Patient-rated scales improve the classification accuracy for patients with depression and anxiety disorder: a linear discriminant analysis
Background The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in distinguishing patients with affective and anxiety disorders from healthy controls (HCs). Methods We recruited a total of 122 subjects, compri...
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Published in | BMC psychiatry Vol. 24; no. 1; pp. 785 - 10 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
London
BioMed Central
11.11.2024
BioMed Central Ltd BMC |
Subjects | |
Online Access | Get full text |
ISSN | 1471-244X 1471-244X |
DOI | 10.1186/s12888-024-06237-6 |
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Abstract | Background
The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in distinguishing patients with affective and anxiety disorders from healthy controls (HCs).
Methods
We recruited a total of 122 subjects, comprising 24 patients with bipolar disorder (BD), 34 patients with major depressive disorder (MDD), 29 patients with anxiety disorder (AD), and 35 matched HCs. Three clinician-rated scales and five patient-rated scales were used to quantify clinical symptoms, while four cognitive tests were employed to measure cognitive functions in all subjects. Fisher’s discriminant analysis (FDA) was employed to distinguish patients from HCs, as well as to discriminate patient sub-groups from each other. In the FDA model, the prior probability of each group was set as 0.5 in the two-group classification and 0.25 in the four-group classification.
Results
The results showed that patient-rated scales achieved higher classification accuracies than clinician-rated scales in identifying MDD and AD from HCs. In contrast, cognitive tests exhibited the lowest accuracy.
Conclusions
These findings suggest that patient-rated scales might improve the classification accuracy for patients with MDD and AD. |
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AbstractList | Background The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in distinguishing patients with affective and anxiety disorders from healthy controls (HCs). Methods We recruited a total of 122 subjects, comprising 24 patients with bipolar disorder (BD), 34 patients with major depressive disorder (MDD), 29 patients with anxiety disorder (AD), and 35 matched HCs. Three clinician-rated scales and five patient-rated scales were used to quantify clinical symptoms, while four cognitive tests were employed to measure cognitive functions in all subjects. Fisher's discriminant analysis (FDA) was employed to distinguish patients from HCs, as well as to discriminate patient sub-groups from each other. In the FDA model, the prior probability of each group was set as 0.5 in the two-group classification and 0.25 in the four-group classification. Results The results showed that patient-rated scales achieved higher classification accuracies than clinician-rated scales in identifying MDD and AD from HCs. In contrast, cognitive tests exhibited the lowest accuracy. Conclusions These findings suggest that patient-rated scales might improve the classification accuracy for patients with MDD and AD. Keywords: Clinician-rated scales, Patient-rated scales, Cognition, Cross-validation, Classification, Discrimination The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in distinguishing patients with affective and anxiety disorders from healthy controls (HCs).BACKGROUNDThe current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in distinguishing patients with affective and anxiety disorders from healthy controls (HCs).We recruited a total of 122 subjects, comprising 24 patients with bipolar disorder (BD), 34 patients with major depressive disorder (MDD), 29 patients with anxiety disorder (AD), and 35 matched HCs. Three clinician-rated scales and five patient-rated scales were used to quantify clinical symptoms, while four cognitive tests were employed to measure cognitive functions in all subjects. Fisher's discriminant analysis (FDA) was employed to distinguish patients from HCs, as well as to discriminate patient sub-groups from each other. In the FDA model, the prior probability of each group was set as 0.5 in the two-group classification and 0.25 in the four-group classification.METHODSWe recruited a total of 122 subjects, comprising 24 patients with bipolar disorder (BD), 34 patients with major depressive disorder (MDD), 29 patients with anxiety disorder (AD), and 35 matched HCs. Three clinician-rated scales and five patient-rated scales were used to quantify clinical symptoms, while four cognitive tests were employed to measure cognitive functions in all subjects. Fisher's discriminant analysis (FDA) was employed to distinguish patients from HCs, as well as to discriminate patient sub-groups from each other. In the