Dedicator of cytokinesis 8 regulates signal transducer and activator of transcription 3 activation and promotes TH17 cell differentiation - Keles, Sevgi; Charbonnier, Louis Marie; Kabaleeswaran, Venkataraman; Reisli, Ismail; Genel, Ferah; Gulez, Nesrin; Al-Herz, Waleed; Ramesh, Narayanaswamy; Perez-Atayde, Antonio; Karaca, Neslihan E.; Kutukculer, Necil; Wu, Hao; et al. (Journal of allergy and clinical immunology, 2016)
Keywords: Bacterial infections; Cell division; Cell division cycle 42; Crystal structure; dedicator of cytokinesis 8; guanine nucleotide exchange factor; hyper-IgE syndrome; Infections; Liver; Microscopy; mucocutaneous candidiasis; Mutation; Patients; Phosphorylation; Proteins; signal transducer and activator of transcription 3; suppressor of cytokine signaling 3; TH17; suppressor of cytokine signaling 3; IL-6R; AD; DOCK8; GEF; signal transducer and activator of transcription 3; SOCS; ChIP; hyper-IgE syndrome; dedicator of cytokinesis 8; HIES; AR; Na3VO4; STAT; guanine nucleotide exchange factor; Cell division cycle 42; mucocutaneous candidiasis; pSTAT3; Rac1; TH17; GAPDH; WT; Cdc42; RORγt