Genome-wide mapping of long-range contacts unveils clustering of DNA double-strand breaks at damaged active genes - Aymard, François; Aguirrebengoa, Marion; Guillou, Emmanuelle; Javierre, Biola M; Bugler, Beatrix; Arnould, Coline; Rocher, Vincent; Iacovoni, Jason S; Biernacka, Anna; Skrzypczak, Magdalena; Ginalski, Krzysztof; Rowicka, Maga; et al. (Nature structural & molecular biology, 2017)
Keywords: 38/22; 45/23; 45/77; 631/337/1427/2122; 631/337/386; Active sites (Biochemistry); Biochemistry; Biological Microscopy; Cell Line; Chromosome Mapping; Chromosomes; Cluster Analysis; Deoxyribonucleic acid; DNA; DNA Breaks, Double-Stranded - drug effects; DNA repair; DNA Repair - drug effects; DNA Repair - genetics; DNA Replication - drug effects; DNA Replication - genetics; DNA, Intergenic - genetics; G1 Phase - drug effects; G1 Phase - genetics; Genes; Genome, Human; Genomes; Histones - metabolism; Humans; Life Sciences; Membrane Biology; Methods; Models, Biological; Nuclear Proteins - metabolism; Observations; Properties; Protein Domains; Protein Structure; Recombination, Genetic - drug effects; RNA, Small Interfering - metabolism; Tamoxifen - analogs & derivatives; Tamoxifen - pharmacology; Transcription, Genetic - drug effects; Translocation; Yeasts