Nomograms for two-dimensional echocardiography derived valvular and arterial dimensions in Caucasian children

Despite recent advances, current pediatric echocardiographic nomograms for valvular and arterial dimensions remain limited. We prospectively studied healthy Caucasian Italian children by two-dimensional (2D) echocardiography. Echocardiographic measurements for 18 valvular and arterial dimensions wer...

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Published inJournal of cardiology Vol. 69; no. 1; pp. 208 - 215
Main Authors Cantinotti, Massimiliano, Giordano, Raffaele, Scalese, Marco, Murzi, Bruno, Assanta, Nadia, Spadoni, Isabella, Maura, Crocetti, Marco, Marotta, Molinaro, Sabrina, Kutty, Shelby, Iervasi, Giorgio
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Ltd 01.01.2017
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Online AccessGet full text
ISSN0914-5087
1876-4738
1876-4738
DOI10.1016/j.jjcc.2016.03.010

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Abstract Despite recent advances, current pediatric echocardiographic nomograms for valvular and arterial dimensions remain limited. We prospectively studied healthy Caucasian Italian children by two-dimensional (2D) echocardiography. Echocardiographic measurements for 18 valvular and arterial dimensions were performed and models were generated testing for linear, logarithmic, exponential, and square root relationships. Heteroscedasticity was accounted for by White or Breusch–Pagan test. Age, weight, height, heart rate, and body surface area (BSA) were used as independent variables in different analyses to predict the mean values of each measurement. Structured Z-scores were then computed. In all, 1151 subjects (age 0 days to 17 years; 45% females; BSA 0.12–2.12m2) were studied. The Haycock formula was used when presenting data as predicted values (mean±2 SDs) for a given BSA and within equations relating echocardiographic measurements to BSA. The predicted values and Z-score boundaries for all measurements are presented. We report echocardiographic nomograms for valvular and arterial dimensions derived from a large population of children. Integration of these data with those of previous reports would allow for a comprehensive coverage of pediatric 2D echocardiographic nomograms for measurement of 2D cardiac structures.
AbstractList Despite recent advances, current pediatric echocardiographic nomograms for valvular and arterial dimensions remain limited. We prospectively studied healthy Caucasian Italian children by two-dimensional (2D) echocardiography. Echocardiographic measurements for 18 valvular and arterial dimensions were performed and models were generated testing for linear, logarithmic, exponential, and square root relationships. Heteroscedasticity was accounted for by White or Breusch-Pagan test. Age, weight, height, heart rate, and body surface area (BSA) were used as independent variables in different analyses to predict the mean values of each measurement. Structured Z-scores were then computed. In all, 1151 subjects (age 0 days to 17 years; 45% females; BSA 0.12-2.12m ) were studied. The Haycock formula was used when presenting data as predicted values (mean±2 SDs) for a given BSA and within equations relating echocardiographic measurements to BSA. The predicted values and Z-score boundaries for all measurements are presented. We report echocardiographic nomograms for valvular and arterial dimensions derived from a large population of children. Integration of these data with those of previous reports would allow for a comprehensive coverage of pediatric 2D echocardiographic nomograms for measurement of 2D cardiac structures.
Abstract Background Despite recent advances, current pediatric echocardiographic nomograms for valvular and arterial dimensions remain limited. Methods We prospectively studied healthy Caucasian Italian children by two-dimensional (2D) echocardiography. Echocardiographic measurements for 18 valvular and arterial dimensions were performed and models were generated testing for linear, logarithmic, exponential, and square root relationships. Heteroscedasticity was accounted for by White or Breusch–Pagan test. Age, weight, height, heart rate, and body surface area (BSA) were used as independent variables in different analyses to predict the mean values of each measurement. Structured Z -scores were then computed. Results In all, 1151 subjects (age 0 days to 17 years; 45% females; BSA 0.12–2.12 m2 ) were studied. The Haycock formula was used when presenting data as predicted values (mean ± 2 SDs) for a given BSA and within equations relating echocardiographic measurements to BSA. The predicted values and Z -score boundaries for all measurements are presented. Conclusions We report echocardiographic nomograms for valvular and arterial dimensions derived from a large population of children. Integration of these data with those of previous reports would allow for a comprehensive coverage of pediatric 2D echocardiographic nomograms for measurement of 2D cardiac structures.
