Application of a validated ultra performance liquid chromatography–tandem mass spectrometry method for the quantification of darunavir in human plasma for a bioequivalence study in Indian subjects - Gupta, Ajay; Singhal, Puran; Shrivastav, Pranav S.; Sanyal, Mallika (Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011)
Keywords: Analysis; Analytical, structural and metabolic biochemistry; Bioequivalence study; Biological and medical sciences; Chromatography; Chromatography, High Pressure Liquid - methods; Darunavir; Fundamental and applied biological sciences. Psychology; General pharmacology; Human; Human plasma; Humans; Incurred sample reanalysis; India; Indian; Linearity; liquid chromatography; liquid-liquid extraction; Liquids; Mass spectrometry; Medical sciences; monitoring; particle size; pharmacokinetics; Pharmacology. Drug treatments; proteinase inhibitors; Recovery; Reproducibility; spectrometers; Sulfonamides - blood; Sulfonamides - pharmacokinetics; tandem mass spectrometry; Tandem Mass Spectrometry - methods; Therapeutic Equivalency; UPLC–MS/MS; Asia; India; Bioequivalence study; Human plasma; Darunavir; UPLC–MS/MS; Incurred sample reanalysis; Human; Validation; Biological fluid; Antiretroviral agent; Sulfonamide; Bioequivalence; Non peptide compound; Blood plasma; Antiviral; UPLC-MS/MS; Pharmacokinetics; Protease inhibitor; Quantitative analysis