The Effects of Ivacaftor on Bone Density and Microarchitecture in Children and Adults with Cystic Fibrosis - Putman, Melissa S; Greenblatt, Logan B; Bruce, Michael; Joseph, Taisha; Lee, Hang; Sawicki, Gregory; Uluer, Ahmet; Sicilian, Leonard; Neuringer, Isabel; Gordon, Catherine M; Bouxsein, Mary L; Finkelstein, Joel S (The journal of clinical endocrinology and metabolism, 2021)
Keywords: Adolescent; Adult; Aged; Amino Acid Substitution; Aminophenols - pharmacology; Aminophenols - therapeutic use; Analysis; Bone and Bones - drug effects; Bone and Bones - pathology; Bone and Bones - ultrastructure; Bone density; Bone Density - drug effects; Bone diseases; Bone mineral density; Bone strength; Bone turnover; Bones; Cancellous bone; Case-Control Studies; Child; Children; Clinical s; Cohort Studies; Computed tomography; Cystic fibrosis; Cystic Fibrosis - drug therapy; Cystic Fibrosis - genetics; Cystic Fibrosis - metabolism; Cystic Fibrosis - pathology; Cystic Fibrosis Transmembrane Conductance Regulator - genetics; Density; Dual energy X-ray absorptiometry; Female; Humans; Ivacaftor; Male; Medical colleges; Medical research; Medicine, Experimental; Middle Aged; Mutation; Mutation, Missense; Patients; Porosity; Quinolones - pharmacology; Quinolones - therapeutic use; Radius; Tibia; United States; Young Adult; United States; Massachusetts; bone mineral density; dual energy X-ray absorptiometry; Ivacaftor; cystic fibrosis; high-resolution peripheral quantitative computed tomography; bone microarchitecture