Patient-rated scales improve the classification accuracy for patients with depression and anxiety disorder: a linear discriminant analysis

Background The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in distinguishing patients with affective and anxiety disorders from healthy controls (HCs). Methods We recruited a total of 122 subjects, compri...

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Published inBMC psychiatry Vol. 24; no. 1; pp. 785 - 10
Main Authors Ji, Shanling, Zhang, Jing, Zhou, Cong, Chen, Min, Yu, Hao
Format Journal Article
LanguageEnglish
Published London BioMed Central 11.11.2024
BioMed Central Ltd
BMC
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ISSN1471-244X
1471-244X
DOI10.1186/s12888-024-06237-6

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Abstract Background The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in distinguishing patients with affective and anxiety disorders from healthy controls (HCs). Methods We recruited a total of 122 subjects, comprising 24 patients with bipolar disorder (BD), 34 patients with major depressive disorder (MDD), 29 patients with anxiety disorder (AD), and 35 matched HCs. Three clinician-rated scales and five patient-rated scales were used to quantify clinical symptoms, while four cognitive tests were employed to measure cognitive functions in all subjects. Fisher’s discriminant analysis (FDA) was employed to distinguish patients from HCs, as well as to discriminate patient sub-groups from each other. In the FDA model, the prior probability of each group was set as 0.5 in the two-group classification and 0.25 in the four-group classification. Results The results showed that patient-rated scales achieved higher classification accuracies than clinician-rated scales in identifying MDD and AD from HCs. In contrast, cognitive tests exhibited the lowest accuracy. Conclusions These findings suggest that patient-rated scales might improve the classification accuracy for patients with MDD and AD.
AbstractList Background The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in distinguishing patients with affective and anxiety disorders from healthy controls (HCs). Methods We recruited a total of 122 subjects, comprising 24 patients with bipolar disorder (BD), 34 patients with major depressive disorder (MDD), 29 patients with anxiety disorder (AD), and 35 matched HCs. Three clinician-rated scales and five patient-rated scales were used to quantify clinical symptoms, while four cognitive tests were employed to measure cognitive functions in all subjects. Fisher's discriminant analysis (FDA) was employed to distinguish patients from HCs, as well as to discriminate patient sub-groups from each other. In the FDA model, the prior probability of each group was set as 0.5 in the two-group classification and 0.25 in the four-group classification. Results The results showed that patient-rated scales achieved higher classification accuracies than clinician-rated scales in identifying MDD and AD from HCs. In contrast, cognitive tests exhibited the lowest accuracy. Conclusions These findings suggest that patient-rated scales might improve the classification accuracy for patients with MDD and AD. Keywords: Clinician-rated scales, Patient-rated scales, Cognition, Cross-validation, Classification, Discrimination
The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in distinguishing patients with affective and anxiety disorders from healthy controls (HCs).BACKGROUNDThe current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in distinguishing patients with affective and anxiety disorders from healthy controls (HCs).We recruited a total of 122 subjects, comprising 24 patients with bipolar disorder (BD), 34 patients with major depressive disorder (MDD), 29 patients with anxiety disorder (AD), and 35 matched HCs. Three clinician-rated scales and five patient-rated scales were used to quantify clinical symptoms, while four cognitive tests were employed to measure cognitive functions in all subjects. Fisher's discriminant analysis (FDA) was employed to distinguish patients from HCs, as well as to discriminate patient sub-groups from each other. In the FDA model, the prior probability of each group was set as 0.5 in the two-group classification and 0.25 in the four-group classification.METHODSWe recruited a total of 122 subjects, comprising 24 patients with bipolar disorder (BD), 34 patients with major depressive disorder (MDD), 29 patients with anxiety disorder (AD), and 35 matched HCs. Three clinician-rated scales and five patient-rated scales were used to quantify clinical symptoms, while four cognitive tests were employed to measure cognitive functions in all subjects. Fisher's discriminant analysis (FDA) was employed to distinguish patients from HCs, as well as to discriminate patient sub-groups from each other. In the FDA model, the prior probability of each group was set as 0.5 in the two-group classification and 0.25 in the four-group classification.The results showed that patient-rated scales achieved higher classification accuracies than clinician-rated scales in identifying MDD and AD from HCs. In contrast, cognitive tests exhibited the lowest accuracy.RESULTSThe results showed that patient-rated scales achieved higher classification accuracies than clinician-rated scales in identifying MDD and AD from HCs. In contrast, cognitive tests exhibited the lowest accuracy.These findings suggest that patient-rated scales might improve the classification accuracy for patients with MDD and AD.CONCLUSIONSThese findings suggest that patient-rated scales might improve the classification accuracy for patients with MDD and AD.
