Down-regulation of oxidative stress and COX-2 and iNOS expressions by dimethyl lithospermate in aged rat kidney - Choi, Yeon Ja; Kim, Hyung Suk; Lee, Juyoun; Chung, Jin; Lee, Jun Sik; Choi, Jae Sue; Yoon, Taek Rim; Kim, Hyung Keun; Chung, Hae Young (Archives of pharmacal research, 2014)
Keywords: Aging - metabolism; Animals; Antioxidants - administration & dosage; Antioxidants - isolation & purification; Antioxidants - therapeutic use; Benzofurans - administration & dosage; Benzofurans - isolation & purification; Benzofurans - therapeutic use; Cyclooxygenase 2 - biosynthesis; cytotoxicity; DNA; dose response; Down-Regulation; inducible nitric oxide synthase; kidneys; lipids; Male; Medicine; metabolites; nitric oxide; Nitric Oxide - metabolism; Nitric Oxide Synthase Type II - biosynthesis; oxidative stress; Oxidative Stress - drug effects; Peroxynitrous Acid - metabolism; Pharmacology/Toxicology; Pharmacy; prostaglandin synthase; proteins; rats; Rats, Sprague-Dawley; Reactive Oxygen Species - metabolism; Research Article; Salvia miltiorrhiza; Salvia miltiorrhiza - chemistry; superoxide anion; Western blotting; 약학; Aging; iNOS; ONOO; COX-2; Reactive species; Dimethyl lithospermate