Nearly fatal ventricular arrhythmia following pacemaker implantation in a young female with complete heart block

This case concerns a 24‐year‐old female who developed malignant ventricular tachyarrhythmia a few weeks after pacemaker implantation for complete heart block. Apparently, right ventricular pacing caused significant repolarization abnormalities in both native and paced rhythms with marked QT prolonga...

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Published inJournal of arrhythmia Vol. 35; no. 5; pp. 766 - 769
Main Authors Ali, Hussam, Lupo, Pierpaolo, Foresti, Sara, De Ambroggi, Guido, Mantovani, Riccardo, De Lucia, Carmine, Passarelli, Ilaria, De Ambroggi, Luigi, Cappato, Riccardo
Format Journal Article
LanguageEnglish
Published Hoboken John Wiley & Sons, Inc 01.10.2019
John Wiley and Sons Inc
Wiley
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ISSN1880-4276
1883-2148
1883-2148
DOI10.1002/joa3.12220

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Abstract This case concerns a 24‐year‐old female who developed malignant ventricular tachyarrhythmia a few weeks after pacemaker implantation for complete heart block. Apparently, right ventricular pacing caused significant repolarization abnormalities in both native and paced rhythms with marked QT prolongation and substantial electrical instability. This case highlights other intriguing phenomena in the puzzle of cardiac repolarization and how pacing therapy may alter this complex process providing arrhythmic substrate in vulnerable subjects. Though such arrhythmic events are clinically rare, vulnerable patients or with suspected myocardial disease that may cause QT prolongation should be carefully followed in the course of pacing therapy.
AbstractList This case concerns a 24-year-old female who developed malignant ventricular tachyarrhythmia a few weeks after pacemaker implantation for complete heart block. Apparently, right ventricular pacing caused significant repolarization abnormalities in both native and paced rhythms with marked QT prolongation and substantial electrical instability. This case highlights other intriguing phenomena in the puzzle of cardiac repolarization and how pacing therapy may alter this complex process providing arrhythmic substrate in vulnerable subjects. Though such arrhythmic events are clinically rare, vulnerable patients or with suspected myocardial disease that may cause QT prolongation should be carefully followed in the course of pacing therapy.This case concerns a 24-year-old female who developed malignant ventricular tachyarrhythmia a few weeks after pacemaker implantation for complete heart block. Apparently, right ventricular pacing caused significant repolarization abnormalities in both native and paced rhythms with marked QT prolongation and substantial electrical instability. This case highlights other intriguing phenomena in the puzzle of cardiac repolarization and how pacing therapy may alter this complex process providing arrhythmic substrate in vulnerable subjects. Though such arrhythmic events are clinically rare, vulnerable patients or with suspected myocardial disease that may cause QT prolongation should be carefully followed in the course of pacing therapy.
Abstract This case concerns a 24‐year‐old female who developed malignant ventricular tachyarrhythmia a few weeks after pacemaker implantation for complete heart block. Apparently, right ventricular pacing caused significant repolarization abnormalities in both native and paced rhythms with marked QT prolongation and substantial electrical instability. This case highlights other intriguing phenomena in the puzzle of cardiac repolarization and how pacing therapy may alter this complex process providing arrhythmic substrate in vulnerable subjects. Though such arrhythmic events are clinically rare, vulnerable patients or with suspected myocardial disease that may cause QT prolongation should be carefully followed in the course of pacing therapy.
This case concerns a 24-year-old female who developed malignant ventricular tachyarrhythmia a few weeks after pacemaker implantation for complete heart block. Apparently, right ventricular pacing caused significant repolarization abnormalities in both native and paced rhythms with marked QT prolongation and substantial electrical instability. This case highlights other intriguing phenomena in the puzzle of cardiac repolarization and how pacing therapy may alter this complex process providing arrhythmic substrate in vulnerable subjects. Though such arrhythmic events are clinically rare, vulnerable patients or with suspected myocardial disease that may cause QT prolongation should be carefully followed in the course of pacing therapy.
Audience Academic
Author De Lucia, Carmine
Foresti, Sara
De Ambroggi, Guido
Lupo, Pierpaolo
Ali, Hussam
Mantovani, Riccardo
Cappato, Riccardo
Passarelli, Ilaria
De Ambroggi, Luigi
AuthorAffiliation 1 Arrhythmia & EP Research Center IRCCS Humanitas Research & University Hospital Rozzano (Milan) Italy
2 University of Milan Milan Italy
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Cites_doi 10.1016/j.hrthm.2014.08.026
10.1016/0002-9149(82)90169-2
10.1161/01.CIR.100.24.2431
10.1111/jce.13203
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Copyright 2019 The Authors. published by John Wiley & Sons Australia, Ltd on behalf of the Japanese Heart Rhythm Society.
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Snippet This case concerns a 24‐year‐old female who developed malignant ventricular tachyarrhythmia a few weeks after pacemaker implantation for complete heart block....
This case concerns a 24-year-old female who developed malignant ventricular tachyarrhythmia a few weeks after pacemaker implantation for complete heart block....
Abstract This case concerns a 24‐year‐old female who developed malignant ventricular tachyarrhythmia a few weeks after pacemaker implantation for complete...
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SubjectTerms Cardiac patients
Case Report
Case Reports
complete heart block
Disease susceptibility
Heart
Heart block
long QT
pacemaker
Tachycardia
ventricular repolarization
ventricular tachyarrhythmia
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Title Nearly fatal ventricular arrhythmia following pacemaker implantation in a young female with complete heart block
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