The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in distinguishing patients with affective and anxiety disorders from healthy controls (HCs). We recruited a total of 122 subjects, comprising 24 patients with bipolar disorder (BD), 34 patients with major depressive disorder (MDD), 29 patients with anxiety disorder (AD), and 35 matched HCs. Three clinician-rated scales and five patient-rated scales were used to quantify clinical symptoms, while four cognitive tests were employed to measure cognitive functions in all subjects. Fisher's discriminant analysis (FDA) was employed to distinguish patients from HCs, as well as to discriminate patient sub-groups from each other. In the FDA model, the prior probability of each group was set as 0.5 in the two-group classification and 0.25 in the four-group classification. The results showed that patient-rated scales achieved higher classification accuracies than clinician-rated scales in identifying MDD and AD from HCs. In contrast, cognitive tests exhibited the lowest accuracy. These findings suggest that patient-rated scales might improve the classification accuracy for patients with MDD and AD.
Background The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in distinguishing patients with affective and anxiety disorders from healthy controls (HCs). Methods We recruited a total of 122 subjects, comprising 24 patients with bipolar disorder (BD), 34 patients with major depressive disorder (MDD), 29 patients with anxiety disorder (AD), and 35 matched HCs. Three clinician-rated scales and five patient-rated scales were used to quantify clinical symptoms, while four cognitive tests were employed to measure cognitive functions in all subjects. Fisher’s discriminant analysis (FDA) was employed to distinguish patients from HCs, as well as to discriminate patient sub-groups from each other. In the FDA model, the prior probability of each group was set as 0.5 in the two-group classification and 0.25 in the four-group classification. Results The results showed that patient-rated scales achieved higher classification accuracies than clinician-rated scales in identifying MDD and AD from HCs. In contrast, cognitive tests exhibited the lowest accuracy. Conclusions These findings suggest that patient-rated scales might improve the classification accuracy for patients with MDD and AD.
BackgroundThe current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in distinguishing patients with affective and anxiety disorders from healthy controls (HCs).MethodsWe recruited a total of 122 subjects, comprising 24 patients with bipolar disorder (BD), 34 patients with major depressive disorder (MDD), 29 patients with anxiety disorder (AD), and 35 matched HCs. Three clinician-rated scales and five patient-rated scales were used to quantify clinical symptoms, while four cognitive tests were employed to measure cognitive functions in all subjects. Fisher’s discriminant analysis (FDA) was employed to distinguish patients from HCs, as well as to discriminate patient sub-groups from each other. In the FDA model, the prior probability of each group was set as 0.5 in the two-group classification and 0.25 in the four-group classification.ResultsThe results showed that patient-rated scales achieved higher classification accuracies than clinician-rated scales in identifying MDD and AD from HCs. In contrast, cognitive tests exhibited the lowest accuracy.ConclusionsThese findings suggest that patient-rated scales might improve the classification accuracy for patients with MDD and AD.