Despite recent advances, current pediatric echocardiographic nomograms for valvular and arterial dimensions remain limited. We prospectively studied healthy Caucasian Italian children by two-dimensional (2D) echocardiography. Echocardiographic measurements for 18 valvular and arterial dimensions were performed and models were generated testing for linear, logarithmic, exponential, and square root relationships. Heteroscedasticity was accounted for by White or Breusch–Pagan test. Age, weight, height, heart rate, and body surface area (BSA) were used as independent variables in different analyses to predict the mean values of each measurement. Structured Z-scores were then computed. In all, 1151 subjects (age 0 days to 17 years; 45% females; BSA 0.12–2.12m2) were studied. The Haycock formula was used when presenting data as predicted values (mean±2 SDs) for a given BSA and within equations relating echocardiographic measurements to BSA. The predicted values and Z-score boundaries for all measurements are presented. We report echocardiographic nomograms for valvular and arterial dimensions derived from a large population of children. Integration of these data with those of previous reports would allow for a comprehensive coverage of pediatric 2D echocardiographic nomograms for measurement of 2D cardiac structures.
Despite recent advances, current pediatric echocardiographic nomograms for valvular and arterial dimensions remain limited.BACKGROUNDDespite recent advances, current pediatric echocardiographic nomograms for valvular and arterial dimensions remain limited.We prospectively studied healthy Caucasian Italian children by two-dimensional (2D) echocardiography. Echocardiographic measurements for 18 valvular and arterial dimensions were performed and models were generated testing for linear, logarithmic, exponential, and square root relationships. Heteroscedasticity was accounted for by White or Breusch-Pagan test. Age, weight, height, heart rate, and body surface area (BSA) were used as independent variables in different analyses to predict the mean values of each measurement. Structured Z-scores were then computed.METHODSWe prospectively studied healthy Caucasian Italian children by two-dimensional (2D) echocardiography. Echocardiographic measurements for 18 valvular and arterial dimensions were performed and models were generated testing for linear, logarithmic, exponential, and square root relationships. Heteroscedasticity was accounted for by White or Breusch-Pagan test. Age, weight, height, heart rate, and body surface area (BSA) were used as independent variables in different analyses to predict the mean values of each measurement. Structured Z-scores were then computed.In all, 1151 subjects (age 0 days to 17 years; 45% females; BSA 0.12-2.12m2) were studied. The Haycock formula was used when presenting data as predicted values (mean±2 SDs) for a given BSA and within equations relating echocardiographic measurements to BSA. The predicted values and Z-score boundaries for all measurements are presented.RESULTSIn all, 1151 subjects (age 0 days to 17 years; 45% females; BSA 0.12-2.12m2) were studied. The Haycock formula was used when presenting data as predicted values (mean±2 SDs) for a given BSA and within equations relating echocardiographic measurements to BSA. The predicted values and Z-score boundaries for all measurements are presented.We report echocardiographic nomograms for valvular and arterial dimensions derived from a large population of children. Integration of these data with those of previous reports would allow for a comprehensive coverage of pediatric 2D echocardiographic nomograms for measurement of 2D cardiac structures.CONCLUSIONSWe report echocardiographic nomograms for valvular and arterial dimensions derived from a large population of children. Integration of these data with those of previous reports would allow for a comprehensive coverage of pediatric 2D echocardiographic nomograms for measurement of 2D cardiac structures.
Author Assanta, Nadia
Molinaro, Sabrina
Giordano, Raffaele
Spadoni, Isabella
Iervasi, Giorgio
Maura, Crocetti
Marco, Marotta
Kutty, Shelby
Cantinotti, Massimiliano
Scalese, Marco
Murzi, Bruno
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Keywords Echocardiography
Nomograms
Children
Language English
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Snippet Despite recent advances, current pediatric echocardiographic nomograms for valvular and arterial dimensions remain limited. We prospectively studied healthy...
Abstract Background Despite recent advances, current pediatric echocardiographic nomograms for valvular and arterial dimensions remain limited. Methods We...
Despite recent advances, current pediatric echocardiographic nomograms for valvular and arterial dimensions remain limited.BACKGROUNDDespite recent advances,...
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StartPage 208
SubjectTerms Adolescent
Arteries - diagnostic imaging
Body Surface Area
Body Weight
Cardiovascular
Child
Child, Preschool
Children
Echocardiography
Echocardiography - methods
Echocardiography - statistics & numerical data
European Continental Ancestry Group
Female
Healthy Volunteers
Heart Valves - diagnostic imaging
Humans
Infant
Infant, Newborn
Italy
Male
Nomograms
Prospective Studies
Reference Values
Title Nomograms for two-dimensional echocardiography derived valvular and arterial dimensions in Caucasian children
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https://dx.doi.org/10.1016/j.jjcc.2016.03.010
https://www.ncbi.nlm.nih.gov/pubmed/27118699
https://www.proquest.com/docview/1826668763
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