseases 01.10.2019
Centers for Disease Control and Prevention
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ISSN1080-6040
1080-6059
1080-6059
DOI10.3201/eid2510.190117

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Abstract We estimated the incubation period and serial interval for human-to-human-transmitted avian influenza A(H7N9) virus infection using case-patient clusters from epidemics in China during 2013-2017. The median incubation period was 4 days and serial interval 9 days. China's 10-day monitoring period for close contacts of case-patients should detect most secondary infections.
AbstractList We estimated the incubation period and serial interval for human-to-human-transmitted avian influenza A(H7N9) virus infection using case-patient clusters from epidemics in China during 2013-2017. The median incubation period was 4 days and serial interval 9 days. China's 10-day monitoring period for close contacts of case-patients should detect most secondary infections.
We estimated the incubation period and serial interval for human-to-human-transmitted avian influenza A(H7N9) virus infection using case-patient clusters from epidemics in China during 2013-2017. The median incubation period was 4 days and serial interval 9 days. China's 10-day monitoring period for close contacts of case-patients should detect most secondary infections.We estimated the incubation period and serial interval for human-to-human-transmitted avian influenza A(H7N9) virus infection using case-patient clusters from epidemics in China during 2013-2017. The median incubation period was 4 days and serial interval 9 days. China's 10-day monitoring period for close contacts of case-patients should detect most secondary infections.
Audience Professional
Academic
Author Uyeki, Timothy M.
Zhou, Lei
Li, Qun
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Cites_doi 10.1016/S1473-3099(09)70069-6
10.3201/eid1411.080509
10.1093/aje/kwv115
10.3201/eid2402.171565
10.1016/S0140-6736(13)61171-X
10.1371/journal.pone.0148506
10.1056/NEJMoa1304617
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Keywords influenza
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incubation period
serial interval
zoonoses
H7N9
human-to-human transmission
respiratory infections
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References Li (key-10.3201/eid2510.190117-201909170803-R1) 2014; 370
Cowling (key-10.3201/eid2510.190117-201909170803-R4) 2013; 382
key-10.3201/eid2510.190117-201909170803-R2
Lessler (key-10.3201/eid2510.190117-201909170803-R8) 2009; 9
Zhou (key-10.3201/eid2510.190117-201909170803-R3) 2018; 24
Huai (key-10.3201/eid2510.190117-201909170803-R7) 2008; 14
Virlogeux (key-10.3201/eid2510.190117-201909170803-R5) 2015; 182
Virlogeux (key-10.3201/eid2510.190117-201909170803-R6) 2016; 11
References_xml – volume: 9
  start-page: 291
  year: 2009
  ident: key-10.3201/eid2510.190117-201909170803-R8
  article-title: Incubation periods of acute respiratory viral infections: a systematic review.
  publication-title: Lancet Infect Dis
  doi: 10.1016/S1473-3099(09)70069-6
– volume: 14
  start-page: 1819
  year: 2008
  ident: key-10.3201/eid2510.190117-201909170803-R7
  article-title: Incubation period for human cases of avian influenza A (H5N1) infection, China.
  publication-title: Emerg Infect Dis
  doi: 10.3201/eid1411.080509
– volume: 182
  start-page: 723
  year: 2015
  ident: key-10.3201/eid2510.190117-201909170803-R5
  article-title: Estimating the distribution of the incubation periods of human avian influenza A(H7N9) virus infections.
  publication-title: Am J Epidemiol
  doi: 10.1093/aje/kwv115
– volume: 24
  start-page: 397
  year: 2018
  ident: key-10.3201/eid2510.190117-201909170803-R3
  article-title: Clusters of human infection and human-to-human transmission of avian influenza A(H7N9) virus, 2013–2017.
  publication-title: Emerg Infect Dis
  doi: 10.3201/eid2402.171565
– volume: 382
  start-page: 129
  year: 2013
  ident: key-10.3201/eid2510.190117-201909170803-R4
  article-title: Comparative epidemiology of human infections with avian influenza A H7N9 and H5N1 viruses in China: a population-based study of laboratory-confirmed cases.
  publication-title: Lancet
  doi: 10.1016/S0140-6736(13)61171-X
– volume: 11
  start-page: e0148506
  year: 2016
  ident: key-10.3201/eid2510.190117-201909170803-R6
  article-title: Association between the severity of influenza A(H7N9) virus infections and length of the incubation period.
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0148506
– ident: key-10.3201/eid2510.190117-201909170803-R2
– volume: 370
  start-page: 520
  year: 2014
  ident: key-10.3201/eid2510.190117-201909170803-R1
  article-title: Epidemiology of human infections with avian influenza A(H7N9) virus in China.
  publication-title: N Engl J Med
  doi: 10.1056/NEJMoa1304617
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Snippet We estimated the incubation period and serial interval for human-to-human-transmitted avian influenza A(H7N9) virus infection using case-patient clusters from...
We estimated the incubation period and serial interval for human-to-human–transmitted avian influenza A(H7N9) virus infection using case-patient clusters from...
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StartPage 1982
SubjectTerms Avian influenza
China
Chinese history
Disease transmission
Epidemics
H7N9
Health aspects
human-to-human transmission
incubation period
Infection
Influenza
Medical research
Research Letter
serial interval
viruses
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