Aortic and Mitral Valve Replacement Due to Extensive Inflammatory Immunoglobulin G4–Related Pseudotumor

A 64-year-old woman with extensive tumorous infiltration of the mitral and aortic valves underwent partial resection of a tumor of the left ventricular outflow tract and replacement of both affected valves. Histology revealed an inflammatory pseudotumor with a significant number of immunoglobulin-G4...

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Published inThe Annals of thoracic surgery Vol. 100; no. 4; pp. 1439 - 1441
Main Authors Besik, Josef, Pirk, Jan, Netuka, Ivan, Szarszoi, Ondrej, Marek, Tomas, Urban, Marian, Honsova, Eva, Laco, Jan
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Inc 01.10.2015
Subjects
Aortic Valve - surgery
Cardiothoracic Surgery
Female
Granuloma, Plasma Cell - complications
Granuloma, Plasma Cell - immunology
Heart Valve Diseases - etiology
Heart Valve Diseases - surgery
Heart Valve Prosthesis Implantation
Humans
Immunoglobulin G
Middle Aged
Mitral Valve - surgery
Surgery
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ISSN0003-4975
1552-6259
1552-6259
DOI10.1016/j.athoracsur.2014.12.051

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Summary:A 64-year-old woman with extensive tumorous infiltration of the mitral and aortic valves underwent partial resection of a tumor of the left ventricular outflow tract and replacement of both affected valves. Histology revealed an inflammatory pseudotumor with a significant number of immunoglobulin-G4–positive plasma cells. The histologic and clinical findings suggested immunoglobulin-G4–related disease of the heart.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ISSN:0003-4975
1552-6259
1552-6259
DOI:10.1016/j.athoracsur.2014.12.051