功能磁共振成像在神经外科应用的初步经验

R445.2; 背景与目的:位于脑中央沟附近的肿瘤在外科手术中易造成运动功能损伤.本研究拟运用功能磁共振成像(functional magnetic resonance imaging,fMRI)的方法术前确定手运动功能皮层的位置及其与肿瘤的关系,探索fMRI在神经外科的应用价值.方法:31例位于中央沟附近的脑肿瘤患者接受常规和功能磁共振检查,其中转移瘤10例,胶质瘤11例,脑膜瘤6例,动静脉畸形2例,蛛网膜囊肿2例.功能成像方法采用在手静止和开合运动中,行快速梯度平面回波连续成像,以平行胼胝体前后联合的连线为基线,连续16层,层厚为4 mm,层距为零,共获得1280幅功能原始图像,并经处理获...

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Published in癌症 Vol. 25; no. 3; pp. 343 - 347
Main Authors 黄穗乔, 梁碧玲, 谢榜昆, 钟镜联, 张湛, 张嵘
Format Journal Article
LanguageChinese
Published 中山大学第二附属医院放射科,广东,广州,510120 2006
Subjects
脑肿瘤
功能磁共振成像
神经外科
应用
Online AccessGet full text
ISSN1000-467X
DOI10.3321/j.issn:1000-467X.2006.03.017

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Abstract R445.2; 背景与目的:位于脑中央沟附近的肿瘤在外科手术中易造成运动功能损伤.本研究拟运用功能磁共振成像(functional magnetic resonance imaging,fMRI)的方法术前确定手运动功能皮层的位置及其与肿瘤的关系,探索fMRI在神经外科的应用价值.方法:31例位于中央沟附近的脑肿瘤患者接受常规和功能磁共振检查,其中转移瘤10例,胶质瘤11例,脑膜瘤6例,动静脉畸形2例,蛛网膜囊肿2例.功能成像方法采用在手静止和开合运动中,行快速梯度平面回波连续成像,以平行胼胝体前后联合的连线为基线,连续16层,层厚为4 mm,层距为零,共获得1280幅功能原始图像,并经处理获得统计学Z-score图.结果:除2例患者头运动较明显外,其余患者都显示了手运动功能皮层活化兴奋区,并测得了功能皮层区与肿瘤的最短距离.功能皮层活化区表现出3种不同类型,包括:病灶内或边缘散在的活化小斑点;功能皮层活化区受挤压、移位;功能皮层活化区形态,位置正常.此外,在其他区域亦出现了不同例数的活化现象.结论:fMRI能帮助确定中央沟附近的脑肿瘤与手运动功能区位置的关系,从而为外科手术提供参考.
AbstractList R445.2; 背景与目的:位于脑中央沟附近的肿瘤在外科手术中易造成运动功能损伤.本研究拟运用功能磁共振成像(functional magnetic resonance imaging,fMRI)的方法术前确定手运动功能皮层的位置及其与肿瘤的关系,探索fMRI在神经外科的应用价值.方法:31例位于中央沟附近的脑肿瘤患者接受常规和功能磁共振检查,其中转移瘤10例,胶质瘤11例,脑膜瘤6例,动静脉畸形2例,蛛网膜囊肿2例.功能成像方法采用在手静止和开合运动中,行快速梯度平面回波连续成像,以平行胼胝体前后联合的连线为基线,连续16层,层厚为4 mm,层距为零,共获得1280幅功能原始图像,并经处理获得统计学Z-score图.结果:除2例患者头运动较明显外,其余患者都显示了手运动功能皮层活化兴奋区,并测得了功能皮层区与肿瘤的最短距离.功能皮层活化区表现出3种不同类型,包括:病灶内或边缘散在的活化小斑点;功能皮层活化区受挤压、移位;功能皮层活化区形态,位置正常.此外,在其他区域亦出现了不同例数的活化现象.结论:fMRI能帮助确定中央沟附近的脑肿瘤与手运动功能区位置的关系,从而为外科手术提供参考.
Author 张湛
黄穗乔
张嵘
梁碧玲
谢榜昆
钟镜联
AuthorAffiliation 中山大学第二附属医院放射科,广东,广州,510120
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ZHONG Jing-Lian
XIE Bang-Kun
ZHANG Zhan
LIANG Bi-Ling
ZHANG Rong
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功能磁共振成像
神经外科
应用
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Snippet R445.2; 背景与目的:位于脑中央沟附近的肿瘤在外科手术中易造成运动功能损伤.本研究拟运用功能磁共振成像(functional magnetic resonance imaging,fMRI)的方法术前确定手...
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Title 功能磁共振成像在神经外科应用的初步经验
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