Abstract Background The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in distinguishing patients with affective and anxiety disorders from healthy controls (HCs). Methods We recruited a total of 122 subjects, comprising 24 patients with bipolar disorder (BD), 34 patients with major depressive disorder (MDD), 29 patients with anxiety disorder (AD), and 35 matched HCs. Three clinician-rated scales and five patient-rated scales were used to quantify clinical symptoms, while four cognitive tests were employed to measure cognitive functions in all subjects. Fisher’s discriminant analysis (FDA) was employed to distinguish patients from HCs, as well as to discriminate patient sub-groups from each other. In the FDA model, the prior probability of each group was set as 0.5 in the two-group classification and 0.25 in the four-group classification. Results The results showed that patient-rated scales achieved higher classification accuracies than clinician-rated scales in identifying MDD and AD from HCs. In contrast, cognitive tests exhibited the lowest accuracy. Conclusions These findings suggest that patient-rated scales might improve the classification accuracy for patients with MDD and AD.
The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in distinguishing patients with affective and anxiety disorders from healthy controls (HCs). We recruited a total of 122 subjects, comprising 24 patients with bipolar disorder (BD), 34 patients with major depressive disorder (MDD), 29 patients with anxiety disorder (AD), and 35 matched HCs. Three clinician-rated scales and five patient-rated scales were used to quantify clinical symptoms, while four cognitive tests were employed to measure cognitive functions in all subjects. Fisher's discriminant analysis (FDA) was employed to distinguish patients from HCs, as well as to discriminate patient sub-groups from each other. In the FDA model, the prior probability of each group was set as 0.5 in the two-group classification and 0.25 in the four-group classification. The results showed that patient-rated scales achieved higher classification accuracies than clinician-rated scales in identifying MDD and AD from HCs. In contrast, cognitive tests exhibited the lowest accuracy. These findings suggest that patient-rated scales might improve the classification accuracy for patients with MDD and AD.
ArticleNumber 785
Audience Academic
Author Zhang, Jing
Chen, Min
Yu, Hao
Ji, Shanling
Zhou, Cong
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Issue 1
Keywords Clinician-rated scales
Cognition
Discrimination
Patient-rated scales
Cross-validation
Classification
Language English
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Snippet Background The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in...
The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in...
Background The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in...
BackgroundThe current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in...
Abstract Background The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function...
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pubmed
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Open Access Repository
Aggregation Database
Index Database
Publisher
StartPage 785
SubjectTerms Accuracy
Adult
Analysis
Anxiety
Anxiety disorders
Anxiety Disorders - classification
Anxiety Disorders - diagnosis
Bipolar disorder
Bipolar Disorder - classification
Bipolar Disorder - diagnosis
Bipolar Disorder - psychology
Care and treatment
Case-Control Studies
Classification
Clinician-rated scales
Cognition
Cognitive ability
Cognitive appraisal
Complications and side effects
Cross-validation
Demographic aspects
Depressive Disorder, Major - classification
Depressive Disorder, Major - diagnosis
Depressive Disorder, Major - psychology
Diagnosis
Discriminant Analysis
Discrimination
Epilepsy
Female
Generalized anxiety disorder
Humans
Insomnia
Major depressive disorder
Male
Medicine
Medicine & Public Health
Mental depression
Mental disorders
Middle Aged
Neuropsychological Tests - standards
Neuropsychological Tests - statistics & numerical data
Patient-rated scales
Patients
Prevalence studies (Epidemiology)
Psychiatric Status Rating Scales - standards
Psychiatrists
Psychiatry
Psychotherapy
Questionnaires
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Title Patient-rated scales improve the classification accuracy for patients with depression and anxiety disorder: a linear discriminant analysis
URI https://link.springer.com/article/10.1186/s12888-024-06237-6
https://www.ncbi.nlm.nih.gov/pubmed/39529055
https://www.proquest.com/docview/3142298281
https://www.proquest.com/docview/3128757977
https://pubmed.ncbi.nlm.nih.gov/PMC11555859
https://doaj.org/article/086b6ba5b3e941028aabd1f57ddbddfc
Volume 24
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