FDA model, the prior probability of each group was set as 0.5 in the two-group classification and 0.25 in the four-group classification.The results showed that patient-rated scales achieved higher classification accuracies than clinician-rated scales in identifying MDD and AD from HCs. In contrast, cognitive tests exhibited the lowest accuracy.RESULTSThe results showed that patient-rated scales achieved higher classification accuracies than clinician-rated scales in identifying MDD and AD from HCs. In contrast, cognitive tests exhibited the lowest accuracy.These findings suggest that patient-rated scales might improve the classification accuracy for patients with MDD and AD.CONCLUSIONSThese findings suggest that patient-rated scales might improve the classification accuracy for patients with MDD and AD. The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in distinguishing patients with affective and anxiety disorders from healthy controls (HCs). We recruited a total of 122 subjects, comprising 24 patients with bipolar disorder (BD), 34 patients with major depressive disorder (MDD), 29 patients with anxiety disorder (AD), and 35 matched HCs. Three clinician-rated scales and five patient-rated scales were used to quantify clinical symptoms, while four cognitive tests were employed to measure cognitive functions in all subjects. Fisher's discriminant analysis (FDA) was employed to distinguish patients from HCs, as well as to discriminate patient sub-groups from each other. In the FDA model, the prior probability of each group was set as 0.5 in the two-group classification and 0.25 in the four-group classification. The results showed that patient-rated scales achieved higher classification accuracies than clinician-rated scales in identifying MDD and AD from HCs. In contrast, cognitive tests exhibited the lowest accuracy. These findings suggest that patient-rated scales might improve the classification accuracy for patients with MDD and AD. Background The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in distinguishing patients with affective and anxiety disorders from healthy controls (HCs). Methods We recruited a total of 122 subjects, comprising 24 patients with bipolar disorder (BD), 34 patients with major depressive disorder (MDD), 29 patients with anxiety disorder (AD), and 35 matched HCs. Three clinician-rated scales and five patient-rated scales were used to quantify clinical symptoms, while four cognitive tests were employed to measure cognitive functions in all subjects. Fisher’s discriminant analysis (FDA) was employed to distinguish patients from HCs, as well as to discriminate patient sub-groups from each other. In the FDA model, the prior probability of each group was set as 0.5 in the two-group classification and 0.25 in the four-group classification. Results The results showed that patient-rated scales achieved higher classification accuracies than clinician-rated scales in identifying MDD and AD from HCs. In contrast, cognitive tests exhibited the lowest accuracy. Conclusions These findings suggest that patient-rated scales might improve the classification accuracy for patients with MDD and AD. BackgroundThe current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in distinguishing patients with affective and anxiety disorders from healthy controls (HCs).MethodsWe recruited a total of 122 subjects, comprising 24 patients with bipolar disorder (BD), 34 patients with major depressive disorder (MDD), 29 patients with anxiety disorder (AD), and 35 matched HCs. Three clinician-rated scales and five patient-rated scales were used to quantify clinical symptoms, while four cognitive tests were employed to measure cognitive functions in all subjects. Fisher’s discriminant analysis (FDA) was employed to distinguish patients from HCs, as well as to discriminate patient sub-groups from each other. In the FDA model, the prior probability of each group was set as 0.5 in the two-group classification and 0.25 in the four-group classification.ResultsThe results showed that patient-rated scales achieved higher classification accuracies than clinician-rated scales in identifying MDD and AD from HCs. In contrast, cognitive tests exhibited the lowest accuracy.ConclusionsThese findings suggest that patient-rated scales might improve the classification accuracy for patients with MDD and AD. Abstract Background The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in distinguishing patients with affective and anxiety disorders from healthy controls (HCs). Methods We recruited a total of 122 subjects, comprising 24 patients with bipolar disorder (BD), 34 patients with major depressive disorder (MDD), 29 patients with anxiety disorder (AD), and 35 matched HCs. Three clinician-rated scales and five patient-rated scales were used to quantify clinical symptoms, while four cognitive tests were employed to measure cognitive functions in all subjects. Fisher’s discriminant analysis (FDA) was employed to distinguish patients from HCs, as well as to discriminate patient sub-groups from each other. In the FDA model, the prior probability of each group was set as 0.5 in the two-group classification and 0.25 in the four-group classification. Results The results showed that patient-rated scales achieved higher classification accuracies than clinician-rated scales in identifying MDD and AD from HCs. In contrast, cognitive tests exhibited the lowest accuracy. Conclusions These findings suggest that patient-rated scales might improve the classification accuracy for patients with MDD and AD. The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in distinguishing patients with affective and anxiety disorders from healthy controls (HCs). We recruited a total of 122 subjects, comprising 24 patients with bipolar disorder (BD), 34 patients with major depressive disorder (MDD), 29 patients with anxiety disorder (AD), and 35 matched HCs. Three clinician-rated scales and five patient-rated scales were used to quantify clinical symptoms, while four cognitive tests were employed to measure cognitive functions in all subjects. Fisher's discriminant analysis (FDA) was employed to distinguish patients from HCs, as well as to discriminate patient sub-groups from each other. In the FDA model, the prior probability of each group was set as 0.5 in the two-group classification and 0.25 in the four-group classification. The results showed that patient-rated scales achieved higher classification accuracies than clinician-rated scales in identifying MDD and AD from HCs. In contrast, cognitive tests exhibited the lowest accuracy. These findings suggest that patient-rated scales might improve the classification accuracy for patients with MDD and AD. |
ArticleNumber | 785 |
Audience | Academic |
Author | Zhang, Jing Chen, Min Yu, Hao Ji, Shanling Zhou, Cong |
Author_xml | – sequence: 1 givenname: Shanling surname: Ji fullname: Ji, Shanling organization: Institute of Mental Health, Jining Medical University – sequence: 2 givenname: Jing surname: Zhang fullname: Zhang, Jing organization: Department of Psychiatry, Shandong Daizhuang Hospital – sequence: 3 givenname: Cong surname: Zhou fullname: Zhou, Cong organization: Institute of Mental Health, Jining Medical University – sequence: 4 givenname: Min surname: Chen fullname: Chen, Min email: cm7697@163.com organization: Institute of Mental Health, Jining Medical University, Department of Psychiatry, Shandong Daizhuang Hospital – sequence: 5 givenname: Hao surname: Yu fullname: Yu, Hao email: yuhao@mail.jnmc.edu.cn organization: Institute of Mental Health, Jining Medical University |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/39529055$$D View this record in MEDLINE/PubMed |
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Keywords | Clinician-rated scales Cognition Discrimination Patient-rated scales Cross-validation Classification |
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The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in... The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in... Background The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in... BackgroundThe current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function tests in... Abstract Background The current study aimed to investigate the performances of clinical scales rated by clinicians and patients as well as cognitive function... |
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SubjectTerms | Accuracy Adult Analysis Anxiety Anxiety disorders Anxiety Disorders - classification Anxiety Disorders - diagnosis Bipolar disorder Bipolar Disorder - classification Bipolar Disorder - diagnosis Bipolar Disorder - psychology Care and treatment Case-Control Studies Classification Clinician-rated scales Cognition Cognitive ability Cognitive appraisal Complications and side effects Cross-validation Demographic aspects Depressive Disorder, Major - classification Depressive Disorder, Major - diagnosis Depressive Disorder, Major - psychology Diagnosis Discriminant Analysis Discrimination Epilepsy Female Generalized anxiety disorder Humans Insomnia Major depressive disorder Male Medicine Medicine & Public Health Mental depression Mental disorders Middle Aged Neuropsychological Tests - standards Neuropsychological Tests - statistics & numerical data Patient-rated scales Patients Prevalence studies (Epidemiology) Psychiatric Status Rating Scales - standards Psychiatrists Psychiatry Psychotherapy Questionnaires |
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Title | Patient-rated scales improve the classification accuracy for patients with depression and anxiety disorder: a linear discriminant analysis |
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